Clomiphene Citrate (CC or Clomid) – A Testosterone Therapy Alternative for Men with Low Testosterone Levels

Shira Miller, M.D.Men512 Comments

A Testosterone Therapy Alternative for Men with Low Testosterone Levels

Whether you are a 30, 50, 80 or even 110 year old man, having low testosterone levels (hypogonadism) is neither fun nor healthy. The symptoms of low testosterone in men range from lack of energy, depressed mood, loss of vitality, muscle atrophy (sarcopenia), muscles aches, low libido, erectile dysfunction, and weight gain…to bone loss (osteopenia), osteoporosis, mild anemia, increased risk of Alzheimer’s, increased risk of high-grade prostate cancer, and increased risk of death due to all causes.1

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As you may know, low testosterone in men may be caused by problems in the testes (or gonads). This is called primary hypogonadism and can be brought on by the mumps, testicular trauma, or testicular cancer, etc., and can only be treated with testosterone replacement therapy. However, the more common causes of low testosterone/hypogonadism result from problems in the pituitary gland and/or hypothalamus in a man’s brain. Low testosterone levels caused by such “brain problems” are collectively described as secondary hypogonadism or hypogonadotropic hypogonadism and may result from depression/anxiety, head trauma, iron overload, anabolic steroid overdosing, diabetes, sleep deprivation, or some medications.

Traditionally, if low testosterone is diagnosed, testosterone replacement therapy is prescribed, and it most commonly comes in the form of a cream, gel, pellet, patch, and by injection. And although these types of therapy are effective, some methods are better than others, and there are side-effects with all of them. For example, testicular shrinkage, gynecomastia (breast enlargement), low sperm count/sterility, and polycythemia (overproduction of red blood cells) are common side-effects of testosterone replacement therapy (for many sufferers, these side-effects are mostly treatable or considered “worth it” by the patient).

However, specifically due to the sterility side-effect, such testosterone treatments aren’t a good option for men who want to have children. In these (usually young) hypogonadal men, clomiphene citrate (CC or Clomid) and/or human chorionic gonadotropin (HCG) have been used (by specialists) for decades to increase testosterone production, increase sperm production, and increase fertility. Both these therapies effectively help signal the testes to produce testosterone and thereby increase testosterone levels (assuming of course the cause of the initial problem is not in the testes’ ability to make testosterone). See “David” (below) for an oversimplified diagram of how clomiphene, HCG, and testosterone work within the hypothalamic-pituitary-testicular axis.

In a healthy male, the pituitary gland in the brain releases luteinizing hormone (LH) into the blood stream, which signals the testes to “GO” and produce testosterone. After testosterone has been produced it naturally converts to some estrogen (yes, there’s estrogen in men too) and this estrogen acts as a “STOP” signal to the pituitary to stop making LH. It is a delicate system of checks and balances which I have simplified here for our purposes.

Clomid works by blocking estrogen at the pituitary and hypothalamus. Thus, the usual estrogen message to “STOP” production of LH is essentially silenced, and therefore the pituitary makes more LH and there is an increased “GO” signal to produce testosterone in the testes. HCG works by mimicking LH, which also increases the “GO” signal to produce more testosterone in the testes. Prescribing testosterone for a man, however, does the opposite of what clomiphene and HCG do.

With traditional testosterone replacement therapy, the brain (hypothalamus and pituitary) gets the message that there is plenty of testosterone being made in the testes, so much so that it doesn’t need to make anymore. Subsequently, the pituitary stops producing LH, and the natural production of testosterone (and sperm) in the testes ceases, which is why traditional testosterone replacement results in testicular shrinkage and low sperm count…a man’s testosterone and sperm manufacturing plant is essentially shut off.

Clomiphene citrate (CC) and/or HCG do not turn off the testosterone manufacturing plant but rather turn it back on or reboot it. While some hypogonadal men require continuous use of clomiphene, for others it can be used for a 3-6 month time period and then discontinued. And, the checks and balances system is not interrupted, so there aren’t the testosterone replacement side-effects which occur due to intentional or unintentional testosterone overdosing. Most interestingly, although it used to be thought that clomiphene and/or HCG only worked on young men, in the past decade or so it has been used effectively in older men too.

The 5 Main Reasons Clomiphene Citrate (CC or Clomid) May be a Good Alternative to Testosterone Replacement Therapy in Men with Low Testosterone Due to Secondary Hypogonadism:

1. Clomiphene citrate stimulates the body’s own production of testosterone

2. Clomiphene citrate doesn’t interfere with the body’s checks and balances of testosterone

3. Clomiphene citrate comes as a pill easily administered by mouth

4. Clomiphene citrate is generic and very cheap2 

5. Clomiphene citrate has little side-effects and low risk of developing these side-effects3 

The 5 Main Reasons Clomiphene Citrate (CC or Clomid) is Not Usually Prescribed to Men with Low Testosterone Due to Secondary Hypogonadism:

1. Most doctors aren’t aware of the efficacy and safety of clomiphene use in men

2. Most doctors think of Clomid as a “women’s drug” to increase fertility

3. Clomid is FDA approved only for use in women

4. Clomid use in men is considered “off label”

5. Clomiphene citrate is now generic and really inexpensive so it’s not advertised very much

Note: HCG is more commonly known and prescribed for secondary hypogonadism in men but it involves injection and is expensive, so if clomiphene works alone I think that is preferred.

The 4 Main Risks of Using Clomiphene Citrate (CC or Clomid) in Men with Low Testosterone Due to Secondary Hypogonadism:

1. Very rarely, visual changes may occur which are reversible with discontinuation

2. In older men, there is a reported increased risk of pyospermia (a noninfectious increase in white blood cells in semen, with unseen detriment)

3. Clomiphene citrate is a drug which is not bioidentical. This means it’s molecular structure doesn’t mimic a compound naturally found in the human body. And, correspondingly, clomiphene citrate doesn’t have a known natural function in the human body and thus may at some point manifest a currently unknown side-effect in men. This latter, however, is a theoretical risk because for more than 40 years clomiphene use in men has only shown the risks above.

4. Clomiphene may not work…especially in older men who in addition to secondary hypogonadism may also have primary hypogonadism; or in men with an unresolved chronic disease4 

In conclusion, in the appropriate male patient, clomiphene citrate (CC or Clomid) may be a good alternative to both short and long-term testosterone replacement therapy. Regardless, just like testosterone replacement, clomiphene citrate must be administered and monitored by a competent physician.

1. J Clin Endocrinol Metab. 2008 Jan;93(1):68-75.
2. J Sex Med. 2010 Jan;7(1 Pt 1):269-76.
3. BJU Int. 2012 Nov;110(10):1524-8.
4. Int J Impot Res. 2003 Jun;15(3):156-65.

The CC Pill

The Thinking Man's Alternative to Testosterone and Viagra

By Shira Miller, M.D.
The CC Pill will empower you, and teach your doctor how to prescribe the right medication for your Low T.
Sign-up today to the pre-order list!
No payment necessary, and your information will not be shared with third parties.

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  • Matt

    49 year old male with test at 226. Had a prostate infection which caused psa spike. Negative biopsy as well as halo test. Urn wants me to start on axiron. Is clomid an option? My gp had mentioned it before. Dr. Miller: Yes, but depends on if low T is due to primary or secondary hypogonadism.

  • Jerry

    75 year old male been on testosterone injections for over 5 years, 400 mg every 3 weeks, been on clomiphene for 15 days, how long will it take for my testicles to start increasing in size? my energy level is up since I started clomiphene. I take 50mg per day

  • Mike B

    A small dose of clomid 25mg every 2-3 days has proven to be very effective for me (30 male) My question is how long is too long to be on this. Thank you

  • sikoo

    after clomid taken my sperm count and sperm motility normol .that result is forever or some time.pls tell me now i not taken clomid. Dr. Miller: It depends on cause of previously low sperm count and whether that problem was treated.

  • Taylor

    After reading the comments above, it seems your plan doesn’t take the conversion to estradiol. Continued use of HCG or Clomid need an aromotose inhibitor – as doea

  • Anonymous

    Am just so happy tonight because i have been cured from my 9 years weak erection and poor ejaculation by a great doctor Dr Alaska. I do not know how to thank you but hope you will never forget that i will keep on appreciating you untill i die.for any erectile or premature ejaculation problems just reach him he is a are his contacts or call +2348169591194

  • Tom

    Any evidence that clomid for men (25mg every 3 days) can boost estrogen levels and cause excessive blood clotting and DVT?

  • ATX

    Any recs for a Dr in Austin, Texas that would be open to prescribing Clomid?

  • Brian M

    Any thoughts on Dr. Mark Gordon and his use of low dosage T with chlomid?

  • DHooves

    Are there risks to taking a low dosage of Clomid for many years? (Like 25mg every other day). Could taking Clomid continuously negatively effect a male’s ability to have children in 5, 10, 15 years? Can Clomid cause an attenuation of endogenous LH production? (Meaning, will the brain readjust to the lower perceived estrogen levels)

  • JCK

    Can Clomid cause gyno? What to do if so?

  • Jack Cole Dallas, TX

    Can clomid cause negative feedback in loop in time?

  • SHJ

    Can clomid cause or contribute to prostatitis / prostate inflammation? Would that explain a rising PSA and Lower fPSA with negative biopsy? Both decline after stopping clomid for a couple of months.

  • LK

    can Clomid have a beneficial effect on low RBC, Haemoglobin and WBC counts?also what effect does it have on creatinie levels? many thanks for your excellent website and responses

  • Paul

    Can Clomid trigger a heart attack? I started clomid and then I felt chest discomfort so I had to stop it. Dr. Miller: I haven’t heard of that reaction but any side-effect is possible with any medication. Depends also on your underlying health.

  • Paul Walsh

    Can I ask, have you had the occasion to hear of Clomid use causing too higher oestrogen levels and subsequent weight gain. Especially fat around the stomach?

  • JB

    Can you recommend a clinic or Dr in the San Antonio area who knows about and would prescribe Clomiphene Citrate (Clomid)as a low testosterone treatment program?

  • mario

    can you refer anyone in toronto canada

  • Daniel W

    Can you take an AI and clomid together? Dr. Miller: Yes.

  • Charles M

    Can you take hcg and clomid together

    Ive been doing juice hard for over 10yrs and never did any kind of clomid/hcg nothibg

    Fast forward im 40 and got married and wants children so i came off everything and my body turned off completely i cant even get errection

    Im seeing dr who prescribed me hcg and although i had lil excitement it was short lived and i have clomid and people telling me to take i just want to be sure and would appreciate any help im at a loss and feel broken

    As i cant just take test as that would fix errection but kill idea of children so im looking for help thank you

    Please im loosing my mind

  • sammie

    clomid affected my left leg and arm and caused seizures. I can walk but still feel the pain, what should I do? Dr. Miller: Go see your doctor.

  • Vis8

    Clomid enabled us to have our second son.

  • Talia

    Clomid is essentially hCG. Leydig cells in the testicles will die over time. So with the use of either hCG or clomid you are not looking at long term benefits. As the leydig cells die, so does your ability to produce testosterone. This is a temporary fix at best.

    Dr. Miller: Clomid is nothing like hCG, however it does stimulate LH which is similar to hCG. Although it is true that Leydig cells do decline in function with the aging process, in many elderly men they function without problem. In fact, a very common cause of low testosterone in aging men is actually Secondary Hypogonadism, not primary hypogonadism, meaning that the Leydig cells which produce testosterone are functioning well. In conclusion, I would say that although HCG or Clomid treatments may be temporary, “temporary” in these situations often means 10-50 years, depending on when treatment is initiated. Not a treatment window to dismiss or belittle.

  • sayed

    Dear Doc,

    Does rapid and fast sperm motility could be treated? Sperm head defect is almost 83%, any chance to improve this? Could you advice?

  • Kiran Krishnakumar

    Dear doctor hopefully you can reply to this comment. I had a loss of libido and was worrying and checked my testosterone levels. It was around 350..i am only 21 and this is very low. I used steroids without knowledge when I was 19.Will clomid work for me. It’s been 2 years since I’ve touched any steroids still my testosterone levels are so low. Help please

  • John

    Dear Doctor Miller, i had used steroids before one year and now my testosterone levels are very low 300. Also i have azwospermia and i had a surgery for that because i had varicocele on the left testical. Would can i do to increase my test levels? I have bad mood, low libido low energy and depression. Thank you.

  • Joe R.

    Dear Doctor Miller: I was taking 12.5 mg of Clomid for about two weeks (I had taken it before) on prescription from my doctor, and it was helping to boost my testosterone level. However, I started to have symptoms of constant lower bladder pain (or originating from my prostate, not certain). Can Clomid have negative effects on the prostate or bladder in that short period of time?

  • ray

    Dear doctor my test level is 480 i am 40 years old and ingood shape but i would like to get my test levels to the 800 plus.I do everything naturally to do this ..will clomiphen work on the nongonadal male to optimize levels

  • Samuel

    Dear Doctor, I’ve been on testosterone injections as well as HCG injections. I’ve been diagnosed with hypogonadotropic hypogonadism. The testosterone injections did not work so well to elevate the T levels but the HCG injections did work well. Ive been off the HCG injections now for about 2 months and the T levels have started to drop off again. Will beginning treatment with Clomid help my situation even though I have been on the testosterone and HCG before? Many thanks for your help. Dr. Miller: Yes, Clomid can help, even in men who have used testosterone or HCG in the past. Good luck!

  • jojo

    dear doctor, i was tested foe spermcount and it was 18,000 000 000 which mild low sperm count, can i start taking clomid

  • Moe

    Dear Doctor,

    I have performed TESE surgery 4 months ago and I have signs of low testerone caused by the loss of some testes tissues. I am aware that things will become normal after a while but as the symptoms I have are disturbing can Clomid accelerate the process of increasing testerone levels to normal? My doctor asked me to try Arimidix which I did not like due to its side effects and my e2 levels become low. Appreciate your advise.

  • Moe

    Dear Doctor,

    I have performed TESE surgery 4 months ago and I have signs of low testerone caused by the loss of some testes tissues. I am aware that things will become normal after a while but as the symptoms I have are disturbing can Clomid accelerate the process of increasing testerone levels to normal? My doctor asked me to try Arimidix which I did not like due to its side effects and my e2 levels become low. Appreciate your advise.

  • yasin

    dear doctor,

    I was very interested by your article here as I think I may be experiencing low T. I am an 18 year old male with Testosterone levels at 4.8 ng/ml (normal range 2.6-8.7) and very low FSH (1.8 mIu/ml) and LH (2.9 Iu/L) I don’t understand much about all this but I do understand my symptoms which are erectile dysfunction, low libido, pain in the penis shaft and testicles and also what seems to be the beginning of gynécomastia. I believe the problem has been brought on by the popular hair-loss drug, Finasteride which I took for only three days then stopped about a month ago. my situation has been getting worse every day for the last two weeks and I’m just very worried. I have mood swings and sometimes it’s hard for me to sleep. I have however put myself under a lot of stress because of all this, I am very worried and have that “butterfly in the stomach” feeling almost all the time. Unfortunately I did a bit of research and found something called post-Finasteride syndrome or PFS which seems to include all my symptoms. knowing about this and reading that it will never go away has certainly not helped. I was also tested for PRL which seems to be just in the upper 30% at 19 ng/ml (normal range: 3-25) so my questions are A.Do you think I actually have PFS (which is a form of secondary hypogonadism) and do you think it’s actually possible I got it after three days? or do you think my mind is playing tricks on me? B. do you believe that clomid could help my situation? if so how long do you expect I should take it? C. Do you think it’s possible that all my symptoms are stress-related as my parents keep telling me? D. I’ve started taking fish oil and adjusting my diet in a way that helps increase T levels but do you think the low FSH and LH can be helped as well? E. I’ve already seen a urologist and I have another appointment very soon. should I ask him for more tests? what should I be tested for? should I ask him for Clomid? should I ask for referral to an endocrinologist? F. do you think intervening with drugs like clomid at this stage will help in the long term?

    I greatly appreciate your reply. I am very very worried and really don’t know what to do. as you can imagine, being only 18, the thought of becoming impotent is destroying me. your advice will be greatly valued. Dr. Miller: Sorry about your situation. Yes, unfortunately, post-propecia syndrome is a possibility. Clomiphene may help.

  • JW

    Dear Doctor. Thank you for the clear article. Reading various clomiphene studies I see that some use 25mg daily and others 50mg 3x pw or 50mg every other day. Given that the overall dose is similar/identical, does this make any difference? Also, is there a preferred time in the day for taking clomid?

  • Mike

    Dear Dr Miller : please my Testo total =10.2nmol/L , S-Follitropin (FSH):3.8 U/L , S-Lutropin(LH)4.8 U/L , S-Prolactin 7.8ng/ml. Count = 15mill , 20% Active, 70% normal etc. Please Is it okay to take Clomid too? 25mg or 50 mg daily ?Been trying for three years with my wife. i never used any Testo injection. I only tried a supplement which seemed to work in 2013 , took my count to 38million, 60% was active with same 70% normal after bout 8mths use.count dropped when i stopped using the supplement.Thank you in advance

  • muste

    Dear dr miller as my doctor told me

    Clomid of in early maturation arrest spermatogesis, your comment please

  • saleem suliman

    Dear Dr Miller i wanted to ask you that if supposedly we take test enth injections and usually they store more water in the body can clomid remove excess water from the body or is it possible to use test and clomid together? Dr. Miller: You need to speak with your personal doctor.

  • Rob T

    Dear Dr Miller, A google search on “low libido with clomid” will reveal a large magnitude of patients experiencing significant libido reduction and ED with clomid. In many forums clomid has been defined as “A libido killer” nevertheless it definitely increases T level. I understand from my research that this is a very common side effect but there is no clear justification. Most of the patients are seeking clomid to enhance their sex life but it looks like clomid is working against it.

    I am sure you have researched this subject. Would you please share your opinion.

    Thanks. Dr. Miller: This is not my experience, but that may be because I follow estradiol levels and treat high estrogen levels. If estrogen levels are too high that could reduce libido.

  • mackie

    Dear Dr Miller, doctor prescribed clomid for me and my wife along with dose of vitamins C, E,B complex. we were trying to have baby for almost 5 years now. how frequent should the check up for sperm analysis? I already finished 2 clomid packs. Thank you. Dr. Miller: It can take two-three months.

  • Andy S

    Dear Dr Miller, How many months/years can I keep taking Clomid 50mg daily?

    Is it better to take 25mg twice daily or 50mg once daily?

  • kevin

    Dear Dr Miller, I have been using clomiphene about 1 year to raise my T score which it did, my girlfriend got pregnant also, is there any risk to the baby due to the medication?

  • Rajesh

    Dear Dr Miller, myself and my wife we were trying to have baby since last 3 yrs but no success. Last month i went to doctor and had my FSH,LH,T and SA tests done. FSH – 6.26 uIU/ml, LH – 4.22 uIU/ml, T – 3.43 ng/ml. Sperm count was 3.8 M/ml. Doctor told me that LH and T are normal where as FSH is high. He suggested me to take clomid 25mg daily to increase my sperm production . After 1 month , i had done my SA tests again . i expected sperm count to increase but instead i found out that my sperm count has actually decreased to 1.7 M/ml. Pls help me doctor

  • Rajesh

    Dear Dr Miller, myself and my wife we were trying to have baby since last 3 yrs but no success. Last month i went to doctor and had my FSH,LH,T and SA tests done. FSH – 6.26 uIU/ml, LH – 4.22 uIU/ml, T – 3.43 ng/ml. Sperm count was 3.8 M/ml. Doctor told me that LH and T are normal where as FSH is high. He suggested me to take clomid 25mg daily to increase my sperm production . After 1 month , i had done my SA tests again . i expected sperm count to increase but instead i found out that my sperm count has actually decreased to 1.7 M/ml. Pls help me doctor

  • James

    Dear Dr Miller,

    Thank you for a very informative website.

    2 questions please.

    1. In your study on this site of the efficacy of long term use of clomid, what dosages were given to the patients and was this dosage altered over the 3 year period?

    2. You mention the benefit of clomid as an alternative to trt. My current endo has me on 50mg clomid and 1% trt simultaneously. The goal is to prevent infertility. I realise you cannot provide personal medical advice, but my question is whether – in your experience – clomid does assist with preventing infertility and prevent the natural cycle from shutting down when used in combination with transdermal trt? Ie – will the trt reduce the efficacy of clomid in terms of the preferable benefits that you describe on your site?

    I am based in London and will be in the US in February ’15 – if possible I’d like to make an appointment to see you when I’m there. I need to make the best decisions I can in the interim and my experience with a whole series of GPs, endos and uros in the UK with regards to trt is that they fall far behind optimal guidelines in the US and elsewhere.

    Thank you for your time!


  • Jay Volker

    Dear Dr miller. Due to Low T some years ago I have experienced loss of libido and had some serious ED problems. It really has been terrible since. I am literally afraid to have sex. My recent testosterone level is 663 which my doc says is pretty good for a 30 year old. I do not get morning erections and cannot achieve an erection in a sexual encounter. My question is will taking clomid possibly raise my test level high enough in order for me to increase my libido?

    I am really scared. I finally met the woman I want to spend my life with and I know this is going to affect my chances. Im thirty years old and lost a relationship due to this already.

    Can a higher test level really bring me back to healthy sexual activity? Could higher test be the solution. My doctor has examined my penis physiology and said everything is fine. He cant seem to understand what is the probem. Please Dr miller your insight will be helpful.

  • Paul Walsh

    Dear Dr Miller. Im yet another patient with very low testosterone and low libido. Can I ask is it ever advised to take CC with an anabolic steroid? Thank you.

  • Matt

    Dear Dr Miller. let me start of saying I’ve used anabolic steroids for about 3 years. I have discontinued use of anabolics for about 5 months now. My test seems low and I’m having problems with my sex drive. I’ve taken Clomid in the past and it worked for me. I just need to know if when I stop using Clomid will my test go back down? Please help me find a remedy

  • Matt

    Dear Dr Miller. let me start of saying I’ve used anabolic steroids for about 3 years. I have discontinued use of anabolics for about 5 months now. My test seems low and I’m having problems with my sex drive. I’ve taken Clomid in the past and it worked for me. I just need to know if when I stop using Clomid will my test go back down? Please help me find a remedy

  • Ross

    Dear Dr Miller.

    This has been such a helpful and interesting read, if only there were more Doctors like you around.

    I am 23 and 14 months ago i ran a Steroid Cycle of Test and Tren, it was a very silly idea and have paid the price ever since. for 8 months i was reliant on Viagra and even then struggled to maintain and erection and ejaculate. Ran 25MG chlomid after my cycle and that was it. I have done a lot of reading and since then have found out that Tren is incredible harsh on the body and can also increase Prolactin Levels, resulting in a low Libido. I have a very low libido and feel it is all due to low test and high Prolactin. Due to it being such a long time ago, I am going to take HCG to kick start my LH and then run Chlomid to help produce Testosterone. I understand you can not give any medical advise, but I was wondering are there any drugs that work well with Chlomid to reduce prolactin that I could read up on and then discuss with my doctor? Appreciate any advice as I am only 23 and do not want to have to rely on Viagra for the rest of my life.

  • Ross

    Dear Dr Miller.

    This has been such a helpful and interesting read, if only there were more Doctors like you around.

    I am 23 and 14 months ago i ran a Steroid Cycle of Test and Tren, it was a very silly idea and have paid the price ever since. for 8 months i was reliant on Viagra and even then struggled to maintain and erection and ejaculate. Ran 25MG chlomid after my cycle and that was it. I have done a lot of reading and since then have found out that Tren is incredible harsh on the body and can also increase Prolactin Levels, resulting in a low Libido. I have a very low libido and feel it is all due to low test and high Prolactin. Due to it being such a long time ago, I am going to take HCG to kick start my LH and then run Chlomid to help produce Testosterone. I understand you can not give any medical advise, but I was wondering are there any drugs that work well with Chlomid to reduce prolactin that I could read up on and then discuss with my doctor? Appreciate any advice as I am only 23 and do not want to have to rely on Viagra for the rest of my life.

  • Mr. D

    Dear Dr Miller: Allow me to ask a question. I was diagnosed with low T. Readings were 159 and 240. I first started with a testosterone cream but my body didn’t absorb it as well or quickly. I then went to injections. My t levels were 794, 856, and now 1166. But now that my T levels are up, I’ve noticed some difficulty with erections again. My estradiol level has been 41. 38, 33. I know that is still within range, but is it possible that my body is sensitive to estradiol and that those numbers are too high for me, even though they are in the upper normal range? This is the only thing I can think of that has made my sex drive inconsistent. The doc has suggested arimidex. I could either lower my t dose (I get 1 cc a week), or take arimidex. Your thoughts? By the way, can a high estrogen level nullify the effects of cialis?

    Frankly, I’d rather not be taking anything of these things. I am wondering what would happen if I stopped the T injections and try HCG or clomid to stimulate my natural T production. I know you can’t give medical advice but any thoughts would be appreciated. Should I have some type of blood or hormone test done to see if something else is going on? If so, what kind of doctor would do that?

  • Ferre

    Dear Dr Miller: I’m 50. I took 25mg Clomid daily for six months. It jacked up my count from 340 to 830, and restored my libido –worked wonders. I stopped because I started ejaculating pink. It cleared up after a week or so and I went back to low dose Clomid but the pink came back again. Is it normal for Clomid to cause this? I’ve been off it for 4 months now and miss it. Is it also normal for post-Clomid volume of ejaculate to drop significantly?

  • AK

    Dear Dr Miller: Thanks for this great article and for taking the time to answer comments! I’m 34, and had secondary hypogonadism, with low LH & FSH, T-levels in the range 100-200 ng/dL and high estrogen (around 60 pg/mL). Two months ago I was prescribed a course of clomid (first month 12.5 mg ED, later upped to 25 mg ED), plus for the last month also anastrozole .25 mg EOD. I’ve taken clomid for over 2 months now; my testosterone came out 623 ng/dL this time round, estrogen at 39 pg/mL. Overall I definitely feel better than I used to, but libido is rather weak. No spontaneous erections, weak morning wood, erections aren’t that strong even at peak of arousal. Is this something that will resolve itself over time? Prolactin’s a bit high, if that’s significant: 16.93 (ref range 2.10-17.70). Also, having excessive vivid dreams because of which sleep doesn’t feel restful. Would appreciate your comments.

  • mazen abdalsalam

    Dear dr millir iam dignosed as sertoli cell only syndrom by test biopsy test 300ng fsh high more than normal lh upper normal prolactin upper normal l think I have symptoms of low test is clomophin of benefit thanks

  • muste

    Dear dr mOllerton as my doctor told me

    Clomid of in early maturation arrest spermatogesis, your comment please

  • DK

    Dear Dr, I (30 yrs male) was diagnosed with

    Low T – 278 ng/DL (300 – 1080 range) six months back and doctor did additional blood works as below

    LH 8 mIU/ml (2-9 range),

    FSH – 14.4 mIU/ml (1.4 – 18.1 range),

    Estradiol – 21 (0 – 42 pg/mL),

    Prolactin – 11.8 (2.1 – 17.7 ng/mL)

    Thyroxine, Free – 1.2 (0.8 – 1.8 ng/dL)

    Sperm count – 96.4 millions with 57% of motility.

    my DH prescribed clomid 25 mg every day and i did checked my T level after month use of clomid its increased to 542 ng/DL. However i stopped using them for a month again and i am experiencing poor erection, lack of libido and i checked my FSH & LH again which is in high range LH – 13 (2-9 mIU/ML) & FSH – 21.7 (1.4 -18.1 mIU/ml range) and i am waiting for T level results to come.

    would like to know the reason for poor ED, libido and why my FSH & LH increased? i haven’t measured the Estodrial level and i am 5’9 with (170 lbs). Plz suggest.

  • Ray A.

    Dear Dr. I have done the injections and my test. will not increase higher than 165. My dr. will not put me back on because my prostate in somewhat increased and my psa is 5.25 due to risk of cancer. He took samples from my prostate and found no cancer. Will clomid get my test. by to normal…….help. Dr. Miller: Hi Ray, Yes, Clomid may increase your testosterone, it depends on other blood testing. Your would need to monitor for change in PSA. Please email me if you would like to become a patient.

  • Paull

    Dear Dr. Miller – I’m 25 and 10 years ago I had one testicle removed (due to torsion) and I suffer from low libido which, I can guess, is due to primary hypogonadism. However, my endoctrinologist has recently prescribed me Clomiphene. My question is – should I be worried that due to this Clomiphene treatment, my remaining one testicle can be “overload” and (in any sense) damaged by high LH/FSH? Is there any “border” of how much testosterone one testicle can produce? Thank you in advance!

  • Todd

    Dear Dr. Miller

    I am a 52 year old male with 237 Testosterone level

    I asked my internist to check my LH(2.4) and FSH(2.5) ad both are low end of normal.

    He thought it ma be a Pituitary tumor but just finished a MR and it was negative.

    MY Cotrisol(11.6) and Prolactin (7.3) levels are normal according to him.

    I asked him to take DHEA-S and they are low at(65.4) also have low SHGB at (12.3).

    He now wants to put me on Androgel which is what figures.

    Based on these numbers am I better candidate for Clomid?

    He ask the Endocrinologist in is practice and he told him i was better for younger males with fertility issues as well.

    I have looked into costs of bioidentical hormones and would be hard to financially right now.

    Would trying Androgel at least be an acceptable solution?

    Thanks you!

  • gurumeditation

    Dear dr. Miller

    For 5 years I’ve been on treatment for gender identity disorder. I’ve been on androcur and estrogen which obviously caused testicular atrophy and erectile dysfunction. 6 months ago I stopped all treatment. Now I have some recovery (erections and some testicular regrowth) but it’s still not as it used to be (energy level suffering mostly) before the hormone treatment. Do you think in my particular case Clomid could revive my testes? Your advice is most welcome

  • Alexandra V.

    Dear Dr. Miller, me and my husband have been trying to conceive for 2 years now. We managed to get pregnant 5 years ago and he was diagnosed with low sperm count. A few few months ago he got tested tested again and now they are not even present. We have not yet seen a doctor for him, he’s very skeptical about doctors. I also think he’s a bit embarrassed and ashamed about discussing his condition. He’s tried fertile aid and it didn’t work at all. His mood is out of control and he barely sleeps and has a very difficult time putting on pounds. Can taking clomid help this/ our situation? If so how long will he have to be on it? Thanks in advanced for your help. Dr. Miller: It depends on the cause of his low sperm count. He needs a comprehensive evaluation. Clomiphene may help, depending on the cause. Good luck.

  • Raphael D’Souza

    Dear Dr. Miller, I am a 36 yr old Male, have secondary hypogonadism due to Hyperprolactinemia. Further MRI Scans show a macroadenoma of the pituitary gland of size 3 cm x 3 cm x 2.8cm. I am on Dostinex 0.5 mg (Cabergoline) since the last 7 months and my prolactin levels have come down to the normal range but my testosterone is still very low. Also because of the high prolactin earlier I have gynecomastia. Kindly advise me any and/or of the three. Clomid/ Nolvadex/ Arimidex.

  • Brad

    Dear Dr. Miller, I took clomid 50 mg for 1 month and my sperm count fell from 40m to 8m. Does clomid have side effects of lowering sperm count in some cases while my T levels are same before and After one month clomid course. Or Is 50mg on the higher side for men

  • GG

    Dear Dr. Miller, I was treated for vericole vein (surgery) and low testosterone (25mg Clomid 3 days/week) in hopes of increasing my sperm count and quality. 3 months after taking clomid and 2 months sense surgery, my testosterone is in low 500, but my estrogen went up from 30 to a 100 within 3 months. My doctor is prescribing medicine to counter this, but I am wondering about your thoughts on connection between vericole removal, clomid and increase in estrogen. I am young, late twenties, and in good shape – exercise regularly and I eat healthy.

  • GG

    Dear Dr. Miller, I was treated for vericole vein (surgery) and low testosterone (25mg Clomid 3 days/week) in hopes of increasing my sperm count and quality. 3 months after taking clomid and 2 months sense surgery, my testosterone is in low 500, but my estrogen went up from 30 to a 100 within 3 months. My doctor is prescribing medicine to counter this, but I am wondering about your thoughts on connection between vericole removal, clomid and increase in estrogen. I am young, late twenties, and in good shape – exercise regularly and I eat healthy.

  • SYED.

    Dear Dr. Miller, My T was 50.6nmol/L in 2010 and 10.9 nmol/L now , had couple of injection 2yrs ago. don’t know whats the cause of low T,though have low libido.I am 47 not on any regular medication ( occasional Aspirin),can I take Clomid to raise T level and how long should I continue. please tell if any interrupted or short (on and off)course of clomid. thanks. Dr. Miller: You have to find out if low T is due to primary or secondary. I cannot give personal advice here.

  • Matt

    Dear Dr. Miller, since 2y ago the gen-test diagnostic me The Klynefellter syndrom (i have XXY chromosone), too low TST 2.0 nmol, all syndroms that You wrote upside of this text and also male fertility. Some doctors (urologers), recommended to me endogene gonadotropin (HCG), because in Balkan states (Romania, Bulgaria, FYROM) this preparates have very positive effects, but in the middle of EU, nobody cant help me. Then I search on the web, and I found an article about Clomiphene Citrate in one Czech magazine about Health.

    My question is: Do You think, that it (Clomiphene Citrate) could help me with my problems about TST and fertility?

    Thank You for Your opinion.

  • sajjad ashraf

    dear Dr. Miller,

    My name is Mr. sajjad ashraf,I am a retired school teacher and live in south asia (Pakistan).since the last 7 years I have been suffering from erectile dysfunction,impotence,infertility and lack of libido,but at the same time I have also been suffering from BPH (banign prostatic hyperplasia).I consulted a urologist who suggested a surgery but I did avoid.a month ago I visited your site and started taking clomid (clomiphene citrate) as a self medication,one tablet of clomid 50 mg daily and after 27 days I felt a reasonable relief in BPH as well as ED,impotence,infertility and lack of libido.So far I have not made any test of low testosteron level,but I am sure all these symptoms were arisen because of low testosteron level and harmonal imbalance in my body and now after taking 50 mg tablet of clomid my symptoms started reducing day by day as now I am improving ED and libido as well as I have to only once go to urinate at night ,while last year I had to go to urinate 5 or 7 times at night.

    As I belong to lower middle class and can not accomodate expencive medications,therefore it is requested to please advise me what further steps should I take to continue clomid and for how long should I take it.At present, my age is 54 years. kind regards sajjad ashraf

  • Francis

    Dear Dr. Miller,

    I am taking clomid for almost two months now. I am taking it every morning and evening. My question is I forgot to take my clomid last night. Will it be ok to take 2 tablets to make up for last night dosage. Thanks!

  • Paul D

    Dear Dr. Miller,

    60yo WM overweight hbp otherwise good.

    While on Androgel therapy T went up to 1200. Switched to Clomid, was 72 last week. We have doubled Clomid to 50mg QD. Thanks, P

  • Adam

    Dear Dr. Miller,

    I am a 30 years old man who has 13 nmol/L total testosterone and other symptoms like anxiety, depression, lack of motivation, loss of muscle mass since my teenage years, I have suffered a lot of.

    I would like to start Clomid but I have a grade II (in my opinion grade III) varicocele on the left side and I am thinking about microsurgery.

    Is it possible that there is relationship between low T and varicocele?

    Can the repair of varicocele raise significantly my testostreone levels?

    Thank you for your answer.

  • Rebecca

    Dear Dr. Miller. My husband is 40 years old and has never had children. We have been trying to get pregnant the last 6 months and recently found out that his sperm count is at 0. He has been on TRT for about a year and a half because his levels were low (around 200). His doctor took him off Testosterone and prescribed him 50mg of Clomid. Should he also be taking HCG to help with fertility?

  • Kovacs S

    Dear Dr. Miller. My problems started about 3 years ago. I made a wrong steroid use and after that my hormon levels got unbalanced. I had mood changes, low energy level, lower libido, but no erectic disfunction. I went to an endocrinologist who checked my level, T was in the lower range of normal, Estrogen 3x time the normal, prolactin normal, LH and FSH are normal but was in the lower range. He put me on clomid use for 3 mounths and fter that my testosteron went too high, upper the normal range. Estrogen went back to normal. Lh and Fsh was not checked. We waited 3 mounths, then he checked hormon level again, my estrogen was perfect, prolactin perfect, LH perfect , fsh not changed but my testo lvl got lowered again(normal but pretty low for a 28 y old who train almost every day). My question is only that if i have normal LH level, normal estrogen level and clomid can stimulate leydig cells than i have no problems with my leydig cells or my “balls”, right?

  • TonyD

    Dear Dr. Miller:

    I have a question regarding estradiol levels when taking Clomiphene. I’m a 44 year old male, 6’1”, 174 lbs., with a diagnosis of secondary hypogonadism due to hypopituitarism. My physician started me on clomiphene, 25 mg, every other day.

    My baseline lab results:

    FSH: 5.2 mIU/ML

    LH: 1.6 mIU/ML

    Prolactin: 3.0 NG/ML

    IGF-1: 182 NG/ML

    T (Total): 214 NG/DL

    SHBG: 29.3 NMOL/L

    T (Free): 40.1 PG/ML

    T (Bioavailable) : 110.8 NG/DL

    Albumin: 5.1 G/DL

    Estradiol (ultrasensitive): 27.2 PG/ML

    Dihydrotestosterone: 25 NG/DL

    PSA: 1.0 NG/ML

    After 15 days on clomiphene, 25 mg, every other day:

    FSH: 7.9 mIU/ML

    LH: 3.9 mIU/ML

    Prolactin: N/A

    IGF-1: N/A

    T (Total): 483 NG/DL

    SHBG: 27.0 NMOL/L

    T (Free): 76.3 PG/ML

    T (Bioavailable) : 157.0 NG/DL

    Albumin: 4.5 G/DL

    Estradiol (ultrasensitive): 65 PG/ML

    Estrone : 51 PG/ML

    Dihydrotestosterone: N/A

    PSA: N/A

    After 45 days on clomiphene, 25 mg, every other day:

    FSH: 8.6 mIU/ML

    LH: 5.0 mIU/ML

    Prolactin: 2.7 NG/ML

    IGF-1: N/A

    T (Total): 784 NG/DL

    SHBG: 23 NMOL/L

    T (Free): 153.7 PG/ML

    T (Bioavailable) : 322.8 NG/DL

    Albumin: 4.6 G/DL

    Estradiol (ultrasensitive): 17.0 PG/ML

    Estrone: 22.0 PG/ML

    Dihydrotestosterone: 46 NG/DL

    PSA: 1.3 NG/ML

    Zinc: 85 MCG/DL

    Copper: 104 MCG/DL

    Ceruloplasmin: 30 MG/DL

    Is it typical for estradiol levels to fluctuate so wildly (~400%) when starting Clomiphene? I’m wondering if one of there may possibly be a lab error.

  • TonyD

    Dear Dr. Miller:

    I have a question regarding estradiol levels when taking Clomiphene. I’m a 44 year old male, 6’1”, 174 lbs., with a diagnosis of secondary hypogonadism due to hypopituitarism. My physician started me on clomiphene, 25 mg, every other day.

    My baseline lab results:

    FSH: 5.2 mIU/ML

    LH: 1.6 mIU/ML

    Prolactin: 3.0 NG/ML

    IGF-1: 182 NG/ML

    T (Total): 214 NG/DL

    SHBG: 29.3 NMOL/L

    T (Free): 40.1 PG/ML

    T (Bioavailable) : 110.8 NG/DL

    Albumin: 5.1 G/DL

    Estradiol (ultrasensitive): 27.2 PG/ML

    Dihydrotestosterone: 25 NG/DL

    PSA: 1.0 NG/ML

    After 15 days on clomiphene, 25 mg, every other day:

    FSH: 7.9 mIU/ML

    LH: 3.9 mIU/ML

    Prolactin: N/A

    IGF-1: N/A

    T (Total): 483 NG/DL

    SHBG: 27.0 NMOL/L

    T (Free): 76.3 PG/ML

    T (Bioavailable) : 157.0 NG/DL

    Albumin: 4.5 G/DL

    Estradiol (ultrasensitive): 65 PG/ML

    Estrone : 51 PG/ML

    Dihydrotestosterone: N/A

    PSA: N/A

    After 45 days on clomiphene, 25 mg, every other day:

    FSH: 8.6 mIU/ML

    LH: 5.0 mIU/ML

    Prolactin: 2.7 NG/ML

    IGF-1: N/A

    T (Total): 784 NG/DL

    SHBG: 23 NMOL/L

    T (Free): 153.7 PG/ML

    T (Bioavailable) : 322.8 NG/DL

    Albumin: 4.6 G/DL

    Estradiol (ultrasensitive): 17.0 PG/ML

    Estrone: 22.0 PG/ML

    Dihydrotestosterone: 46 NG/DL

    PSA: 1.3 NG/ML

    Zinc: 85 MCG/DL

    Copper: 104 MCG/DL

    Ceruloplasmin: 30 MG/DL

    Is it typical for estradiol levels to fluctuate so wildly (~400%) when starting Clomiphene? I’m wondering if one of there may possibly be a lab error.

    Dear Dr. Miller:

    I have a question regarding estradiol levels when taking Clomiphene. I’m a 44 year old male, 6’1”, 174 lbs., with a diagnosis of secondary hypogonadism due to hypopituitarism. My physician started me on clomiphene, 25 mg, every other day.

    My baseline lab results:

    FSH: 5.2 mIU/ML

    LH: 1.6 mIU/ML

    Prolactin: 3.0 NG/ML

    IGF-1: 182 NG/ML

    T (Total): 214 NG/DL

    SHBG: 29.3 NMOL/L

    T (Free): 40.1 PG/ML

    T (Bioavailable) : 110.8 NG/DL

    Albumin: 5.1 G/DL

    Estradiol (ultrasensitive): 27.2 PG/ML

    Dihydrotestosterone: 25 NG/DL

    PSA: 1.0 NG/ML

    After 15 days on clomiphene, 25 mg, every other day:

    FSH: 7.9 mIU/ML

    LH: 3.9 mIU/ML

    Prolactin: N/A

    IGF-1: N/A

    T (Total): 483 NG/DL

    SHBG: 27.0 NMOL/L

    T (Free): 76.3 PG/ML

    T (Bioavailable) : 157.0 NG/DL

    Albumin: 4.5 G/DL

    Estradiol (ultrasensitive): 65 PG/ML

    Estrone : 51 PG/ML

    Dihydrotestosterone: N/A

    PSA: N/A

    After 45 days on clomiphene, 25 mg, every other day:

    FSH: 8.6 mIU/ML

    LH: 5.0 mIU/ML

    Prolactin: 2.7 NG/ML

    IGF-1: N/A

    T (Total): 784 NG/DL

    SHBG: 23 NMOL/L

    T (Free): 153.7 PG/ML

    T (Bioavailable) : 322.8 NG/DL

    Albumin: 4.6 G/DL

    Estradiol (ultrasensitive): 17.0 PG/ML

    Estrone: 22.0 PG/ML

    Dihydrotestosterone: 46 NG/DL

    PSA: 1.3 NG/ML

    Zinc: 85 MCG/DL

    Copper: 104 MCG/DL

    Ceruloplasmin: 30 MG/DL

    Is it typical for estradiol levels to fluctuate so wildly (~400%) when starting Clomiphene? I’m wondering if one of there may possibly be a lab error.

  • Tadele B.

    Dear Dr. Miller: As my doctor told me I have cause secondary hypogonadism problem and he put me on Clomid 50mg. As soon as I start i feel stomach, vision & pelvic pain but I continued for 45 days mean while I do not feel penis weak (not erect) Libido. what do you advice me my doctor I am sorry to say he can not correct the problems. Dr. Miller: You need to find a doctor who can help you. Sometimes HCG is necessary instead of clomiphene, depends on the cause of your hypogonadism and your individual response.

  • M. Osmak

    Dear Dr. Miller: I am taking cabergoline for elevated prolactin levels due to a begnin pitutatory tumor. i also have low test and low lh and fsh. we are trying to get pregrnant. if i took clomid would it interfere with the cabergoline that is used to lower prolactin levels? what dosages and length should one start off with?

  • Sam O.

    Dear Dr. Miller: Thank you for valuable information. You write that Secondary Hypogonadism can be caused by medication. Is it known if medication for BPH (flomax) can cause low T,?

  • Jerry M

    Dear Dr. Miller:I read your blog on Clomid some time ago and was impressed with how Clomid could help with a man’s testosterone production. I had been on andropause for low T. I was also on omeprazole and had been for a number of years. I researched omeprazole on the web and discovered that it could lower testosterone. I immediately quit taking omeprazole and that night and the next morning I had 5 “woodies.” I was amazed. I came to the conclusion that omeprazole had lowered my T production and the Doctor then put me on androderm to increase my T level. UNBELIEVABLE! I still wanted to try Clomid to increase my testosterone production. I asked my doctor to put me on Clomid. He joked that he was afraid I might end up having “twins” and denied my request. I found another doctor and he agreed to put me on 50mg for a month to see how I would do. I could tell right away that I felt better and had more strength. I took the pill every other day. I quit taking Clomid after I ran out of pills. I still had energy and strength. I was able to lift more weights. I had my testosterone checked after being off Clomid for 2 months. It was 440. Before that I could not get it above 300. I believe that Clomid “jump-started” my testosterone production just like you said it might. My production was non-existent because of androderm. I am 71 years old and I have a really great libido now. I am going to get another blood check in September and see where my T level is then. I can’t thank you enough for posting the information about Clomid on the internet. THANK YOU.

  • Kareem

    Dear Dr. Thanks for the great information. I want to seek you advice as well. I am 30 years old male, all my life had normal sex drive..until few years back had low desire without noticing, thought at first due to focusing on work life. After getting married a year ago i faced ED and low desire, after checking with Drs. I found by prolactin level high 60 ng/ml (range2.5-17) and found FSL/LH/ ( low normal while T total and free below normal (T-total was 1.1 range 2.4-8.3 ng/ml …free was 4.2 range 8.7-40 pg/ml)…. MRI showed microadenoma 8mm, I was advised to take dostinex which immediately showed great results in less than 2 month… ED was fixed, FSH increase to 4 miu/ml LH 3.5 mIU/ml, T-total 3 ng/ml T-free 16pg/ml and prolactin was suppressed below normal range…sperm count was 96 million/ml(total 228 million) in May 2013 and in Oct I also checked semen again sperm concent. was 80million/total 400 million. Month ago (JAN-14) I rechecked the adenoma and it was suppressed to 4mm.All is great till now but the weird thing that when I have redone my semen, the count of semen declined hugely to 16mill/ml (total 80 mill) with 50% motility…a huge decline from 80million/ml only in 4 month (normal range above 15mil/ml)…also the FSH and LH although within normal range they declined to FSH-2 mIU/ml (range 1.5-14), LH 1.8 mIU/ml (range 1.5-8), Total Test 2.7 (range 2.4-8.3), Free T 10 (range 8.7-40)…while desire and ED still looks normal….I am really confused Dr. and afraid that I am in declining trend and not sure what is happening? do you believe I need to take clomid or other HCG..I am keen to have good fertility as I do not have children yet…really appreciate your feedback. Thanks in advance. Dr. Miller: I’m sorry I can’t give personal medical advice here. However, in general, treating a prolactinoma doesn’t always reverse the secondary hypogonadism and HCG or clomiphene may be required, at least temporarily. Or suppressing prolactin longer and more may likely be tried first.

  • Waseem

    Dear DR.

    I am 19 year old male from pakistan and i have no facial hair. Because i have low testo. My total testo level is 237ngdl. Plzzz suggest me a treatment please otherwise i will be destroyed because my friends tease me due to no facial hair. Dr. Miller: Please go see Dr. Nanik Ram in Karachi. Testosterone level is not enough. You need more tests and physical exam for a decision. See this article: .

  • ankur

    Dear Dr., clomid increase fsh also in men and high fsh can cause low sperm count. then clomid causes infertility in male? Dr. Miller: I haven’t seen this. Actually the opposite. Clomiphene increases sperm count, and only causes high FSH if overdosed.

  • BAS

    Dear Dr.,

    Your commentary is extremely useful. I have tested quite low on T count (between 270 and 350) in 3 tests in 2013. The cause was idiopathic secondary hypogonadism; after approaching holistic ways to address it (including herbal supplements such as Maca Root and dropping 20 lbs, I have been able to raise T to 430-450). Concurrently, I also developed gynocomastea. I am still low on libido. In order to increase my T, I see my choices as Anastrazole (given my gyno), Clomid OR (less side effects than Anastrazole). I am even considering gyno surgery. Any comments on whether I should try clomid for 3 months and then consider surgery? I have a feeling that because I am out of the Low T danger zone, Clomid may reset my system after 3-6 months of use. However, I don’t want to risk more gyno. Appreciate your thoughts.

  • Tadele Bero

    Dear Dr.Dr. Miller: As my doctor told me I have cause secondary hypogonadism problem and he put me on Clomid 50g. As soon as I start i feel stomach, vission & pelvic pain but I continued for 45days mean while I do not feel penis weak (not erect) Libido. what do you advice me my doctor I am sorry to say he can not correct the problems.

  • Tereyll

    Dear Dr.Miller I have been prescribed clomid 50mg. I left the box in my car for 2 days temperatures were around 87deg outside. I know it says to store at room temperature.Could this blunder make the clomid ineffective.

  • Danny

    Dear Dr.Miller, i have low T levels, is there any doctor who you can suggest to treat this in Minnesota?

  • Mike

    Dear Dr.Miller, my blood tests show rather low free and bioavailable testosterone (in the first test both were about 40% lower than the minimum normal value, and 1.5 months later both were 55% lower), however total testosterone was in the middle normal range first time, and about 30% higher than minimum normal value in the second test. LH and FSH were normal first time (though LH was on lower limit), and we didn’t test them second time. Endocrinologist suggested testosterone replacement therapy right away, however I want to keep my fertility. Urologist actually suggested to try Clomid, if I don’t want testosterone…I’m wondering what you think, if Clomid can be any good in my case. I’m 33 years old, thin guy, go to the gym regularly, mostly eat healthy food. However, I did have sort of chronic liver conditions for 10 years or so (high ALT, AST and billirubin) – now their levels are normal.

  • Safeer Ahmed


    VOLUME: 4.0 ml




    TOTAL SPERM COUNT: 80 Million/ml

    Actively Motile: 50 percent

    Sluggish: 10 percent

    Non-Motile: 40 percent

    Pus Cells: Numerous

    R.B.C.s 02-03

    Please doctor tell me is my report is normal or not? if not then tell me some treatment to care it?

    Please…. please…..please….

    My email address is:

  • d

    dear sir, my sperm count is 8 mn/ml and doc prescribed me clomid 25mg for three month… will it help???

  • Greg

    Do you feel that ultra sensitive estradiol test is preferable to a standard estradiol for men?

    Thank you

  • Martin Brady

    Do you know any Doctors in the Philadelphia Area that share your views?

  • Don

    Do you know of a doctor in or around Atlanta that you could recommend? I was diagnosed with low T several years ago and hated using the topical gels so I just stopped. Getting worse now so I am hoping Clomid can help. Dr. Miller: Try Dr. Nicole Peoples.


    Doc, your article is very enlightening, however you failed to address the treatment of primary hypogonadism with chlomid and if it works or not.

  • Gary


    Have been relieved to read your impressive and nicely-balanced professional background–I like your approach! Was hoping to get an opinion about the return of testosterone to pre fatherhood levels, particularly in re. to the study by Gettler, McDade et. al. on decreasing testosterone in care-giving fathers. I strongly suspect my t levels have dropped since my wife became pregnant, and that those levels dropped further as I have spent most of the day caring for our wonderful 10 mo. old son. I am a healthy 50 yr. old man who married a wonderful 35 yr. old woman three years ago. I’m naturally muscular, hirsute, happily bald, and (apparently) quite fertile. I’ve never taken hormones of any kind. I’ve followed Barry Sears’ Zone diet since ‘96 and take highly purified fish oil and Vit. D3. My wife and I are quite close and I experienced strong couvade symptoms during her pregnancy, and our libidos dropped significantly. Now she’s on the upswing, but since the summer began (we’re both teachers) and I started spending the day w/ the boy, I’ve become depressed and have experienced muscle and joint pain (w/ libido close to nil). I’m seeing my GP this week for a physical and have an appt. w/ a doctor of integrative medicine as well. Cutting caffeine, dairy, and gluten have helped dropped weight quickly for both of us, which I understand is crucial for optimal Clomid efficacy. I have experienced anxiety and sleep problems w/ fatherhood and my wife’s post partum depression, but we’re doing a good job of working through these stressors and my sleep is improving. Questions (!?): Do you think my testosterone can return when I go back to work in the Fall? What’s your take on DHEA to help boost testosterone? Is a course of Clomid treatment likely to kickstart my hormonal processes back to pre fatherhood function without necessitating a lifetime of dependency on the drug? Thank you ever so much!

  • Larry W

    Doctor suggests clomid for me, but I am overweight, and she is concerned about aromatase – thus, she wants to put me on dose of natural progesterone, as well. She says this will help stop aromatization of testo. Correct? Thanks. Dr. Miller: One would need to lose weight soon, and take an aromatase inhibitor in the meantime. That’s what I recommend, in general.

  • Robert Giay

    Doctor, what do you think about Tamoxifen compared to Clomid? Some sites says they are similar in their effects and action others say they are not. Some says Tamoxifen has less sides and preferable over Clomid.I am really confused about this.


    Doctor, It seems to me that long-term exposure to suboxone drove my T level way down (almost below 100). I obviously had other issues given the initial need for suboxone in the first place but i was put on an unnecessarily high dose before i knew better. i am down to 8mg a day now. Anyway, several years later, after being “depressed” for well over a year, with no treatment taking, I self-diagnosed as low-T after watching some commercials on the tele. I was given the tests and put on Axiron. My T levels skyrocketed and believe me, the change was noticed; not only could I actually get out of bed and take a shower, I could focus, had motivation, etc, not to mention a significantly increased libido and the accompanying physical responses, etc. SO MY FIRST QUESTION WOULD BE, ASSUMING ONLY THE INFORMATION I HAVE GIVEN YOU, IS SUBOXONE THE MOST LIKELY CASE OF MY LOW T. Moving on, after half a year or so, a lot of my hair began to fall out and I have basically been trying to strike the perfect balance between one and two pumps ever since.

    I “discovered” Clomid several years ago and brought, to my first urology appointment, two reputable studies i found on Google Scholar testifying to its efficacy. The doctor looked at me like i was crazy and told me it was for fertility (women’s presumably). Anyway, I got an MRI that eliminated any physical cause for secondary hypogonadism, and everyone seems to think its that suboxone. What do you think AND, more importantly, can Clomid work if I am still taking Suboxone even though I am reducing my dose. I want to take as few meds as possible but I would prefer Clomid to Axiron for all the reasons explained in your essay, and which I have read about before. SO AGAIN, MY SECOND AND MAIN QUESTION IS WHETHER CLOMID WOULD WORK ON SOMEONE WHO IS TAKING SUBOXONE? Any helpful advice you can give me is greatly appreciated. Dr. Miller: Yes, any opiate can cause low T. Yes, clomiphene can help, but not necessarily.

  • Hady

    Doctor, the result of my test was 265 after 2 months of a steroid cycle. With this level, is it possible to make my wife pregnant? And should i take clomid? For how long? Any bad side effect of clomid use? Thank you. Dr. Miller: Read my article about side-effects. Possibility of pregnancy depends on sperm count, not testosterone level.

  • shah

    does alternate day clomiphine works?

  • dr kiro

    does testerone or androgen genrally must convert to estrogen to suppress hypothalamic GRH

  • john

    dr i am male 28 i had t level in 160 after taking clomid 50mg for 3 months it came to long it will stay on this level or when i need to go for next test??,thank you doc. Dr. Miller: It depends on a lot of factors. Studies show that after six months young men can try to wean off, in general. Everyone is different and you need to work with your doctor.

  • Scooter

    Dr Mille, I’m a 47yo man with secondary hypogonadism due to being Rx opioids for chronic pain, which is from having 2Spinal surgeries. The last one being a Fusion,too include hardware implanted. I can not stand to take these Meds,yet I don’t think I have any options. I’ve even been trying to useAll Natural herbs to see if that would work for chronic pain, not having much luck. Ok, so now I’m having all the symptoms of LowT along with other common symptoms. So,I would appreciate I feel out can tell med if this Is something that could help me? Other than my spinal problems, I am a very healthy guy. I just hate what the Morphine and Gabapentin is doing to me as a man. It’s taking away my maleness,I feel less of a man. I don’t want to ever try the BigPharma Testosterone, ESP with all the serious problems that I read and hear about. It is way too risky for me. Please,any information that could Help me would be Very Much Appreciated! HelpMePlease!

  • Adam

    Dr Miller – I am a 36 y/o male and recently had my testosterone checked due the presence of symptoms including fatigue and low libido. The result was 267 but they were concerned by an accompanying high FSH level and sent me for an MRI. The scan result showed what they called a .25″ “spot” on my pituitary. I was then referred to an endocrinologist and am now awaiting that appt. Is this something that can be typically treated with medication? I just want to get an idea of what is ahead of me.

  • Fun2drive

    Dr Miller

    Thank you for your time on this site. I am in excellent physical shape and had rad therapy for prostate cancer. I had my T checked and it is 404. E2 is high at 38 upper range is 42. I started taking Indolex DIM 300mg and will get my T and E2 checked in a few weeks. Trying to drive my E2 into the mid range. My urologist is aboard with helping me increase my T to a much higher number. I have noticed a great deal of difficulty getting muscle mass when exercising and too much emotions when I am typically not. I have Clomid but will not take it until I discuss it with my urologist. I am trying to target 700ish for T levels. I plan to use Clomid to do this with his approval. I also have smaller testis from the rad treatment and was planning to discuss HCG to get them back to normal size. Your site had educated me well

  • Jay V.

    Dr Miller, do u deal with international patients? Dr. Miller: Yes, please email me.

  • David C.

    Dr Miller, great article; I have read clomid 50mg plus Anastrozol 1mg are very toxic drugs for the liver. Is ok to take a natural liver detox while taking clomid + Anastrozol? – would clomid + Anastrozol be metabolized correctly by the liver under the effect of a natural liver detox ? – also, are ok to take vitamin D, probiotics and coconut oil ?

    Thank you so much!

  • J M

    Dr Miller, I have been diagnosed with secondary hypogonadism and have been taking testosterone in various forms (Testim, Testopel and IM testosterone) for about 26 months. Would clomid or HCG be effective for someone who has been on testerone for over two years? Aslo, which is more advisable: clomid or HCG? Thanks.

  • Jake

    Dr Miller,

    I am a 24 year old male who has been suffering with depression, low energy, and overall feeling awful for close to three years now. I had a testosterone reading done and it came back at 270 ng/DL. The doctor wanted to confirm the test, ordered another, and the results came back at 474 ng/Dl. Both tests were done in the morning. For both reading, my free testosterone was 11 pg/ml. I have not had morning nor nighttime erections for over two years now, and am completely impotent. My doctor tells me I’m in the normal range, prescribed me viagra and an antidepressant. I still do not feel right nor do I have a sex drive. How should I go about getting the help I need? Dr. Miller: Find another doctor. You can contact me. Send me an email.

  • Jon B.

    Dr Miller,

    Thanks so much for your information that you have posted. I have had low testosterone for a number of years (under 300 for at least 10 years), but it dropped from 259 down to 170 in about 18 months. At that amount, my doctor agreed to do something about it, but I had elevated red blood cells in the past (for no apparent reason — I suspect sleep related, but sleep study was not very helpful). Due to the red blood cell issue, the doc would not prescribe any exogenous testosterone treatment (which I agree with). I proposed clomid, and he agreed to try it, but had never heard of it (I provided a number of studies and references). Anyway, it worked. Total testosterone went from 170 to 822, free went from 11.8 all the way up to 184. However, I am having libido problems, gyno is starting, and my E2 is at 95. My doc does not know what to do. He did not feel comfortable treating me for these issues, and has referred me to a urologist. I cannot get in for at least three weeks. Any suggestion on finding a doctor in the NE FL area that might be familiar with using clomid? I am technically obese (down 20 lbs in 1.5 months, and am committed to losing weight long term, which should reduce issues with aromatization), and brought up AI meds, or other anti-estrogens, but my doctor’s eyes glazed over.

  • aaron

    Dr miller: i am on cycle for 8 months for roids and i just did my pct hcg and tamoxifen and right now i am on clomid today first attempt.

    The question is i seen a doctor the doctor says no need to eat all this etc.. my orignal test will come back naturally, so what is your personal advise ? As you mention the chance of conceive is depends on the sperm count not the level of test right ? Should i just skip the clomid and just let my orginal test to come back ?

    Hope to hear from you soon thanks 😉

  • John

    Dr, l am grateful if practitioners like you are in our part of the world. I will not suffer like this. I pray that my problem is over.

  • mike w

    Dr. – I recently spoke with an endocrinologist about constantly being tired and she tested my testosterone & igf-1 levels. Total T = 765, Free T = 7.6 (LOW) and IGF-1 = 128. Underwent a stim-test of the pituitary and everything was fine as far as the pituitary producing GH normally but the liver is not converting to IGF-1. Was recommended to remove all sugars from diet, then re-test levels in 6 months. Does this sound like advise you would offer to a patient? Are IGF-1 treatments available or must you inject GH and let the body to convert? Which (IGF-1, Free-T) would be more likely the problem with the lack of energy? I have left work in the early afternoons because I become so tired I can’t concentrate, I become irritable, or I’m about to fall asleep. Thank you so much in advance. I’m tired of feeling tired!!!

  • eric T

    Dr. I had a blood draw about 2 months ago my testosterone level was 150. My doc put me on clomid .25 mg everyday, I went back 2 months later to get my T levels tested again after i finished my prescription. My testosterone level was 1600 ng! Which is very good to hear but i don’t feel much difference in anything just have been eating a lot and gained a little weight. What could be the reason i don’t feel the benefits of my high levels? Like benefits such as energy levels, libido, recovery and more focus.

  • Jay Spain

    Dr. I took 1 half cc of enanthate 500mg for 3 weeks. I’ve been on it off and on in the past for 2 years. I am a weight lifter and have only used T no other drugs. I cycled off with hCG 1 mL a day for 10 days injected in my stomach with one pill of Clomid at night for 10 days as well shot in the morning pill at night 10 days this work perfectly for me. Since I got back on the TV it was three months prior to me getting off I cycled off so my next injection three months later after completely cycling off I developed extreme anxiety and I have a lot going on in my life something Trumatic happened I want to cycle off collect correctly is it too early or what should I do since I’ve only been on the test for two weeks. I currently have been almost 10 days now no shot no test completely waiting for her to drop out of my system when should I start therapy post cycle?

  • daniel m

    Dr. Miller I have abused AAS for years and have suppressed my lh/fsh to nil levels. I started hcg/hmg/clomid/nolvadex for the last month and blood came back fsh 3. and lh .02 test 36 free 7 estradiol 25. I have scheduled a semen analysis and am wondering will the elevated fsh create the sperm I desire for impregnating whether through ivf or iui?

  • Jeff

    Dr. Miller – I took 25 mg of Clomid five days on and then five off for about 5 weeks. I got tested and they found my T levels to be at 1100. I am 58 yrs. I am still doing this same routine after 3.5 months. However my libido remains almost non existant. I wonder, why?

  • ScottTee

    Dr. Miller – I was treated four years ago for prostate cancer with proton beam therapy. I had taken testosterone prior to that. Could Clomid possibly be recommended in my case? Can it raise PSA levels? Also, my Rx provider indicated Clomid for me would be an “off-label” use subject to their approval. Your comments much appreciated.

  • michael Fannin

    Dr. Miller I am a 52 year old that had T level below 100. my urologist want to try Clomid before suggesting TRT. Will Clomid help or should I go straight to TRT

  • RSK

    Dr. Miller- I got married in july last year. We tried to do intercourse in jan this year. Initially- it was getting erect but when i try to insert into her-it became weak. We were worried and i visted a urologist. I had low sex drive. Am not feeling to do sex and not aroused even if i do oral sex. took blood test and found testosterone below normal-281.

    He prescribed clomid, ihad for 1.5 months and visited doctor again as there is no improvement but testosterone pumped upto 650.Tested semen level also.1st time: 32million(motility-47). second time: 12 million(motility-33). we are really worried on the results and doctor said am not infertile but you can try by having viagra. It didnt work. He then prescribed Cialis 20 mg.Glad that it worked- we had having clomid till now. We had intercourse for past 3 months and it works only when i have cialis tablet.Is there a permanent cure for this. Clomid is fine, but i have to do it without cialis. Is there a permanent cure and what are the chances i can be a father.

  • low T37

    Dr. Miller I have been on 3 pumps of androgel 1.62 for two years and my T level went to 197 and has stayed there and my doc says that is good enough. After reading this I feel he is wrong, do you know of someone I could see in utah? Dr. Miller: I’m sorry I don’t know any doctors in Utah. Try a urologist with expertise in endocrinology.

  • DL

    Dr. Miller I have taken T shots for several yrs. and testim several yrs. After a recent test my T was 19. Would shots and Clomid help.Thanks

  • Junior

    Dr. Miller I’m on clomid 50mg at the moment but in 2013 my Dr had me on 25mg until our visit in January showed my testosterone levels were low. So he upped me to 50mg and do another blood test in a few weeks. That blood test showed good numbers on estradiol but my testosterone is still low. Due to an auto accident I’m on norco, flexiril, lexapro, lyrica, benicar, clomid and even viagra. My wife and I are trying to conceive but when my body doesn’t work at all, even with viagra, it’s beyond frustrating. Any help is appreciated. Thank you

  • R

    Dr. Miller initally I had migraines during my teens and early adulthood. For that last 18 years I had been migraine free. Started Enanthate at 100mg/week. After starting TRT my migraines returned and my Hemocrit levels increased up to 56%. Reduced dosages to 20mg/week and my migraines have become less frequent and hemocrit levels are back to a better number. But I am now starting to show more signs of fatique and lack of energy. Would Clomid have the same effect on my migraines and hemacrit levels or do think that is something I should consider. thanks. Dr. Miller: I haven’t seen elevation in hematocrit or migraines with clomiphene. The migraines during puberty and with testosterone injectables is likely due to rapid fluctuations in levels which occurs in those situations. Good luck.

  • larry

    Dr. miller my Dr. won’t prescribe clomid is there a Dr. in gigharbor wa that will iam on axiron boncing up and down they want me below 600 felt good at 975

  • SpineFusion_OPIAD_anT

    Dr. Miller

    What are your thoughts on chronic pain patients? I have had 3 spinal surgeries and have a final diagnosis of failed back surgery syndrome. They address this via pain control (not by my choice, but being crippled = not working (desk job)) but my T keeps dropping into the 100’s. I basically suffer from OPIAD.

    My Urologist has me on Axiron, but I keep cycling every 10ish days, and the Testosterone falls, and I become very tired (passing out) and it brings on panic attacks and anxiety.

    I mentioned ‘Clomid’ but she doesn’t seem to think she should do it. I have a first time appt with an Endocrinologist but not for 2 months (busy people) and after a month of this, i can’t ride this (T up/down/up/down roller coaster another 2 months.

    Do you feel Clomid is appropriate here? Are their any risks (ballpark) in prescribing it for 1 month to see if it stops the cycling? The lows of the panic are unbearable and the pain in my spine is more than enough of a load to carry around already.

    My age is 41. My Tyroid has been cleared already, liver function is fine. I just do great eventually for about 4-5 days then the tired, then the panic, then the bottom, and then it has to build up all over again. It’s destroying my life.

    Thanks you for listening, and considering an answer back, I do appreciate it.

    My Uro is unsure and 2 months to see an Endo and i’m in an area where MD choice is limited.

    Thanks You Again

    OPIAD =

  • R

    Dr. Miller

    First, thank you for all you do.

    I was actually assigned to CA operations with my company when it was discovered that I had prostate cancer.

    My current urologist just put me on Clomiphene Citrate.

    I am a 58 year old male. About three years ago, I was feeling extraordinarily sluggish in all habits of my daily routine. I sought the advice of an endrocrinologist who, after a complete blood test, discovered that I was extremely low on testosterone. He started me on Androjel & I began to feel like my old self again.

    When I was relocated to CA, my insurance refused Androgel & I ended up with Testim. Ironically, this drove up my PSA. My doctor recommended a urologist to remove all doubt about cancer. I did have cancer. Fortunately, it was very early on. I had 10 weeks of radiation which did kill the cancer.

    Subsequently, my PSA dropped after a year to a level below 1.0. Dr. started me back on testim. But, my PSA shot up to 3.5, 4.0 & 3.0 successively.

    Anyway, she decided to start me on Clomiphene Citrate for the very reasons you describe. So far, I am feeling more of the drain of testosterone than a revitalization of my testis producing it. I know I need to give it some time.

    My wife consider ourselves holistic & desire a healthy continued life when mother nature drags her feet.

    Your input would be very much appreciated. Thank you for your website.

    Finally, at the heart of the matter, while my current urologist has my best interest at heart, I feel that she lives within the confines of Urology. Your description of purpose appears to be more in line with that of my wife’s & mine. What would you recommend at this point?

    Dr. Miller:

    Sorry for your situation and thank you for all the compliments. Unfortunately, a rising PSA after prostate cancer may mean a recurrence or metastasis and this absolutely needs to be ruled out first. The increase may be cause by clomiphene or testosterone, it doesn’t matter. Please see another urologist about this matter and get a second opinion.

    According to the American Urological Association, Serum PSA should

    decrease and remain at undetectable levels after radical

    prostatectomy. The AUA defines biochemical recurrence as an initial

    PSA value 0.2 ng/mL or greater followed by a subsequent confirmatory

    PSA value 0.2 ng/mL or greater.

    Values obtained with different assay methods or kits cannot be used

    interchangeably. Results cannot be interpreted as absolute evidence

    of the presence or absence of malignant disease.

  • Tom H.

    Dr. Miller, I have normal testosterone levels for my age (67) of 674 ng/dl but my free testosterone is extremely low at 4.8 pg/ml. Would clomid help raise free T levels?

  • Jim

    Dr. Miller, I just completed a six month Androxal Trial. My test levels were below 300 ng/dl to get into the study. The last blood test I had was 895 on the drug. They did 2 more blood test over the next 2 months off the drug and they went down to 495 the 1st month and 415 at the end of the second month. I would like to continue with clomid. I had no adverse health affects from the drug. I am also on drugs for ED, Hypertension, Statin and T2D. I would like to keep my T levels over 800 ng/dl. Could you help me do that? Are you in the Tricare Prime network as a PCM? Dr. Miller: Yes, I can help, however I don’t take insurance. Email me for more info.

  • Chris

    Dr. Miller, what is a typical dosage of Clomid for an average sized 50 year old male? I’ve seen ranges from 50mg to 12.5mg, and from daily to 3x a week. Any insights are appreciated. Thank you.

  • Chris

    Dr. Miller, what is a typical dosage of Clomid for an average sized 50 year old male? I’ve seen ranges from 50mg to 12.5mg, and from daily to 3x a week. Any insights are appreciated. Thank you.

  • Bob O.

    Dr. Miller, any doctors in Northern California (SF Area) which you would recommend?

  • Na

    Dr. Miller, i am 26, when i was 24 i took pro hormones and after taking them i gained muscle but later developed Gynecomastia, they are not too big but are there. My sexual desire decreased, sperm count, and erections became weaker. My dr. Prescribled clomid and they help but a few weeks after stopping i start having bad erections again. Is there a better way to treat this? Dr. Miller: Treatment with clomiphene for a longer period may be necessary. You have to discuss with your doctor.

  • Chris

    Dr. Miller, I am 43, in good health though I have high blood pressure which I take Exforge to control. Since I was a teen I have had gynaecomastia which has always been a source of psychological shame. I had a heart Atrial Fibrilation as an infant, and took an adult dosage of Quinidine and Digitalis until I was 12 yrs old. A doctor told me one of these (don’t recall which), is the likely cause of my gynaecomastia.

    I have read in a few medical reviews (very few having been published) that Clomid has been used for treatment of this condition with mixed results.

    What is your opinion of the use of Clomid for gynaecomastia?

  • Ryan

    Dr. Miller, I am a 26 year old male. I took propecia for 3 years starting when I was only 22. Due to low testosterone, I have been off propecia for nearly 6 months, and seeing an endocrinologist. My testosterone, LH, and FSH levels are low. Estradiol was also not in a good range. Prolactin is high. Doctor has prescribed me Chlomiphene 50mg every other day for 2 months. My question: assuming Chlomid is effective in fixing my levels, should these healthy levels remain after I stop the treatment (will it “kickstart” my system)?

  • Ryan

    Dr. Miller, I am a 26 year old male. I took propecia for 3 years starting when I was only 22. Due to low testosterone, I have been off propecia for nearly 6 months, and seeing an endocrinologist. My testosterone, LH, and FSH levels are low. Estradiol was also not in a good range. Prolactin is high. Doctor has prescribed me Chlomiphene 50mg every other day for 2 months. My question: assuming Chlomid is effective in fixing my levels, should these healthy levels remain after I stop the treatment (will it “kickstart” my system)?

  • Okoho B

    Dr. Miller, I am age 44 .my FSH and LH were both normal but my testosterone is low and I my sperm count is zero . I have low sex drive and am due for TSE in a fertility clinic in two months time. My Dr recommend Fertilovit to enhance sperm production. Can clomid be of help too?

  • Anthony

    Dr. Miller, I am not exactly sure if most of things you have listed in your article above apply to me. With that said, I am having some of these types of problems.. I am a 21 year old male and I have been having serious problems sexually. My libido has seemingly decreased for the past few months and I have noticed that my erections are not as firm as they used to be and I can’t seem to maintain them most of the time. I have been and still am a football player and consistent power lifter. I have taken many different kinds of supplements (test boosters, creatine, fat burners, etc.) but I am not sure if that is the cause of my problems. I did take a cycle of a growth hormone a couple years ago and I know that could definitely cause these kinds of problems in a man; but I went over a year without experiencing any of these sexual problems until now. I am very confused with this and quite frankly, this is really devastating for me. I am at such a young age and i should be flourishing in this department but for the past few months I have not been able to perform like I have in the past. If you could please help me in any way, email me, or anything that can help solve my problem, I would greatly appreciate it.. Thank you

  • A

    Dr. Miller, I have been on clomid 25mg every other day for 5 weeks as prescribed by my Endo. My test levels before clomid were 250 and now the levels have only risen to 265. After reading so many positive reviews about clomid I was very disappointed that my levels did not rise higher. Have you seen cases where clomid does not work for some people? Should I speak to my dr about raising the dose to 25 every day? Is there any difference in effect of clomid at 25mg ED or 50mg EOD? Thank you!

  • Nate

    Dr. Miller, I was diagnosed with low t about 8 months ago and have been prescribed (urologist) cypionate 2ml every 2 weeks (400mg). I feel decent for about a week and then I decline after that until about 3 days after next shot. I’m retaining a good amount of water…enough that my knees hurt quite a bit. I went to another doctor to check on other options. He seems to want to actually see if we can fix the problem which would be great. He started me on Clomid 25mg but since I started (shortly after my shot) my blood pressure has skyrocketed. From 120-140/75-85 to 180/100-116. Could this be related to the clomid? I have stopped test shots. My libido has me feeling like I’m 26 again (I’m 37). It is strong. I’ve felt pretty good except for the blood pressure. I don’t have a lot of confidence in this doctor aside from his progressive approach with clomid. Dr. Miller: One would need to have blood work to determine if any other problem could be causing high blood pressure. Any side-effect with any medication is possible though.

  • Al

    Dr. Miller, I was diagnosed with non obstructive azoospermia. Due to my low T, my urologist suggested taking clomid for 3 weeks. After that they were able to find few sperms during analysis.I moved to a different location now, my question is if I keep taking clomid for a longer time like 3-4 months, will the sperm count increase? Also how long can I take Clomid? Thank you!

  • BB

    Dr. Miller, I’m a 48 yr old male. Muscular but also carrying at least 40 extra pounds. I lost 30 recently (started at 70 lbs overweight) while on clomid for six months, exercising and eating very healthy. Diagnosed with secondary hypogonadism prior to starting clomid 25 mg EOD. Total test went from 250 to 550. Feel much better. However very worried about dangers of taking clomid for more than six months. I seem to have significant increase in eye floaters so worried this is caused by clomid and staying on it will make this side effect worse. What is your experience with clomid and eye floaters? How long is safe to take clomid? Is switching from clomid to HCG at this stage something that could be effective? I don’t want to lose the benefits of clomid but also don’t want to permanently damage my eyes. Thank you in advance for any info you can share. Dr. Miller: Yes, any eye disturbances can be caused by clomiphene. HCG is good alternative when clomiphene causes side-effects.

  • John

    Dr. Miller, is it still possible to contact you through this page?

  • Mike

    Dr. Miller, thank you for all this information. What do patients typically see for their FSH levels after being on Clomid for 3 months. I had no sperm, T 119 and FSH 79. I started clomid and each month my T drops (78 now 50) but my fsh drops (50 now 30). I thought clomid would cause FSH to either remain the same or increase. I only have one testicle due to trauma and the other one is slightly smaller now than 15 years ago. If T keeps dropping on Clomid is that a sign the drug isnt doing anything?

  • Kevin

    Dr. Miller, what is your experience with men coming off of Clomid cold turkey? I’m asking because I was on 25mg per day, first few days I had MAJOR MAN PMS (anxiety, irritability…etc.) that went away and then I got very light headed a lot of the time, went down to 12.5mg per day still light headed, but didn’t feel the benefit anymore either.. went back up to 25mg /day and just endured the daily light headedness. Did that for 6 weeks and finally gave up and since I was on such a small dose and since it has a 5 day half life, I decided to just stop cold turkey. I noticed I got the worst MAN PMS yet (major anxiety, irritability…etc.) It’s only been a day and it’s getting better for sure… But I was thinking maybe it’s because my estrogen receptors up-regulated due to the Clomiphene taking up those sites everywhere in the body…then stopping, my body is making it’s own Testosterone again and also converting it to estrogens (estradiol) and with significantly more estrogen receptors, maybe it’s just as if I had a boat load of estrogen dumped in my body…which is probably what happened when I first started? Does that sound like a plausible theory?

  • Lance

    Dr. Miller,

    Have you ever treated a patient using clomid and testosterone injections simultaneously?

    Hypothetically, is this something that would be counterproductive if fertility was a concern?

  • Andy

    Dr. Miller,

    I’m 35 with T of 550, found after infertility work-up revealing low sperm count, poor motility, and fragmented sperm DNA – all of these were below normal, but none drastically abnormal. The DNA fragmentation prompted a more careful testicular exam, which revealed bilateral moderate varicoceles – which could explain the fragmentation (heat causes more free radical). Through the same presumed mechanism Varicoceles are known to also lower testosterone production/levels. Varicocele surgery has been offered, but I’ve held off. Furthermore, I’ve noticed my energy, motivation, libido, and erectile function wane significantly over the past 5-6 years. I know that by the numbers i don’t have hypogonadism, and even if i did, at least a component of it would be primary, but do you think clomiphene could help me? If so, do you know any practicioners that you would recommend in Atlanta?Thank you kindly

  • Carroll Roberson

    Dr. Miller,

    I am taking Clomiphene, and it really is working. Just wondering if they are any long term risks? I take one 50mg every other day. Is there a natural alternative to Clomiphene? Thank you

  • Jeff

    Dr. Miller. I am a healtjy 45 and have been on clomid for 9 months. This is the only mesication I take. I take 25mg daily since 3 months ago after initially taking 25mg every other day. Recent testosterone 699 with normal FSH,LH and CBC. I just found out I have a blood clot. Could excessive estrogen contributed to the blood clot? Not sure if estrogen level obtained. Have you heard of clomid causing a blood clot?

  • Tyler

    Dr. Miller: Wow this was an extremely interesting article. I have been having Low T symptoms as of late (22 years old) and recently got checked out. My total T was 455. I have absolutely no libido, ED, and just don’t feel good overall. Was wondering if 22 year olds could take clomid without any adverse side effects to possibly get me feeling back to normal? These symptoms have been going on for around 6 months. Thank you so much.

  • Similarion

    Dr. Miller: After noticing decreased libido and weaker erection over last couple of years ( i am 35) i went to Dr who prescribe me ciais, which sometimes worked well. My T he sai was in low normal range but he sai it was low considering my age. He said he did not want to start me on Ex tes due to my desire to have children and he recommended getting over stress etc.

    I once took a tablet called proviron with the active ingridient of Mesterolone. Looking back, (the drug worked wonders for sex the next day) my problems only started after taking this one tablet…could this have caused a decline in my TE and libido?? I asked my DR bout Clomid, however he mentioned that it would be effective for one month but thereafter Clomid stops working for me…Is this true?

  • Matt H.

    Dr. Miller: I am a 42 year old patient and have been on TRT since mid-2007 (cypionate injectable at .45 ml p/week). At the time I was diagnosed with idiopathic secondary hypogonadism. During this time I have moved twice and was told about Clomid for men by a former PCP. My current endocrinologist indicated that the use of Clomid is only effective for men who have not been on TRT before. Do you have any research sources to indicate otherwise? Also, I noticed above the request for a doctor in Utah. The doctor that originally diagnosed me is Dr. Kaldhoun Al Rayess (Endocrinologist) at the Tanner Clinic in Layton, UT.

  • William Miller

    Dr. Miller: I have suffered for years from what I was told was depression and placed on antidepressant after antidepressant. Then a routine physical I asked for a total-testosterone test and it came back 281, then 341. Was placed on Clomid 50mg 3x weekly and felt better but doctor was not comfortable prescribing long-term even though my level fell to 254 a couple of months after stopping Clomid, and he sent me to an endocrinologist, who found my level to be 480 and said I was fine. Meanwhile a clinical trial for a testosterone gel here sounded promising, I went in the same week I saw the endocrinologist and tested at 292. But the trial quickly filled and I did not get in. So now my regular doctor who diagnosed low T originally won’t prescribe Clomid or testosterone because the endocrinologist said 480 was fine, even though that same week, the clinical trial found 292. This process has dragged on now for nine months and I am beyond frustrated. Do you know of a doctor in Orlando who is more receptive to treatment? Thanks in advance!

  • dds

    Dr. Miller:

    What are your thoughts about taking Clomid and Chrysin 500 (as an AI) together? Does Chrysin really work as an AI or is this primarily a myth and not based on actual factual evidence or research?

  • Pancho

    Dr. Miller; Is Clomid a possible treatment for men over 75 with lower libido, low energy and slight diet resistant belly fat?

  • Jason L

    Dr. Miller–Would Clomid help if someone has normal ranges for LH and FSH, but with a low testosterone serum of 168? Or would this be useless since he’s already producing LH and FSH? Thanks!

  • Billy


    Thank you for providing this information, it has really helped me get a grasp on things. Generally speaking, how long can a man be on clomid? Can it be indefinitely? I wasn’t sure if this could be a replacement altogether for other low T treatments (gels, injections, etc), or if this was only a “short term” option (assuming the clomid worked)?

    Thank you for your help!!!

  • SK

    Dr.Miller, I have read somewhere that Clomiphene Citrate has a side effect of causing Change in sex drive in men; is this change referring to increase or decrease of sex drive.

  • K


    Thank you for the informative article on low testostrtone .I have secondary hypogonadism for past two years, low fsh,lh and testosterone. I went to hospital because of growth in breast size.Other than this I had no other complaints, have good energy levels, no headaches, no problem in achieving erection. In addition to test the Dr checked function of liver, kidneys, pituitary by checking hormones produced by it. All test came out normal. My Dr put me on 50mg Clomiphene twice daily for two weeks in a month and anastrozole 3 times a week for four months. I was to continue with this treatment plan for four months. I have been taking Clomiphene for three months and decided to check my testosterone levels. It saddens me to tell you that there has been no improvement in my testosterone. Generally,is clomiphene really for me and what may cause it not to work to improve my testosterone levels. We don’t have good medical care from where I come from and I would appreciate if you may suggest what other additional test I should do to get over this challenge. Dr. Miller: I’m sorry you haven’t been helped. I can’t give personal medical advice here. You need thorough evaluation for cause. Are you on any medications, for example? Clomiphene is also usually dosed daily or every other day, not only two weeks of month.

  • sam

    dude low t is not called hypogonadism its called androgen deficiency, google images hypogonadism.

  • Mike

    Everyone should be very aware of a drug like clomid being off label. There are risks that neither this article not my urologist ever mentioned to me. I used clomid for about 5 months and it worked amazingly. T Levels went from 300 to 600+ and I had more energy, etc… The downside is it also accelerated my hair loss cycle as shifts in hormones quickly can do. I’m now balding in several areas. Urologist just cites that this “can happen” when increasing T levels as DHT is blocked faster. I am at a loss what to do now as I am off the clomid, still haven’t grown back the hair (going to start Kirkland minoxodil for this), and have T levels back in the 250-300 range which for a 40 yr old guy is unacceptable.

  • Steve H

    First off, your website has provided me with invaluable information, so thank you! My question: I’m a completely healthy 30 year old male who takes methadone (for chronic intractable pain) which has caused my testosterone levels to drop to 76! Yes, that’s right 76. I have been on Clomid 50mg every other day and 60 mgs (2 pumps) of axiron every day for two weeks now…… test levels went from 76 to 189 in two weeks. Is there a chance that taking Axiron combined with Clomid can actually cancel each other out? I know you said that they both do opposite things? So will taking clomid along with axiron or any other test replacement further increase testosterone levels or should be they be taken at separate times? I was hoping that my testosterone would have increased by more than just 100 from two weeks of clomid/axiron……buttttt it didn’t! Thank you very much.

  • Ray V

    For the person who has venous leakage

    penile injection therapy will help or probably solve the problem. Just Google it.

    Also, what is the suggested daily dose of Clomid?


  • fadel

    fsh 6 miu\ml 1.6\ 11 lh 5.71 0.8 \ 9.1 prl 5.98 ng\ml 2.7 \16.9 testosterone 3.36 ng\ml 2.6 \10.1; sperm 3 million after 2 month with 25mg clomid daily and hcg 1500 3x weekly last day of 2 month i make hormone test i find testosterone go up 7 and fsh go down 0.8 i wait 1 month and make sperm test i find 1.5 million go down what i will make now. Dr. Miller: Thank you for sharing.

  • TONY

    FSH IS 1.8 AND LH IS 2.7 AND TT IS 384 WITH SHBG OF 12. IS CLOMID GOING TO HELP WITH THAT. Dr. Miller: That is consistent with secondary hypogonadism, so clomiphene could help. But, you need to figure out what is cause of secondary hypogonadism, additional testing should be performed.

  • Mark Smith

    FYI. I stated clomid 3 months ago. Last blood test showed testerone up to 480.

    Testicals were srunk to almost nothing after two years of testosterone gells that did not work for me.

    I am a prostate cancer survivor and had my prostate remove 13 years ago..

  • Harry

    Good morning dr. . I just had my hormonal profiling done as my wife and I are trying to conceive at the moment. My dr just put me on clomid today. He asked me to use it for 5 days and go for anther test.

    Though I feel from reading post by other reasons that I know where the low T levels are coming from as for a couple of months I have been feeling very depressed especially in my job.(banking). Also I found myself interested in eating only once a day I have kept up this eating habit for over 6 months I have lost a little weight also.

    my question is do you think 5days is enough for me to take clomid. And I have noticed some other reader say they have used clomid for 6 months. Note the warning in the package is that clomid should not be used as a monthly treatment.

    I would appreciate better education on how to use clomid especially for men.

    Thank you

  • Chris S.

    Great article/read, thanks for the info. 30 yr. old who got prescribed androgel for 3 months to see if it would help my low T. I have my doubts it did anything and also read somewhere it may actually harm my sperm production. May try for a third kid in the next few months so hopefully it didn’t do much harm. Anyway, going to ask to get referred to a urologist as I believe they might be able to give me some better answers. I’ll definitely ask about clomid, also about hcg. Really dislike the gel!!!!

  • Jeff

    Great information here thanks for doing this blog! I’m 45 year old male with T levels that hover around +/- 150 (without treatment). For about a year I was on various doses of Androgel. It did not raise my T levels at all. Next was Testopel injections that got my levels to 450 at a high point. Now I’m on Axiron which seems to be working not sure what my T levels are yet. One thing I have noticed with all of these is sleeping issues (insomnia, waking up, etc…). I have sleep apnea and use CPAP. Do Clomid and/or HCG have similar side effects? Dr. Miller: Sleep apnea is a known testosterone treatment side-effect. I haven’t seen clomiphene or HCG causing sleep apnea, but suppose it is possible. Real question is whether you have primary or secondary hypogonadism, and whether primary problem is being treated.

  • JimE

    Great information here! I have been injecting Testosterone for several years and am very low naturally. Doctor is always adjusting doses which seems to crash my levels most of the time. Last blood showed 1100! It was a little high but still in normal range and explained I felt good at those levels. I also explained I injected the night before blood work as well as only 5 days since my last injection, instead of 7 days. This seem to keep my levels more stable. Doctor cut my dosage from 1ml a week to .5ml. Problem is its way to low and levels were always bellow 300 and crashes even lower at the .5ml dose she recommended before.

    I also complained about lack of erections and difficulty to finish sex. This is the major reason I persued HTR in the first place, due to declining sexual drive and performance as well as low energy. Wanted to please my wife. Testicular

    atrophy was also apparent. I asked Dr. for help,

    but she wouldn’t give me any other medications to

    help combat the negatives sides. The doctor is my primary. Should I see a certain specialist to help with this such as a Eurologist? Are there any recommendations for specialist in south Florida?


  • M

    Have been stressed out by life but test levels came back at 188. I had an undescendent testicle as a kid and had it operated on. It has always been much smaller than the other one. My sex drive through my 20’s-30’s was always good and am wondering if only having one fully functioning testicle means I only have some of the test I should. My test readings from 2009 were 355 and urologist said all was normal even though for my age at the time should have been 800 or more. Am 43 now and have soft weak erections that happen and then go limp. My muscles ache too and energy sucks. Can Clomid help? Any Dr. In the Washington DC or Northern Virginia area that can help? Dr. Miller: LH and FSH need to be checked to give best indication of whether or not clomiphene will help. Contact Dr. Warren Levin in your area.

  • Ahmed

    hello – I was diagnosed with low testosterone 240 first test / 310 second test and doctor put me on a course of clomid for 1 year. This increased testosterone to 730 and I felt benefit. I’ve now stopped clomid and test has dropped back down to 290 last test. Is TRT now only option? Have you heard of androxal doctor? What are your thoughts on this? Thank you. Dr. Miller: Clomiphene can be used long-term. Androxal is a single isomer of clomiphene but is likely much more expensive.

  • Drew

    Hello doc,

    It seems like clomid could help but I’m not sure.

    I am 30 yrs old and was diagnosed with hypogonadotropic hypogonadism when I was 17 die to not hitting puberty. Ever since I’ve been on testosterone shots.

    MRI scans show no abnormalities.

    Do I need to stop taking test before clomid? Because I’m on reandron which elevates test for 4 months.

    Or can I take clomid with reandron and then get blood work to check if fsh and lh have increased?

    After reading this I’m also worried about eye floaters, are the reversible?

    Thanks for any help.

  • Sanya Ghoshal

    Hello Doc,

    My husband has a very high level of Estradiol (E2) (= 438.00 pg/mL) but his testosterone (= 381.91 ng/dL), LH (= 4.32 mIU/mL) and FSH (= 2.44 mIU/mL) levels are normal. He is diagnosed with oligospermia with sperm count equal to 7 million/ml. He also has some issues of DNA fragmentation and morphology. Though his progressive motility is around 60%. I read that high E2 levels in men can lead to sperm issues and infertility. How can we correct this abnormal E2 to testosterone ratio successfully? He was put on Clomiphene Citrate (50 mg/day) for 16 weeks between June and September.


  • John

    Hello Doctor — thanks for this website.

    What are your thoughts on Clomid possibly helping to increase normal sperm morphology percentages?

  • DJS

    hello doctor me and my partner have been trying for a child for many years but no 44 andi have a low sperm count,my fertility clinic has told me to take clomid for 3 months 25mg aday to try and increase my sperm count, is this dosage enough and is 3 months enough,i really would like a child naturally not ivf,,,many thanks

  • salah

    Hello doctor

    Thank you for the invaluable information.

    I have 1 question:

    I’m a 27 years old man, married for over a year, wife is 4 months pregnant, I have long history of obesity since childhood, currently I weight about 110kg, but no other health/sex life issues.

    About 2 years ago, I discovered a herb extract used as aphrodiastic that is supposed to boost endogen testostorone level. After intermittent use, I felt the change: better self confidence, deeper voice, less social anxiety, more developed muscle, androgenic-like obesity, better mood and well being, less mood fluctuations

    Thinking of testosterone as a cause, it all made sense.

    The problem is clomid is much more accessible to me, and if it can get my testosterone level higher, is there any reason why i shouldnt use it on the long term ?

    Im very interested by this substance, but utterly afraid of its effect, mainly higher oestrogen levels.

    Thanks. Dr. Miller: I cannot give personal medical advice here. You need to find a doctor who can do blood testing and a consultation. Good luck!

  • Ryan

    Hello Doctor, I am 28 and have fibromyalgia. I was taking androgel for about 1 year, along with hydrocodone, morphine hcl, lyrica, limbrel, chlorozoxone, and levothyroid (for hypothyroidism). I had never received any warnings from my urologist about the possible negatives of taking a testosterone replacement and find it recently online. I weaned myself off of it as I started taking vitamins with L-arginine in it. I will be asking my doctor about Clomid and HCG when I see him next month thanks to reading this. I had noticed that since I started taking the androgel I eventually felt like my sex drive actually decreased, and my testes had shrank some. My urologist has been rather judgmental of me for taking Rx pain killers. Which unfortunately I really cannot go without due to my fibro pain being as painfully strong as is. I had went through all types of medications for fibro and lyrica was the only one I could take that worked or had the least side effects from. Unfortunately though, I cannot take the dose my Dr recommends or I risk impotence side effects. I am hoping though, that if I do begin taking Clomid and or HCG that I can increase my lyrica dosage and with any luck not have the side effects and get myself off the pain killers. I am wondering if you have any knowledge of any patients similar to myself around my age with fibromyalgia and hypothyroidism? It has been extremely difficult for me since my fibro suddenly started approximately Oct 2011. Thank you. Dr. Miller: Opiates can cause secondary hypogonadism. You need to find an integrative doctor that can help determine the cause of your fibromyalgia and reverse it.

  • Aditya

    Hello Dr Millee…. Really need your help & advice….

    I’m 45, 77 Kgs, mild hypertension (use basic Med). I work out 4-5 times a week.

    I’ve been facing ED issues. My blood work results are as follows… Total Test – 598; Free Test – 6.6; Estradiol – 36.6.

    Are these figures ok. I think free test is low & E2 is high.

    Do you think Clomid would help…or any other suggestions? I don’t want to start steroids or trt. But I certainly want to get my libido back.

    Really hope you can help. Many thanks.

  • Rahul rai

    Hello Dr Miller thanks for article, am 29yrs, my T levels are low, I was using androgel initially but it’s not so effective now, then I switched to testosterone undecanoate 1000mg IM injection on first injection for one week my mood was good, energetic, verbal influence is increased, but after one week effect started decreasing, like am feeling started depressed, why is it so? Even with testosterone enanthate effect will stay up to one day only, how to deal this clomid will help?? Please help

  • roami

    Hello Dr Miller

    my story is long but i will try to make it short.when i was 20 years old i had a sex with one woman at nite and after sleeping overnite when i got up my testeees and penis was swollen like baloon and i was having gr8 pain and high fever then i went to doctor he freezed my testees and he sucked blood out of my testees and with in one hour my pain was gone but after few days i felt my testees were shrinking and finally both disappear when i went for sperm test it came zero in fact i was not having any liquid comning out i mean i was not able to cum and if cum it was just one or 2 drops of water only -currentlly i m on t injection from last 10 yrs but still my t is abt 200 and my erection is so weak .

    Hounerable DR.DO u think clomid will help me for good erection.

    i really appriciatte ur early answer


  • Sidney

    Hello Dr Miller, I’m taking Clomid and my estradiol levels are very high but my doctor doesnt want to prescribe me anastrozole. Do you know any doctos in Canada that is familiar with Clomid and anastrozole in men? I live in Vancouver/BC. Thanks!

  • Joseph

    Hello Dr Miller, would clomid help for hypogonadism ( testicular atrophy ) due to chronic opiate use or does HCG necessarily have to be included? Thank you in advance

  • jayjay

    Hello dr. I was wondering im a diabetic in my 30s and take thyroid ,metformin, glipizide, and a cholesterol medicine. i just got told i have low t levels and was prescribed this clomid but was really concerned about side affects from my others meds. is there a safety risk??? Thanks. Dr. Miller: There are potential risks with any medications. Find a doctor who can help you reverse your diabetes and thyroid as that may resolve your low T.

  • Larry C.

    Hello Dr. Miller, does Clomid/Clomophene have an affect on hematocrit?

  • Brian J.

    Hello Dr. Miller, I have secondary hypgonadism probably caused by having to take pain killers for a few years. I had spinal surgery a little over a year ago and have been off opiates/opioids for pain since. We are trying to get pregnant with our second child with no success yet. My sperm count, morphology and motility were bad on the pain meds, but have been slowly increasing since stopping pain killers. Semen analysis is now normal in all areas but my motility was 43 percent and normal is 50. My current testosterone is 237. My Urologist did all the necessary tests and ruled out all other conditions regarding low testosterone(he feels it is probably secondary hypogonadism caused by opiate use) and feels I need a kick start so he put me on clomid 25 mgs a day. I have been on it 5 days and notice I have more energy, I am able to excercise and I am no longer depressed! —-My question is, with my weight and height, 5’11” 190 lbs, will my size cause more estrogen from the clomid because of the extra fat on me? Not in general, but with respect to my specific height and weight. I am probably 10 to 15 pounds above ideal weight. I do not look fat but I do have some spots here and there.—Thanks so much, your blog is incredible!!!

  • BD

    Hello Dr. Miller, I’m very pleased to have found this forum albeit over a year after the fact….There are so many questions and you’ve probably answered this before: But can Clomid be used to help with fat loss, especially when a bit of insulin resistance is probably at play?

    I’m 34 years old, I have over 30% bodyfat…but I don’t quite “look” as much as 30% because I have some muscle mass from lifting weights. (Definitely noticeable “belly” though, and definite “feminine” fat-distribution in the hips). I know it affects my estrogen level -as exemplified by the large amount of “feminine” fat- and apparently my insulin resistance too (the belly and waist). And I have had sexual side-effects at times e.g. weaker erections…So I need to lose the fat for obvious reasons.

    I also understand that the high bodyfat -and therefore high aromatization- could potentially “negate” any testosterone increase from say clomid (I think this has happened when I use “natural testosterone booster” herbal supplements). At the same time I have such a hard time losing the fat that I wonder whether the high estrogen isn’t itself making this difficult, and therefore need something to counter-act that estrogen?

    So can clomid itself be used as an adjunct -maybe even a significant part- in helping to lose significant bodyfat? Given that losing the bodyfat would of course be the ultimate “real” solution….

    Thanks much.


  • Dr. Moore

    Hello dr. Miller, my patient is suffering of low libido, erectile disfunction, lack of motivation and performance. His total T is normal, SHBG elevated and free T lower than normal, also his DHT is below norm. His FSH and LH are fine therefore it looks more like primary hypogonadism and/or insufficient 5alpha reductase. Would you still advise to try Clomid in this case?

  • Mike

    Hello Dr. Miller,

    I am 39, had high FSH and low total T with zero sperm count and relatively smaller than average testicles. Genetic tests all showed normal results.

    I have been on Clomid for 3 months. My sperm count is still zero but T went from 4.74 to 13.1 nmol/L. and libido has even increased.

    Is there any method to confirm the existance of at least one sperm other than having to do a micro-TESE? any scan, ultrasound, MRI, etc…?

    I am willing to go under the knife and try anything to extract sperm just if I know my body is making some and I am not completely sterile.

    Please help and advise.

    Thank you.

  • RR

    Hello Dr. Miller,

    I was prescribed 50mg of clomid, 2 times a day for 15 days. (100mg per day)This was post therapy treatment after a 20 week course of testosterone injections. Shortly after beginning the clomid I developed a genital rash that became progressively worse. On day 14 of the clomid course, I quit taking it. The rash began to clear up immediately, though it has been a day to day progression for the better. Is it possible this was an allergic reaction? 62 yo male.

  • Dan in Denver

    Hello Dr. Miller. I turned 48 a few months ago it seemed like a switch went off inside my body. I now don’t get good sleep and often wake up with extreme night sweats. I also seem to run out of gas in the early evening. Sexually, while I’ve always been severely ashamed of my premature ejaculation condition, but now to make matters worse my once insatiable sex drive has screeched to an abrupt halt because of my new inability to maintain an erection. My wife is baffled because up until 2-3 months ago I was still chasing her around the house at night and waking her up in the morning with no problems, except for the PE. I went to a urologist but they just wrote me a script for Cialis and sent me on my way. Then I researched Testosterone therapy and went to ask my family doctor about it. He tested my levels and my T came back 249 so after some persuasion he started me on Aveed. I drove home with the hopes of turning into a porn star over the weekend, but to my surprise alter 7 days of my first injection I couldn’t even get an erection, much less maintain one. Ugh. Because I’m a relatively healthy guy under 50 who loves his hot wife, I really don’t want to have to keep a bottle of expensive pills hidden in my night stand for the next 20 years. My question: do you think I should continue on Aveed for a while before I plead my Clomid case to the family doctor? The problem is that I really like sex so even 3-4 days without it is a shocker to the wife and I. Or, should I discontinue the Aveed and open up the yellow page to find someone who will put me on Clomid? Thank you!!

  • BB

    Hello Dr. Miller. I have read in your answers to posts that vision disturbances are a known side effect of Clomid. However, you have also written that vision disturbances are rare. My question is based on your experience in your practice, have you ever seen a patient on Clomid develop eye floaters? And if yes, then how prevalent is this particular vision disturbance in your experience (i.e. one percent of patients, one tenth of one percent, five percent, etc)? And lastly, have you ever seen eye floaters develop on a dose not greater than 25mg EOD for six months? Thank you in advance for your answers.

  • Wholbrook

    Hello Dr. Thank you for answering everybody’s question. I am 45 yrs old and have an empty sella. I have been on and off T injections for the past 3 yrs. I was around 250 t level prior. I’m not sure if Clomid can help someone with an empty sella, do you know if it’s possible and is Clomid only for younger makes?

  • eric

    Hello every one I want to stand tall as a man and truly appreciate what some one has done for me my name is Eric, and am from Scotland I came across a post of Dr Alaska and how he has been curing people of various diseases I did not believe at first so I decided to contact he to know if there is any cure for my 4 years weak erection.when I contacted him I narrated my problem to him and he advice me on what to do he said do not worry that all was going to be well. i receive his medicine and after taking it I went for a test and I discover that I was now okay I can now do what I was not able to do before am so grateful for his cure and help I also introduce him to my uncle`s wife she was experiencing total weakness of the body and she was also having problem with her virginal and when she contacted him all of these diseases became stories and they are living as a united family now.all thanks to Dr Alaska for all his help. you too can be cure of that disease you think has no solution just contact him at or call him on +2348169591194. is cost free

  • vera morgan

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    for all your spiritual and family issues

  • johnson philip

    Hello everyone, i had a poor erection from birth, i noticed myself when i was 7years old. my penis is very small that its only use is to pass out urine. when i was 23, i tried to come close to women, my penis will not stand erect to make love. this has been my greatest problem until i met a man called Dr.fara. he assured to cast a spell on me for long penis and erection and high sperm count. it seems like a dream to me, i decided to give it a trial because this has been my greatest problem and medical attention have not been of help. it seems shock to me. i made love with the girl i have always dream to be with and i intend to get her pregnant. i know its not easy to live in this condition so i cannot keep this miracle to myself. i urge everyone in similar condition to contact Dr. fara today via email Any problem you are, he has a way of bringing solution to it. if mine is possible, then i can say nothing is impossible. contact him today via email there will be a miracle, and you will share testimony as i am doing now. feeling happy!!! grateful heart!!

  • Bruce D.

    Hello I am 46 have low T with my levels being around 212. Recently I was tested and my T level was 229 LH 1.2 FSH 3.8 Prolactin 8.2 and free T was 8.2. I am seeing a Endocrinologist and am not sure what to expect. I have injected 400mg/week of cyp along with HCG, anastrozole and felt like a kid again. I am thinking my issue is secondary, should I bring up Clomid to my doctor?

  • Wafneur


    I’m 33 and have been on and off TRT for the past 7 years. I am 6 ft talla nd weigh 215 lb. My total T level is usually 6-8 nmol/ L out of a range between 7-25. Some doctors have diagnosed hypogonadism while others have denied it. My sex drive was normal before initiating any form of TRT , but sharply declined during and after it. On Androgel I experienced loss of libido and near constant breastfeeding tenderness and slight growth. I the meanwhile I discovered I had sleep apnea, which sharply reduced last year thanks to a mandibular appliance. However 3 months of normal sleep did not raise my T levels. The endo put me on 160 mg of Andriol a day. It had some positive side effects, mainly on energy and drive to act, but my libido was low and I experienced tiredness and indigestion on it. I stopped and have been prescribed clomid 50 mg/day in an attempt to restart the pituitary, considering that sleep apnea has been successfully treated. On this dosage of clomid I started feeling after 3 weeks intense pain in the breasts, especially the right side. Sex drive remains low but slightly higher and more consistent than on TRT.


    – What can be an underlying cause of my LowT? My responses to TRT have been very paradoxical. Lh is low normal or low, fsh is low, Total T ils low Normal or low. Shbg is low normal. Bioavailable T is midrange. Sister has same energy, motivation low levels and becomes easily over weight, as me. She has a cushingoid appearance and body type

  • Bryan F


    Dr I have a few questions I would like your opinion on. Could I email you and if so how do I go about getting your email address?

  • Markus

    Hello. Just got back from my primary care doc. Was previously on TRT 100 mg per week of test cypionate. While on the TRT I experimented with Semoralin to help improve my GH secretion for anti aging. I’m 34 years old and now having all symptoms of low T. I have been off TRT for 4 months and off semoralin also.

  • Julianne C

    Hello. My husband and I have been ona roller coaster. He has an extremely high fsh and lh, small testicles, and now his T level is going lower. He’s been do a urologist, endocrinologist, and infertility specialists because we want to get pregnant. We were told he will never produce sperm because he is azoospermia. He started on T shots and I am concerned bc it can make him more sterile. Can he take clomid with a high fsh and lh without causing more damage instead of T shots?

    • Usually if the FSH is high, then the diagnosis is primary hypogonadism and clomiphene doesn’t work in that situation.

  • Mary

    Hello. My partner has a low testosterone level however has always has barely any hair on his eyebrows and spots missing on his legs. I perceived an androgen issue?

    Anyhow after seeing a muscular geneticist as he seems to have some cognitive impairment and muscle wasting according to them the bloodwork found no common neuro muscular disease. He has high cholesterol, high blood pressure and sugar issues although not tested + for diabetes. Libido is a huge issue as well as speech/thought. He went on testosterone pills for a few months and he really boosted his energy levels however it did not help with the muscle issues. He has excessive thirst and a high metabolism and very pale. We are considering metformin for the hyperinsulin state he is in however the clomid may be better. We have seen doctors worldwide without much diagnosis. His creatine protease level was 300 which to them was an indicator something was up. Help! Will clomid and metformin be ok to increase his insulin sensitivity? He is 36 and looks very young. Dr. Miller: Please schedule a phone call to discuss.

  • Dan

    Hey doc!

    I have most of the symptoms of low T (lethargic, weak erections, lack of sex drive, slight depression, gain fat easily, and no muscle gain despite years of proper training and diet.)

    I’ve been to several doctors and my T comes back at around 400 every time. They say I’m just depressed and put me on wellbutrin.

    I’d like to find a doctor that can treat my symptoms instead of seeing me as just a number. Any advice?

  • vusimuzi

    Hey doc, I’m from south africa and my wife took ferti-plus and had a spontaneous abortion, the I bought her clomid and she had an actopic pregnancy! I’m asking doctor, is it me who has a problem or what? I’m afraid of putting her back on clomi and I think it will be best if I drink it myself, thought I don’t knw if I have a problem myself. Please advice what must I do?

  • Mark

    Hey doc.. I’m 20 years old my total test level was 404.. And then 98.. I feel terrible and I don’t know what to do.. I look healthy muscular have facial hair and body hair.. Is that even possible with such levels ? Im seeing another doctor and confused on what hormone tests I should ask to get done to figure out my problem? Thank you

  • Matt UK

    Hey Doctor,

    What a fantastic and enlightening site. I’m an active, sporty and healthy 32 year old man and live in the UK. I went to see my GP about 9 months ago suffering from a complete loss of interest in sex, a general constant feeling of lethargy/”mind fog” and on and off mild depression. He suggested a blood test and my test levels came back at 280 which he said were “within the NHS range” and therefore to be considered completely normal. I did some research myself only to find that test levels of 280 in a 32 year old man were anything but normal and everything that I was experiencing could be attributed to low test. I requested another appointment with my GP and forced the issue until he agreed that I should see an endocrinologist. I paid to go private as waiting to see an endo on the NHS can take months in the UK. The endo suggested that another, wider test should be taken – the results below…

    Follicle Stimulating Hormone – 1.8 IU/L (1.5-12.4)

    Luteinising Hormone – 3.5 IU/L ((1.7-8.6)

    Prolactin 282 mIU/L (86-324)

    Sex hormone binding globulin 24 nmol/l (16-55)

    Test 10 nmol/l (9.9-27.8)

    Thyroid stimulating hormone 0.95 mIU/L (0.27-4.2)

    Free Thyroxine 16.6 pmol/l (12-22)

    Total T3 1.9 nmol/L (1.3-3.1)

    As you can see – my “test” is very low again (just within “the range”) as is my FSH (just within the range). The endo took one look at the results and told me that I was “within the range” for everything – that I needed to see a sex therapist!?!?!?!? To be honest, this was an insult. I again did my research and I’m going to try to resolve the issue myself through very low dose clomid 25mg M-W-F for 6 months and then try and slowly come off. Throughout I’ll be taking blood tests to evaluate if it is working. I took a blood test this morning as I start the course of clomid tonight. Any advice or recommendations appreciated. Wish me luck. Kind regards. Dr. Miller: I am so sorry you are having trouble finding good medical care. Maybe try to find a urologist in the UK who knows about clomiphene. Or you can come see me. 🙂

  • david

    Hey dr, took test last year and have had low t for about a year now. 2 miscarriages, and low lobilo as well. Thinking of trying clomid?

  • LifeWithLowT

    Hey Dr. Miller,

    Glad I stumbled across your website. I am 34, been dealing with LowT since i was approx 28. For those on here complaining about Propecia, I believe this to be the culprit in my issues and advise you all Google “Post Finasteride Syndrome”…it has been shown to cause long lasting and even permanent issues. That said, I have tried everything: Androgel, Testim, Clomid, Arimidex, HCG, etc…clomid has shown me the best results…it even raised sperm motility and allowed me to get my wife pregnant and we are expecting within the coming months. However, I was hypersensitive to the clomid, my LH at one point soared to 32. While on 50mg nightly and .5 tab Arimidex daily my T peaked at 800+ but E2 was 45 and Free T was below the reference range (1.2%). I cut the dose to 25mg and T remained elevated in the high 700’s but e2, LH and Free T were unchanged vs 50mg.

    Not asking for personal advice, as I am not longer taking Clomid due to the estrogenic side effects and lack of increase to Free T, but generally speaking, how do you counteract the typical spike in SHBG and estrogen levels and the corresponding drop in free T? While I liked Clomid (and think Androxal would be a great alternative) the estrogenic side effects seem nearly impossible to counter and render any increase in serum T useless based off the weak Free T levels. Maybe something stronger, such as Letrozole would work better than A-dex? I’d be interested in your opinion as you seem well versed in using alternatives as it seems too many docs today are quick to proscribe Androgel or Cyp as a band-aid rather than trying to help solve the actual problem at hand.

  • Michael B

    hey Dr. Miller, So ive been on Clomiphene for almost 2 weeks already, tomorrow marks the second week and this is how it went.. The first 3 days I felt no difference but when i woke up on the 4th day, I felt my sex drive rise completely and my testicles grew, it was like a rush. This feeling unfortunately lasted 6 days until i woke up on the 7th feeling drained, had no urge of getting out of bed and my sex drive completely diminished. Ive been feeling like that since, weak erections and all. Im 21 years old, taking 25 mg of clomid every night before bed and my last total testosterone lab results were at 363 when it should be at 700. Im healthy and I work out every day. Ive done some research and i read a lot of posts by people saying that clomid is a libido killer. Now my question is, should i lower the dose of my clomid intake? and by that, i mean by, taking 25 mg every other day instead. Is this normal and how long will it take to notice results? Im just scared if my body is telling me that 363 is my permanent level, I really dont want to jump on TRT because of the side effects.

  • sss

    hey feel much better in just 9 days of taking clomid. ed is resolved, moods better. thanks dr. Miller. forced my doc to give clomid after reading this blog.

  • john m

    Hi doc I have been using clomid 25mg daily for 16 days I feel increase in strength but libido is gone , I still can have sex but it doesn’t feel good as it used too even if I refrain from it 2 or 3 days .Before using clomid it wasn’t like this so should I stop or give it more time. Dr. Miller: You need to see a knowledgeable doctor and get blood testing, and consultation. Your estrogen levels may be rising too much, or there may be another problem.

  • ahsan

    Hi doc, I am 20 yr old.i have been diagnosed with low t for about an year which averaged 270 in about four blood tests taken every three months.Recently got fsh,lh and estradiol which where

  • VK

    Hi Doc,

    I am 28 years old. I have T levels ~280 ng/DL. My LH/FSH levels are normal 4-5 range. Sperm count ishealthy , barring few puss cells (7-8/hpf), for which i took Doxy. I was on HCG Therapy for 2 months and levels reached 500. My only symptom is ED and i otherwise feel healthy. What medication will you recommend in this case ?

  • Darren

    Hi doctor after a long spell of feeling crap low energy brain fog low libido poor erections . I was watching a program on TV the guy was pretty much spelling out my symptoms. And he had low T I decided to get my doc to test me she said yes low T was the result now when I went out see specialist he tested me and told me it’s not that low which took as low he give me any details anyhow been on tesogel for past 2yrs and finding need to up the dose. What surprises me is that neither doctor seemed to want to get to the bottom of the issue. I wouldn’t have thought a 43 guy physically fit not overweight would have low T unless there was an underlying condition anyhow on reading about this problem. Decided to give clomid a go for a couple of months see if it helps and report my finding to doc but am worried they will take a dim view and won’t help me. What do you think.?

  • Scott

    Hi Doctor I am 38 and have been on Androgel for 3 years. My T levels are good but I get stressed so easily. This didn’t happen the 1st few years it just started in the 3rd year. I suffer from depression and anxiety. I run a large company with lots of stress. I am also a chronic Marjuana user. Do you think I should try going off of androgel and convincing my doctor to put me on the meds you are referring too? Please let me know.

  • s k

    Hi doctor i m 43 years having sperm problem due to this my wife can not conceive last nine years can i take clomid plz tell me due to this my sperms increase and my wife conceive

  • RJ

    Hi Doctor miller,

    I was recently prescribed clomid by my doctor. I am currently experiencing adrenal issues and low FREE test. My Free test is 9. My total is about 500. I have been experiencing poor mood, no motivation, terrible fatigue, anxiety. Would clomid be helpful? My eye sight has declined in the past few months. Would clomid worsen my eyesight PERMANENTLY? I took Propecia for several months but stopped due to low libido. Now i am terrified of taking anymore hormonal meds. How do i know if you respond back? Thank you for your help.

  • RJ

    Hi Doctor miller,

    I was recently prescribed clomid by my doctor. I am currently experiencing adrenal issues and low FREE test. My Free test is 9. My total is about 500. I have been experiencing poor mood, no motivation, terrible fatigue, anxiety. Would clomid be helpful? My eye sight has declined in the past few months. Would clomid worsen my eyesight PERMANENTLY? I took Propecia for several months but stopped due to low libido. Now i am terrified of taking anymore hormonal meds. How do i know if you respond back? Thank you for your help.

  • rrk

    Hi Doctor, i have used CC for the last 1 year for hypogonadism. I responded to it very well. However, in the last couple of blood tests i had high LH levels (0.3points more than the max). the PSA levels are constant. is this a problem? should i switch over to testosterone? I am otherwise very healthy;

  • Fuad

    Hi doctor, I was diagnosed with low t. My total t was was at 170 but doctor was telling me that everything else looks to be on normal range. I barely can get an erection, my entire body hurts especially my joints!!! Painfull urination and bi went to urologist and he gave me some over the counter med for uti.. Finally I asked my endocrinologist to prescribe me clomid and he did . I am taking 25 mg every other day! How long do u think it’s gonna take for me to see some positive result? Thanks

  • Marcio-brazil

    Hi doctor… Only 1 injection of deposteron (testosteron) can cause testicular atrophy? Dr. Miller: I doubt it, but it may be possible.

  • karim

    Hi dr miller

    I’m a 38 years old male from Egypt

    I was suffering from varicoceles since i had 20 years old with no impact throughout this years on my fertility neither on motility or simen count …etc

    Few months ago i went to check my testosterone and it was in low level area ( free and total ) accordingly i decided to deal with case through varicocelectomy with microsurgical approach and thanks God the opeartion wad successfull

    After the operation sperm count still great as it wad before the operation with a slight increase from 132000000 to 140000000 in addition to slight increase in total and free testosterone but with no significant improvement on my sexual performance ( still suffering from erectile disfunction till now )

    My question….Dr want to put me on hcg treatement plan of two month only during which i should inject a dose of 5.000 IU of HCG twice per week for 8 weeks ( means a total of 10.000 IU per week ) my question ; would this amount of HCG during 8 weeks cause any kind of dependency so my testicules will not be able to respond n normal LH ?? And if yes can i reduce this dose to be 6.000 IU per week instead of 10.000 ???

    Last question. In such case do you think that after two month of treatement i will be able to stop hcg and my testicules will continue to produce normal testosterone to reach tbe normal level.???? Please advise

  • Sunny

    Hi Dr Miller

    My LH is low normal 2.5 and FSH is normal 4.5 (ref range is 2-7) and I am hypogonadal for almost 2 yrs diagnosed by Endocrinologist, MRI(Pituitary) Normal and 310 Ng/dl Total Test. and free is less than 0.5%.

    I tried Nebido 1000mg/4ml and in 4 weeks my body metabolizes it and I feel low and fatigued and muscle soreness after gym session that lasts for 4 days of every workout.

    Unfortunately I am on every 8-10 week Nebido *Testosterone Undecoanate) and that’s not enough as my body using it all up in about 4 weeks. What other treatment options I have so I can take your suggestion to my Endocrinologist so he could help me please.


    LOW T and Low LH is consistent with Blood tests (Tested 5 times) in morning.

  • Bobby B

    Hi Dr Miller, first and foremost I just want to say thanks for the great article, really informative yet easy to understand!

    I just wanted to ask if there are any long-term side effects of using/stopping clomid. I read the four points that you mentioned, but was wondering if there are any more. For example, if you use clomid to stimulate test production via LH secretion for say a period of a year, would it be expected that once you stop treatment, your LH levels hence test levels will fall below your previous baseline due to being stimulated for such a long time?

    Simply, what I am trying to ask is, once you stop clomid treatment, will your test levels fall lower than they originally were or would they reduce only to their original number?

    Another quick question, is clomid a safe treatment for younger males, say 21 years old. I know that doctors are hesitant on writing young males TRT due to HPTA suppression which many potentially restrict its development. As clomid also effects the bodies natural hormone balance, is it still safe for young males?

    Again, thanks for the great article and taking the time to read my questions.

  • Harry UK

    Hi Dr Miller, great web site very informative, I’ve been reading previous post by others and I have had a similar experience as Matt UK

    We are the same age, suffered with similar symptoms but main complaint having ED with pretty much the same blood test results. I was seen by a NHS endo and was told visually I looked normal, my ultrasound scan of my testes came back fine as well as my MRI scan of pituitary gland and was also told to see a sex therapist and that my test should go back to normal with time also felt insulted and let down.

    I have tried everything possible to bring myself back to normal naturally have asked about clomid but having trouble getting doctors to prescribe it ? Where can I get it from??

  • Chris

    Hi Dr Miller, im a 26 year old male who after taking finasteride i developed what seems to be permanently low T levels. My question is have you heard of clomid helping with people in my situation. Im fit and active and dont understand why after taking the drug my t levels never went back to normal. strength and frequency of erections have also slowly gotten better but it seems like my low t is stopping me returning to normal. Any help would be appreciated. Thank you. Dr. Miller: I’m sorry but not sure if clomiphene will help. Check out Good luck.

  • Wendy H

    Hi Dr Miller, what an I interesting article! Why not use HCG in the direct or homeopathic version, currently so popular and effective for dieting?

    All best,

    Wendy H

    Ex LA now France

  • Dave

    Hi Dr Miller. My doctor put me on Clomid (50 mg every other day) as a result of secondary hypogonadism. Within a week on the medication, my skin became extremely oily and I started developing terrible and painful acne like I was 16 again. I understand that this is likely a result of elevated androgens including testosterone, DHT, etc. My question is whether this will likely subside as I continue treatment and testosterone stabilizes at a higher level? In other words, is this likely a result of the initial increase/change in hormone levels, or just elevated levels in general? Curious what you have seen in your experience with prescribing Clomid to men. Thanks.

  • David

    Hi Dr Miller. Thank you kindy for your website, it is great! Question – is mood swings/anger a side effect of getting the clomid dose correct for some men?

    • Thank you! Most men don’t have such a side-effect, however any medication can cause any side-effect so if you are noticing something different, please talk with your doctor.

  • Dav

    Hi Dr Miller. Great blog, very informative. I’m a 43y old male suffering low Testosterone symptoms. My Dr ordered blood tests after which I researched HRT and came across various options including Clomid. My Dr seemed to want to prescribe Test cream but I mentioned Clomid. He had heard of it but wasn’t sure. A week later he prescribed some at 50mg for 7 days then 25mg per day. I’m not sure he really knows a lot about it and don’t want to go to another Dr as from what I hear they don’t like prescribing Clomid. My question is with regards to side effects. Is my Dr on the right track here and how long can I stay on it without experiencing those side effects like eye damage or any other dangerous side effects. Thank you.

  • Sam

    Hi Dr Miller. I am a 30 Year old male and have erectile dysfunction from 3 years. My doctor recently diagnosed me with vanogenic ED, and has prescribed Clomiphene citrate 50 mg daily for 6 months. How long would it take for Testosterone levels to rise (given my T levels were lower limit normal). How effective is clomiphene in treating venogenic ED? Thanks a lot.

  • Chris

    Hi Dr Miller. I had undescended testes cooking in my groin until I was ten. I have a sperm count that is the envy of vasectomy seeking studs! Basically, I have known I have useless chestnutsticles and low T for many years. I just never connected the dots with symptoms… nor did any doctor. Am I wasting my time with Clomid? Or could it have a positive effect in my circumstances… thank you, Chris

  • Agha Rameez

    Hi dr sahib could you tell me about my FSH.because have low fsh which is < age is 25 so tell me is it serious for me or just do as doctar say

  • John coleman

    Hi Dr. I had a reversal done 7 months ago sperm test shows that the op was a sucses but stil have a low spermcount of under 5 milj.I had the reversal done not even a year after the vasectomy im 34 years old will clomids help my spermcount .

    Thank you

  • Syed

    Hi Dr. I have low T & high FSH and my sperm count is zero where as my scrotal scan is normal. Me and my wife are trying to conceive for past 18 months without any result. I have normal sex life with normal erection and all. Will Clomid be helpful, please advice? Dr. Miller: That depends on the cause of your low T and high FSH, and what “high” FSH actually is in this situation. There may be a genetic reason for not having any sperm. You need to go to a fertility clinic, and they can always do a trial of clomiphene to see if it works.

  • Adam

    Hi Dr. I have problem I am a bodybuilder and I was last 4 years on testosterone , last mount I had hard attack nstemi tropinin level 70 dr. Give me treatment aspirin..clopidogrel..bisoprolol..ramipril..atorvastinin.. I start to feel my testosterone is decreasing and I want to take clomid..nolvadex..hcg..but I don’t know if is safe to take it after heart gp can’t answer me.. Please can you help me..

  • Sunny t

    Hi Dr. Miller ,

    Last year I was diagnosed with a pituitary adenoma, specifically prolactinoma with levels near 80. I started cabergoline .25mg a week and 4 wks later level dropped to 25. Dose increased to .375 mg and levels dropped to nl. They have been normal for 5 months. However, my free testosterone came up a bit, but very low. Before my doc started clomid or hcg to get testosterone up, I had semen analysis. My wife and I want to conceive our 2nd child. My results came back as normal, except the morphology which was 12%, above 15% is normal. Concentration, motility, ph, etc was normal. Motility was 41%, above 40 is normal. What are the differences between hcg and clomid when it comes to semen quality?

    Thank you

  • J

    Hi Dr. Miller

    My endocrinologist has me on 50mg of clomiphene currently. It has been about 6 months and I have had a lot of headaches and I’m suffering from lethargy. I go for blood work soon to check my T-Levels, previously they were down in the 400 area and my endo said my LSH and FSH were also low. Is it common to have headaches and feel lethargic on clomid? Would HCG have less?


  • pd

    Hi Dr. Miller, I was diagnosed with low T and was given Clomiphene (50mg). I was also just diagnosed with Sjogren’s syndrome, and autoimmune disorder. I am experiencing a lot of pain in my belly and penis when I have sex. I cannot ejaculate without pain. Could the Clomiphene be affecting this? Thanks!

  • Meredith

    Hi Dr. Miller,

    My husband had been on testosterone injections every 2 weeks for a T count around 70 for the last 5 years. His Endo and Uro have no idea what’s wrong with him, as he does not have a tumor, and does not have erectile dysfunction. He is 28. We are trying to get pregnant, discovered he had zero sperm, and is now on Clomid. It has been 3 weeks since his last injection, one week on the Clomid, and he feels terrible, similar to what he felt like prior to injections: exhaustion, general malaise, dehydration, inability to concentrate–he’s like a giant space cadet. Any idea how long it may take for the Clomid to stimulate his testosterone production? I know there’s a risk it may not do it at all, but if we’re lucky and it does, I just want any kind of time frame to help him through it, so he can think “I only have to be in a funk for 2-3 weeks instead of the entire time” on the Clomid, which is when I get pregnant. After one week on it he wants me to be pregnant yesterday so as to get back on his injections. Thanks for your help. Dr. Miller: The effects of clomiphene can take several weeks to feel. For sperm production, waiting at least 3 months is usually necessary. HCG may help too. Stopping testosterone overnight is not recommended. Seek a second opinion for the cause of his low T. Good luck!

  • Kyle

    Hi Dr. Miller, I am a 27 year old male who used propecia for 5 years for hair loss and have been experiencing loss of erections both morning and nocturnal as well as spontaneous. I can only get them through physical stimulation. I have been to post fin help site with no current updates. My FSH was 1.9 (1.6-8.0)for reference, my LH was also low and my total test was 473 (250-1100) for reference. I was prescribed 25mg Clomid once daily as well as 1mg Arimidex once per week. I am scared to take the Clomid hearing about the side effects of libido crash and ED and not being able to achieve an erection even through physical stimulation, plus the vision changes and gynocomastia. Also would these side effects be permanent or subside with discontinuation? Have you had any success treating any patients with pfs? Any suggestions or input is much appreciated. Thank you!

  • Nathan

    Hi Dr. Miller, I am considering taking clomid to increase testosterone. I am 25 years old and I had my levels checked and they came back 18nmol/l (519ng/dl).

    I was treated as an 18 year old for delayed puberty (had 3 monthly injections but I don’t know what they were)and the doctor said my levels recently are in range so there is nothing to look for.

    I have never had a sex drive (very occasionally I have one) and very little facial hair and that’s why I thought I would have them checked as it was I didn’t want it to affect my relationship with my girlfriend.

    I am also an athlete so how long would clomid stay in your system for? This isn’t for a performance benefit. Thank you.

  • Jason W.

    Hi Dr. Miller, I am writing to find out your take on the difference on clomid and the new drug androxal. I know that androxal is 1 active isomer versus clomid’s 2 isomers but I am not sure if there will be a benefit of the new drug over clomid. I am also wondering if the new drug will not have the elevation of estrogen like clomid can. Thanks

  • Peter

    Hi Dr. Miller, I have been on Clomiphene 25 mg/day for 2.5 years. My T level started at 390 ng/dl and has increased to 675 ng/dl, with 25 ng/dl free. I love this drug! I feel so much better in many different ways. Over the past few weeks however I feel the drug has stopped working – sleep issues, rare nocturnal erections, fatigue. I questioned whether this particular batch of the drug was not effective so I have ordered another prescription. Have you ever heard of something like this? Also, where do you practice medicine? I live in the Boston area. Thanks.

  • Bob

    Hi Dr. Miller, I started having low libido and lack of sexual energy two years ago due to hypogonadotropic hypogonadism. After seeing an endocrinologist last year, I was started on Clomid 50mg daily for 3 months. While things didn’t get back to normal, they got at least 50%-60% better (performance was back to normal, but libido was not). However, my symptoms reverted back after discontinuation of Clomid.

    My doctor then put me on 50mg Clomid once a week as an indefinite measure. However, after 3 months, I reverted back to pretty much original symptoms. Since then, my libido has been fairly erratic–sometimes helped by Clomid, sometimes not. Do you know of any reasons / solutions? Thank you! Dr. Miller: Usual maintenance dosing of clomiphene is daily or every other day. Also, if estrogen levels are too high it can decrease libido or cause other problems.

  • mike shields

    Hi Dr. Miller, I’ve struggled with very low T (150-250)for the past 2 years. I suggested Clomid to my Dr. and have been on it for the past 4 weeks. Testosterone just retested at 448, wow! Question… does this help to determine if my problem is primary or secondary? FYI, I also have problems with varicose veins and my urologist has verified that I have varicose in my scrotum. So is it possible I might also benefit from having those veins surgically repaired? Or do my results point to a problem with my pituitary (had an MRI of my brain about a year ago, results show no pituitary tumor).

  • worriedwife

    Hi Dr. Miller, my husband has been on trt for 5 years, he never had low T, just a need to bulk up, but is now dependent on it. Can he switch to clomid and if so, what side-effects should we anticipate from the switch. Dr. Miller: Yes, clomiphene (and sometimes HCG is necessary too) can bring testes back to life. Side-effects are in article above.

  • Chris

    Hi Dr. Miller, Not sure if you still follow this blog, but before starting Clomid, my Total Test was between 270-350. Started 25mg/day Clomid; was up to 700 within a month, and I felt great. After another month, my T levels dropped to below 400, and then below 300. My Estradiol didn’t change between labs, and my LH and FSH are elevated per what’s expected from the Clomid. Nothing suggests testicular damage; any thoughts on either where all the Testosterone is going, or why I stopped producing while still maintain high levels of LH?

  • Peter

    Hi Dr. Miller, sorry I have one other question if you have a moment. I currently take Clomid. Do you have an opinion on what dosage is more effective – 25 mg/daily, or 50 mg/3x week? Thanks.

  • Amari

    Hi Dr. Miller,

    I was diagnosed with non-obstructive azoospermia in 2012 and during this diagnosis, it was learned my testosterone levels were at 190-210 range. Doctors still say they are not sure if there is any connection with the azoospermia and low-T. Anyway, i had micro tese procedure done on both testes which further reduced the size of the testicles. My doctor is not a fan of any gels or injections and he suggested I take half a clomid pill (25mg) everyday. I’ve been doing that for about a year now. My T levels have gone up to 300-400 range but def. not to 500 – 700. Is this because the testes are too small now and can’t produce enough T or my dosage is too small? What are you thoughts on continuing with Clomid? I def. feel less tired than before but I think I can feel a little better..

  • Jason

    Hi Dr. Miller,

    Yesterday my Endocrine Dr. prescribed this to me. but my issue goes back pretty far. I am 39 and I recently had a pituitary tumor removed. I found that tumor as a result of looking at my low T. I hated the effects of TRT and asked my doc about low-dose Testosterone and he prescribed Clomid. The lesson I learned here is that Low-T may well be a sign of something much worse and as men taking Testosterone should be considered a secondary result of proper diagnosis.

  • Paulo

    Hi Dr. Miller. Are there any risks of cancer (like thyroid or pituitary gland)? I am on Clomiphene (25 mg every day) and feel great. I love it.

    • I don’t believe there are reports of clomiphene citrate causing cancer in men. There are mixed findings about CC in women and ovarian cancer risk.

  • Paul

    Hi Dr. Miller. Great blog with some great information. I recently saw my endo and he has perscribed 25mg of clomid eod. I have decided to instead, go with 12.5mg eod since it seems that dosing too high causes libido issues. My question is whether you think this regime will help to restore my low libido. I will also be taking anastrazole at 0.25mg per week. I may switch to a newer drug called aromasin but will wait. What is your opinion on this new AI? Lastly, do you have any opinion on the use of HGH for anti-aging increasing testosterone purposes? Thanks

  • G

    HI Dr. Miller. in previous answers you seem to give contradicting knowledge about clomid and its effect on shbg. I understand that estrogen will increase with clomid if you are over weight, however, what is the effect of clomid on shbg? Will it rise and cause a drop on Free testosterone or will it actually be beneficial at a low dose and not raise shbg?

  • john h -propecia syndrome

    Hi Dr. Miller: I am a 61 year old man in good health. When I was 45 I was prescribed propecia for hair loss, 1mg/day. I had a temporary drop in libido and then it went back to normal where it remained for 15 years, while still taking propecia without problems. 16 months ago I went off propecia and noticed a marked decrease in libido. I have read that this is post finisteride syndrome. It may or may not be permanent. Can you recommend a treatment with clomid? I am located in central Florida. Thanks john

  • Tim M

    Hi Dr.

    Wanted to ask if you put one of your patients on clomid do you recommend a certain time of day that its best to take? Like mornings or preferably evenings? And better on an empty stomach or after eating? Thanks.

  • Ryan S

    Hi I am a 30 year old healthy male that as been taking testosterone injections (steroids) on and off over the last 8 years, Me and my partner have been trying for a baby for over 18 months when I got a fertility check I found out I have 0 swimmers. I have never took anything to kickstart my own test, will clomid help improve my motility??? please help Dr. Miller: Yes, it definitely could.

  • Gary Smith

    Hi if you re looking for clomid try I orderd there

  • Jay V.

    Hi im a 29 year old male suffering from low T. I was first diagnosed by my urologist after I realised I was having getting an erection or maintaining one,My endocrinologist did a full physiological check blood tests MRI etc and concluded that I was perfectly healthy except that my T levels were in the lower ranges, avergaing 4.46 ng/ml

    he in fact told me that the relationship i was going through was the cause and it was all due to stress(I was in a relationship that ended badly) was nearing depression. Since then i have been very lazy and tired most days, have lost significant strength in training and still having problems having an erection(I have never had such a problem before that) It now been two years since diagnosed with low T. My question is what should be the range for a healthy male at my age and if using clomiphene could raise my test levels, and also could my erectile dysfunction be as a result of the low T that I am experiencing?

    I am patiently awaiting your reply,sincerely Jay. Dr. Miller: Jay, yes definitely low T can cause erectile dysfunction. Yes, clomiphene could help. I don’t focus on a specific testosterone level, but in general try to be in top 30% of range of normal, or according to symptoms. Hope this helps.

  • Mehdi

    Hi Ryan

    of course you need a kick start try clomid it may help you to bring back testosterone to a normal range

  • Debra

    Hi there just stumbled upon your blog via Yahoo after I typed in, “????” or perhaps something similar (can’t quite remember exactly). Anyways, I’m glad I found it simply because your subject material is exactly what I’m looking for (writing a university paper) and I hope you don’t mind if I collect some material from here and I will of course credit you as the source. Thanks. ??????????? ?????? ? ?????????

  • Na


    If a man stops clomephene after a course of three months, will the increased testosterone stick? What are the results from study revealing ? What has been your experience? What are the possible factors that could help with sustaining the higher testosterone?

    Dr. Miller: It depends. Primary cause of secondary hypogonadism needs to be addressed and fixed if possible. Also, age is a factor. If a man is young, and cause of secondary hypogonadism has been treated effectively, then yes the testosterone levels may remain elevated after discontinuing clomiphene.

  • Paul K

    Hi, 36 year old male. Abused prescription pain killers for 3 years and then was on suboxone for 3 years. Been off everything for 3 months but noticed no sex drive, lack of energy, and generally no motivation. Went to my doctor and found my test to be 184. I know I’m still healing but will my test stay low or will it eventually return to a more normal level. Would clomid be something I should consider in the meantime. Thank you for any advice. Dr. Miller: Yes, your testosterone may increase on its own as your health improves, but clomiphene may help accelerate the process.

  • Rayan

    Hi, I am 28 year old and I am married. Around 6 months ago me and my wife went to specialist because we had sex once everg month or every two month. The especialist did ghe blood test for me and told me that I have low testostrone maybe because of stress or some reasons like that and he prescribed me CC. Now, after around 6 monthes I have hairloss in my body. Is this the side effect of the CC and what do you recommend?

    Also I have another question, I consult with one other specialist in my country and he told me that it is impossible that you have low testostrone because you had mustache and bear from age 15. I am confused please help me.

    Thank you so much

  • Ahmad

    Hi, I am from India. How can I seek your advice.

  • Bleck

    Hi, I want to use clomiphene to increase T levels. Not having some very low T, but would it harm to use it for bodybuilding purposes, with no particular issue? THanks

  • Bleck

    Hi, I want to use clomiphene to increase T levels. Not having some very low T, but would it harm to use it for bodybuilding purposes, with no particular issue? THanks. Dr. Miller: I don’t recommend using clomiphene or any other drug for doping purposes.

  • dang

    Hi, im a wife who is very much worried of my husband’s condition…we went to a urologist for low sperm count treatment…he prescribed clomid 50mg bid…he has been taking the meds for 10 days now and notices a big changed. he cannot achieve an erection. Dr. Miller: He may be converting the testosterone to estrogen. He should tell his doctor about this.

  • JJ

    Hi, is Clomid the right treatment after 8 weeks of testosteron injections, once a week (2ml of 250mg/ml).

    To bring back my natural production of testo? What is the right doses (25/50mg) per day? and how long.

    Or were the testo dosis so low, i can recover myself? I’m a male of 47 years

  • Julie

    Hi, my husband has low testosterone and is only 28 years old. He has had testosterone injections which did nothing and he has now been told to go on Axorin. I do not want him to go on that as we hope to have children soon. I feel your information gives us something new to work with. Could you please tell me whether it is required that HCG is required to go with Clomid or if Clomid can be used on its own. How long does it normally take to see any improvement in serum levels as well as in symptoms such as low mood, poor energy with this?

    Thank you! Dr. Miller: Clomiphene can generally be used alone. It all depends on cause though. Usually symptoms improve in a week or so, but they can take a few months to optimize. Also, if testosterone injections didn’t help, there may be another problem.

  • Vasek

    Hi, my total T , FSH and LH levels are normal but I have these problems:

    – low libido

    – insufficient erection

    – oligospermia

    – increased SHBG

    – lower free testosteron index

    My urologist thinks that 50mg Clomid per day might be a good solution for all these. Is it a wise administration?

  • Sparky


    What will the result be of taking Clomid either 25mg/50mg per day (whatever has been prescribed as best by a doctor) with the addition of Arimidex (Anastrozole) at a dose of 0.5mg twice a week? Would this cause more free testosterone to be available, and less of a conversion of the increased testosterone by the Clomid to Estrogens/Estradiol? Thanks. Dr. Miller: Yes, and an increase in total testosterone.

  • Chef Art

    Hi. I am a 62 yr old male who works out with weights 3-4 times a week. Gaining strength and muscle mass is my main desire. Haven’t had my testerone tested.

  • Jefferson

    Hi. I had orchiopexy for one testicle around age 2, and now at age 36 I realise that my former doctor, since I was 6 months old has been negligent, since I have been complaining of tiredness and shortness of breath for the past 20 years or more. I accept my naivity also. I hve done severl annual medicals, and in 2011, one doc asked me if I knew I was anaemic for at least he past 7 years of medicals I had, but I did not. Now after after years of successfully falling asleep at work, home and almost fatally at the wheel, thanks to sites like this one, tested and found out about low T and the causes. It gets me angry and at times sad, since I think of the side effects which I see have manifested in my life. Unanswered questions now pieced together like a giant jigsaw puzzle. Poor memory, low energy, confusion, inability to keep weight off, weak erections…. I even went to a urologist for a prostate infection, and he said “These don’t feel like healthy producing testicles”, but I dismissed it since he did not suggest any tests or seem concerned enough to probe deeper than my first digital prostate exam. Plus, my wife got pregnant shortly after… so silly of me. I am currently taking DIM extract an have increased mt zinc using 10 pumpkin seeds per day, and plan to try maca root, as an natural alt. to testosterone injections. I have notes less tiredness and have a feeling of more activity (slight tingling sometimes) in the normal testicle. I am to recheck my T level shortly. If it is still low, can I try the CC, and is there any way to stimulate T production in the abnormal testicle. Also, are there any concerns you might have with this situation? Dr. Miller: Thank you for appreciating this website. There is no harm trying clomiphene. Orchiopexy shouldn’t damage the testicle. And you also still have healthy testicle.

  • PMC

    Hi.. ive been taking Clomid for 2.5 months now. I used to take Test/HCG but we found my sperm count to be zero. 25mg/day.. I hope this works.

    my main complaint is the loss of libido. Is that a side effect in men? Anything I can do to counteract? Dr. Miller: Loss of libido may be due to testosterone conversion to estrogen.

  • MAG

    How do I know if my hypogonadism is primary or secondary? does Clomid help any for primary hypogonadism? thank you in advance for your kind reply.

  • ML

    How long can one take Clomid? Can it be a long-term solution? My endo suggested trying it, but said it’s only a short term solution, and that if low-T recurs we would have to try something else. (I am 52 yo… Currently T level bounces around between 200 and 160… LH and FSH are “normal” at about 10.6 and 18.0 respectively… I am not overweight at 5’10” and 178 pounds with a BMI of about 26)… She thinks low-T is a side effect of chemo for Hodgkins when I was in my 30s. I am interested in Clomid, but just want to know how long I can take it… could it be a long term solution if it works?

  • Jason

    How long does it take for clomid to take effect? Dr. Miller: It can take 4-6 weeks for full effect.

  • Tom

    How long does it usually take to see effect of clomid? My physician prescribed 25mg every third day for low t (secondary) my total and free t went up around 40 pct after one month from baseline testing, will this continue to increase or does it typically level out at a certain point? If it levels out but I still feel symptomatic do you suggest asking my doctor forincreased clomid dosage or adding Hcg

  • Mark

    How would you assess the risk of lowered SHBG in a male patient with age-normal testosterone (free + utilized) started on clomiphene 25mg EOD? Also, how long after treatment initiation would labs for E2 be necessary to obtain? Patient is 30 y/o with no relevant history. How does DM2 change this picture? Thank you in advance for answering my question. I am trying to get a better understanding of the feedback mechanisms involved here based on your clinical knowledge and experience. Dr. Miller: SHBG will likely rise with increasing testosterone level. I prefer to check at least estrogen and testosterone levels about 4-6 weeks after starting clomiphene. Type 2 diabetes can cause secondary hypogonadism.

  • Rahul krishna

    I am 30yr old male was on testosterone for last 5yrs, stopped 2months back, now have small testis, low libido, easy fatigue, ED, I am taking hcg 2000iu twice a week is clomiphene going to help? Can I take both clomiphene and hcg both simultaneously is der any harm thanks

  • krazykrip

    I am 33 yrs old and I had a T-level of about 200 last year. Saw a doc since I had mild gyno. Did an MRI and found out that I had secondary hypogonadism due to empty sella syndrome (saw an endo and neuro to rule out any serious causes). After requesting my doctor to try clomid, I started on a low dose of 25mg every other day and within a few days my levels rose to the 700s. I did have morning erections the first few weeks but that reduced after that. I have been on clomid for about 6 months now. T-levels are high, but gyno has not improved. All other levels seem normal (PSA, prolactin, estradiol). We are planning to stop Clomid later this year and see if my T-levels stay high. If it drops after I stop Clomid, my endo prefers to start me on Testim. In your experience have you seen any patients where t-level recovery remains after Clomid stops? Also, I have been reading on the potential vision issues with clomid and have been freaking out (since some seem to be permanent). How common is this side effect?

  • john

    I am 35 old male working as AP in University and recently got married in may 2015 before marriage i was feeling sexually well, good libido,good erection always having desire for sex. After marriage in early days i suffered from premature ejaculation and erectile dysfunctionality due that stress i consulted sex specialist ,initially he prescribed medicines(taladafil) for performance anxiety.But when the problem repeated he advised to check testosterone level .After test initially it was very low 132 ,in 2nd test after a week it was 220 before four months ago.I

    reported to some endocrinologists they ruled out any testicular failure.I tried some herbal medicine like shalajeet but no results.I request your good self to advice me about the treatment of this problem my life has became hell i always think only about this problem but not getting any solution.

  • ER

    I am 48 yrs old and had a stroke while taking testosterone. The stroke work-up has been negative and all my doctors are saying that the testosterone was likely a causal factor. Do you think that clomid would be a safe alternative?

  • sae

    I am 52, in 1986, I underwent the process of lifting varicose testicles, sperm count per CCM 100,000 or less, medium or weak movement. Clomid pills dealt with for a year and then my wife gave birth to a girl in 1988 and gave birth, born in 1991. In 1998, underwent the process of lifting varicose testicles again and took Clomid pills for about six months, in 2000, my wife gave birth to a boy and in 2002 gave birth to a son. In 2012 I consulted a doctor about varicose condition of the testicles has told me that it does not exist, but the number of sperm become less than 70,000 per CCM. Dr. Miller Do you recommend eating pills Clomid now for procreation Is there a risk?. What do you recommend. Thank you. Dr. Miller: Yes, Clomid can increase sperm count.

  • thorflea

    I am 53 and been on clomid for over a year now. It has increased my T from 129 for around 800 @ 25mg/day. When I was on 50mg/day my T was 1300. I have 2 problems now:1)my desire level has not improved, 2) my PSA level have gone from 3.8 to 5.0 in the last 18 months. In some ways I feel fantastic and been hitting the gym every day. Down to 11.5% body fat.

    My question is at what point do I stop the clomid if my PSA does not fall back in line?

  • Shah

    I am 55 mg methadone and going down 1mg a week till I feel the withdrawal and maintain and start going down again. I feel like I’ll be on the methadone treatment for a little while longer till I can comfortably come off of it. Can I use clomid for my low testestrone ive been researching about TRT and I am 27 years old and want to have a kid soon. Will clomid work for me and can I use it with methadone.

  • nelson

    I am 65 with enlarged prostate can I take Clomid

  • B

    I am a 22 year old male who has low T from steroid use. I want to restore my testosterone to naturally high levels, and I am seeing by research that HCG with armidex and test cypionate or androgel is popular and getting good results. Will I be able to restore my test production back to normal after 8-12 weeks of treatment of this? Any advice would be greatly appreciated. Thank you. Dr. Miller: Yes, testes can come back to life, and in general I recommend clomiphene or HCG.

  • rw

    I am a 39 year old male. I was diagnosed with low T and started clomid about 2 months ago. I have nearly doubled my T count and have noticed the extra energy that I have started working out for nearly 2 hours everyday after being very overweight with no energy to workout prior to the clomid. Unfortunately, although I’ve had increased energy I have also started adding pounds faster than at any other point in my life – in the 2 months of clomid and gym workouts I have gained nearly 20 pounds:( Now my new blood tests show that in addition to raising my T count that I also have raised my estrogen count and I am starting on anastrozole. Could the increased Estrogren count explain the weight gain and could anastrozole lead to a reversal of this weight gain as long as I continue working out. Very frustrated:(

  • HR

    I am a 41 year old male, diagnosed with Low T 11 months ago. I was having NO problems with erections or libido, which is why it surprised me. My urologist immediately put me on Clomid. Levels went from 195 to 800 and have stayed there. Everything was great, erections, how I felt and energy. Bloodwork recently showed estrogen at 68 and he wants it below 50. He put me on Arimidex 1 mg per day. I could not take the full dose due to some crazy side effects, so I took 1/4 pill every other day. Immediately erections and libido went down. Any advice? Is the estrogen level too high? Should I reduce the clomid 25 mg to every other day? Thank you.

  • Wodan

    I am a 44 year old man in Holland and have low T (250) diagnosed by a doc. I have been described clomid 25mg ed for a min of 3 months.

    – What dosage do you recommend?

    – What about the lower IGF-1 levels with clomid use? This is researched in women.

    – I have use letrozole before and it brought my T to 800. However I suffered pain in knees and loss of libido! Energy was great. T dropped after discontinuiing to 250 again.

    – What do you think of Triptorelin 100 mcg injection?

    Thank you very much for your response. Dr.Miller: I’m sorry but I cannot give personal medical advice here. I have not seen clomiphene cause low IGF-1 in men.

  • Bruce D.

    I am a 45 yr old male with low T and have taken injections on and off for 3 years now as my pretreatment T level was 212. I can take injections 2x weekly and get my level up to 800 but once I stop the injections it falls back to 200+/- after 2-3months. Would clomid be a better choice for me?

  • v

    I am a 55 yr old male. Started taking clomid last August to raise T levels. Just had my blood test and T levels have increased to a normal level but my PSA was .6 and it is now 9.4 No prostate cancer in family history, Dr told me to stop the clomid and have PSA level retested in 3 months. Does clomid or the increased T levels cause PSA levels to jump. Dr. Miller: When increasing testosterone level (whether by using clomiphene or testosterone)causes PSA to rise then prostate cancer needs to be ruled out.

  • dan c

    I am a 65 yr old male in very good health. I work out about 5X/week. My T level is 275. I plan on taking 100mg of Clomid for 3 days and 50mg/day gor 60 days. What would you recommend I do after that? Dr. Miller: I can’t give personal medical advice to you without you being my patient. And, I never recommend using clomiphene without physician supervision.

  • Dave

    I am a 68 year old male.I have been on Fimasteride for several years, and have been on Fimasteride for several years. I have had trouble getting, and maintaining an erection for a while now, as well as decreased ejaculation. Will Clomiphene help my situation?

  • John R.

    I am a 73 yr old male. I am interested strictly from an ED standpoint. My T level is low. I am a diabetic 2 and on cholesterol meds. Would Clomid be a consideration for my situation?

  • Bill

    I am a 73 yr old male. I have been using DHEA for 20+ years (most recently 50 mg/day) which seemed to increase my testosterone. My urologist wanted me to try Chlopmiphene. I went off DHEA for several weeks and my testosterone tested at 168. After 5 weeks of chlomiphene 25 mg every second day it went up to 368. I am still taking it but the main effect I feel is reduced libido and further reduced erectile function. I suspect T of 368 may not be good enough (I think i had higher T levels while on DHEA). I suspect either Chlomiphene 25 mg every second day may be too low or I need HCG instead of or in addition to Chlomiphene, or, if all that fails, go back to DHEA or T replacement therapy. I would appreciate any comment you can make.

  • SV

    I am a sixty-one year old male with an initial testosterone level of 530, which after two months of taking 25mg daily, jumped to 740. But my estrodial also jumped from 36 to 47. Is this a bad thing? Does this mean my estrogen went up? I am a hardcore athlete with a heart healthy diet, yet I still gained a few pound of belly fat during the last two months. Should I increase my Clomid dosage or take something to lower my estrogen? Or what? Dr. Miller: I cannot give personal medical advice here. However, generally, if one is overweight then any increase in T will also increase estrogen, which yes should be reduced. The best way to do latter is through weight loss, although an aromatase inhibitor may be used in the meantime.

  • Sidney Goldfarb md

    I am a urologist,have used cloned for 40 years for my pts. I have treated around 1000 pts. It works unless T level is under 200

    • Wow! Thank you for sharing your lengthy experience, Dr. G!

  • David W

    I am almost 5 years out from Stage one Seminoma L testicle and s/p L radical orchiectomy. T was 190 1 year after 2 dose carboplatin chemotherapy. I had all the typical symptoms of low energy, fatigue restlessness and low sex drive. PCP started depot testosterone 400 units every 2 wks with wonderful results but PCP refused to “waste time” monitoring T levels, estrogen, etc.

    Finally, oncologist pointed out that T was over 1200 at one follow-up so I cut dose in half, and eventually discontinued it all together. Now have all the original symptoms and wondering if clomid may be of benefit. My concern is I can’t find any literature about risks of clomid following germ cell tumors. Is there an elevated risk?

    By the way, I am 48, have 4 kids and had vasectomy 11 years ago so fertility is a non-issue. Just want energy, sex drive and good health.

  • Mark M

    I am diagnosed with secondary Hypogonadism and have been on Chlomid (25 mg) for for over a year. I am about to go off to see if my body continues with proper testosterone production. Wondering how long I need to be off Chlomid prior to test to make sure my body is working on it’s own. My doctor told me it would be out my system in a couple of days. Just looking for a second opinion.

    Thank you,



    I am having problem of testicular shrinkage and pain in my one of the testicals. please help me out through suggesting medicine name.

  • naeem

    i am in mid 40s. my all tests including FSH, prolactin, lipid profile are in normal range. the testosterone level is around 180. The minimum value indicated on my report is 169. the semen analysis is also normal except the motility which is slightly above normal 40 %.

    i am suffering from severe ED, PE and loss of libido. my doctor is giving me multivitamins and viagra, and is not willing to give me anything to increase my testosterone level.

    I think that once my testosterone level is increased ED and loss of libido will be gone. but he doesnt agree.

    what u suggest ? should i ask him to think about prescribing me clomid ?

    • Have him read my blog article about clomiphene citrate for secondary hypogonadism.


    I am male of 28 having primary hypogonadism & want a baby so what would you suggest please? can we take Novarel 3x ? Dr. Miller: You should see a urologist and/or fertility expert.

  • Chloe

    I am so glad I came across this article! My last two pregnancies ended in miscarriages. I checked out fine, but my husband has low testosterone. For a while he was using a cream that didn’t work, so he tried injections for months before the oncologist told him they actually lower sperm count. Here we are trying and trying to conceive again with no luck. I do have a few questions for you, if you don’t mind: Since Clomid blocks estrogen, does that affect a man’s ability to produce a daughter? I was also wondering if you could share any side effects and how long it can take before sperm count improves. Thank you for this great information!! Dr. Miller: Clomiphene doesn’t prevent men from creating daughters. Side-effects are in above article. It can take 3 months for sperm count to improve. Good luck!

  • ABC

    I am very impressed by your blog. The information on this page is very helpful. My T levels were 184 (low), while my LH (6.8 – normal) and FSH (10.8 normal). After taking Clomid 25mg for 25 days and 5 days off, my T Levels increased to 627 (normal), but it also increased my LH to 10.1, FSH to 20.7 and Estradiol to 64.3, which are considered high. What should I do? Should I discontinue Clomid? What are the side effects of high LH, FSH, and Estradiol? Should I combine Clomid with any other medicine, which may help to lower LH, FSH, Estradiol? If so, which medicine? Thanks for your help. Dr. Miller: I can’t give personal medical advice here. Please find a doctor skilled in prescribing clomiphene. That estrogen is way too high.

  • sako

    I been taking 25mg of cc for 5 days now. it seems to work only the first three days. now I feel weak again. what should you recommend my doctor to do? HCG?

  • Johnny

    I began taking Clomid to increase T and sperm count/quantity three months ago. My numbers are up, T at 800 and sperm count and quality now in the normal range. But I have developed some eye problems, the formation of several “floaters” including one very large one, I had a stye which came and went, have experienced involuntary twitching in one eye, sensitivity to sunlight, feel like my eyes are being forced into an intense stare etc. I contacted my fertility doctor and an eye doctor (the latter had never even heard of clomid, so I am not sure what use he was), and they both say there is no causal relation between my clomid usage and symptoms. I am encouraged by my numbers and want desperately to get my wife pregnant, but fear a correlation, as I have never had any eye problems in my 40 years and all of these new ones just in the few months since taking clomid. Should I see yet another doctor? Dr. Miller: Yes, you should see a different doctor. Visual changes are a known side-effect of clomiphene. HCG would be a good alternative.

  • T

    I don’t know where to begin but I will give it my best shot. I’m a 52 year old male that has suffered from depression for 20 years. Been on a variety of antidepressates and talk therapy with sub par results.It seems like my mental state has been going down hill for some time. I just don’t have the sense of well being and really could care less if I’m here or not. I recently went to the doctor for an annual physical and found my lipid levels to be out of line. Glucose fasting 123mg/dl, cholesterol 228mg/dl, trig 536mg/dl, hdl32mg/dl, ldl 113mg/dl a1c 5.5, TSH 2.04, PSA 0.3 and testosterone 191. cbc normal. My height is 5’8″ weight 177, non smoker, occassional drinker. I explaned to the doctor that I’ve had night sweats, choronic elbow problems for the paost 12 years. I’ve stopped taking advil, 4 months ago I did take hydrocone for pain. I take a multi vitamin, fish oil, gluso/chondrotin and 2000iu of vitamin d. The main concern I have is with the way I’ve been feeling. Lack of interest in life,I really have to force myself to go out, sex drive is so so and very moody. I’m just wondering if low t could be prohibiting me from leading a more fulfilling life. A few years back I became very ill. For weeks I woke up sweating so bad I had to change my clothes, sometime twice a night, fever chills, headache. Went to the doctor and was checked for lymes, came back negitive but they put me on antibotics for 21 days. I haven’t had night sweats that much since than but am very intolerate to the cold. It never seems like I can warm up. I guess in a nut shell the biggest thing I need help with is depression. I do cardio and burpees for exercises and eat pretty decent. My doctor just doesn’t seem to concerned about a 191 testosterone reading. Should I be concerned? I’m thinking of seeing an endo for advice. Your feedback is appreciated. Best regards. Dr. Miller: I am so sad reading your note. Yes, definitely low T will cause depression and a lot of your other symptoms. Yes, definitely see an endocrinologist. Proper treatment can reverse high triglycerides and diabetes too. If you are able, I can take care of you too.

  • Eddie

    I forget to say that there’s 0 sperms in a recent semen test..thanks

  • Ralph F.

    I had a doctor in Philadelphia who prescribed Clomid and vitamin D as anti aging therapy. I have since moved to Phoenix and would like to restart the Clomid. I assume this is a prescription drug, can you recommend anyone in Phoenix who is aware of this therapy whom I could go to?

    Dr. Miller: Hi, Ralph, I don’t know anyone in Arizona who prescribes Clomid. I do see patients from out of town if you are willing to make the trip.

  • raj s.

    I had a problem with erectile disfunction and low sexual drive,so can clomid cure my this problem??? Dr. Miller: Depends on the cause.

  • Linny P

    I had low T and got androgel. I got PCV quite bad so came off. Took a long break now I am back trying to get my own T back using clomid 25 mg qd. I also take arimidex 2mg q week. My results after 4 months of therapy are my T went from 197 to 298, my E2 went from 28 to

  • J. Lee

    I had my doctor prescribe CC to me and have been taking it three times per week for two months. My levels are back in the normal range and my free testosterone has come down to normal levels. The only problem I am having is weight gain. My body fat percentage has steadily increased since I started taking Clomid. My caloric intake has actually lessened as a result of this, but I still continue to gain weight. I have had to stop taking CC as a result. Is this a side effect of taking Clomid and if so, what can be done about it?

  • Mark S.

    I had RP surgery 13 years ago where my prostate and seminal vesicles were removed. I was diagnosed with low T and I have been on testosterone therapy for about 5 years. Since this time my testicles have shrunk to almost nothing. Can Clomid work for me even though I have no plumbing in place to deliver the sperm?

  • Wineman

    I had the same problem I’ve heard mentioned by several people above. Was using testosterone therapy for a few years and when my wife and I wanted to have children I had a zero sperm count. I was stopped the T treatments, prescribed clomid, and had my wife pregnant within 6 months with a “Normal” sperm count.

  • esm

    I have low t, fsh and lh due to testosterone use. I have been put on a course of novaldex and there has been no change in levels for 6 weeks. Does this mean I have shut down or continued use will turn this around?

  • Henry

    I have a low sperm count & would like to have children. My partner & I have been trying for 18 months. Will clomid help with with getting a stronger sperm count & where can I get it from. Dr. Miller: Yes, it can, and you can try going to your urologist or endocrinologist.

  • crew

    I have above normal range SHBG (70 compared to range of 10 – 57). As a result, I have low Free T (7 compared to range of 9 – 55). From what I’ve read, it appears Clomid raises SHBG. Should I assume that Clomid would compound my problem of already high SHBG? Thank you. Dr. Miller: Not necessarily. I haven’t seen that with clomiphene.

  • Mark Ambundo

    I have azoospermia. Can clomid be beneficial to me?

  • k

    i have been diagnosed with low T when i was 27. now i am 32.still the levels are same. i don’t know what is the real cause. there is no problem with pituitary gland. could it be primary hypogonadism then? then will taking clomiphene help? Dr. Miller: You need to find a doctor who can help you. Clomiphene doesn’t help primary hypogonadism.

  • Brian

    I have been married for two years without child, I went for semen test and discovered I have low sperm count, for the past one year I have been on speman, vit e, zeeman, I noticed little improvement my sperm count rose from 1% to 10%, doctor can combination of drugs listed above with clomid be of help. Please we need child seriously.

  • Johnny1965

    I have been on 25mg Clomid Monday Wednesday Friday for 15 months now. My test was 270 before start, then after 3 months >900 six months later at 600 and now at 470. Should I stop for a while and restart. Is there something like Optimum cycles and if yes, how qould You recommend to cycle CC? Thank You for your response

  • Rob

    I have been on 50 mg of Clomid for more than a year (I am a 54 year old man). Now, my cortisol, LH and FSH is over the roof. T-count is up to around 453, but these doctors don’t understand the use of Clomid or the dosage. Not sure what else to do…had T-shots for about 8 months prior, but too many typical complications that I didn’t like. Now I am going for a brain MRI to see if the tiny posterior pituitary nodule has grown. I think I just want to get off the clomid and deal with the lethargy…since I still have this. Any suggestions?

  • Jason

    I have been on clomid 50mg every other day for about 100 days now and have had great success despite empty cella and slightly elevated prolactin. My T levels have improved greatly and the only down side is slightly elevated estradiol. It took me years and many other treatment methods that made the situation worse to talk a doctor into giving me clomid. Now my challenge is trying to talk this doctor into giving me Armidex in order to combat the elevated estrogen. Do you think Armidex would help? Dr. Miller: I’m sorry you have had such trouble finding good care. Yes, Arimidex is an aromatase inhibitor which can prevent the conversion of testosterone to estrogen. However, many times just losing weight can help since the aromatase enzyme is mostly found in fat cells.

  • Ray G

    I have been on clomid for two weeks. The first day I took it, 4 hour later I felt 18 again, but the second day I din not feel anything great . Clomid has also given me a ringing in my ears. I am considering to DC this medication.

  • Mark

    I have been on clomiphene (fertomid) for about a month. I am diabestes type 2. During the last 3 weeks my sugar levels have been raised, and I have a slight blurriness in the eyes. I am now on a diet to see whats cauisnf the problem. Can clomiphene cause such problems? Dr. Miller: Yes, clomiphene can cause visual disturbances. Have not heard of it causing diabetes.

  • CHRIS W.

    I have been on Clomiphene Citrate for 4 weeks, and recently had my Testosterone levels checked again. They started out at 194 and with in 2 weeks of taking 25mg per day they have increased to 271. I was wanting to know when will it level off? Dr. Miller: 6-8 weeks.

  • Aman

    I have been on hcg for 2 months so far, with only a small increase in t. Can you take Clomid at the same time as hcg injections or will I have to stop? Can you give approx timescales in which men see increased t levels on Clomid?

  • Bubba

    I have been on Trt and hcg for over a year now along with letro but it has been hard to keep my hormones balance as when my estrogen is high I get dark pigment spots that look like Sun spots so I would like to stop Trt and try clomid will this work and how do you transition? Thanks

  • Manish Kumar Patel

    I have been planning for child since last one year but could not get it, I have gone through siemen analysis, count is 80 millions but motility is 50% only. Dr. Has prescribd me Clomiphene citrate 25 mg. Would it help for increasing motility? My wife’s reports are all normal. Kindly reply as soon as posssible.


  • Alger

    i have been taking clomid 50/day for about a month. fixed ED problems and a few other problems i was having, fairly quickly, went from T level of 202 to 560. when i was about 25 i started noticing changes in my genitalia (penis shrink, testicles didn’t hang as low) and went to doctors who said nothing was wrong. now at 40 i have been prescribed clomid. the prescribing doctor said over time my levels were probably dropping until they just got so low other symptoms manifested. the prescribing doctor had an mri (4-5mm microadenoma) and testicle ultrasound (one was 4cm, the other 5cm). i noticed when my t levels were about 500 my genitalia starting going back what it used to be. when the doctor tried lowering clomid to 25/mg i started noticing many problems, including the shrinkage again. the doctor wondered if i had taken steroids at any time. i did not. sometimes, especially when exerting myself such as exercising, i notice everything shrinks a lot. i was told in time clomid may fix these problems too. have you seen cases whereby clomid fixed these problems? if not what have you seen cause these problems.

  • Barefoot Kowboy

    I have been taking Test years. Four years ago my wife and I wanted to have a baby and my Endo MD prescribed an injectable drug called Novarel 3x a week. I had a zero sperm count (less than 1%). After a month of shots we were pregnant! This was after my urologist told me it was impossible to bring back my sperm count due to the length of time I had been on testosterone.

  • cleve

    I have been taking this for three months and the only effect I have seen is a tremendous weight gain. I have put on about 35 pounds during this period. I must say also that I had prostate cancer and took radiation and kemo. should I continue to take this or is there and alternative? Dr. Miller: You need to discuss with your doctor, yes there are other alternatives.

  • Dr. B from Canada

    I have been using Clomid for a few of my low Testosterone men for the last few years. I am finding that I only need to use a small dose for most, 12.5 twice or even once a week. I can stop and some will have normal T levels for 6 months or longer. Has this

    been your experience? Also what is your feeling on Androxal (not available in Canada yet)? Dr. Miller: Yes, I generally recommend using lowest effective dose. If primary cause of secondary hypogonadism is reversed, then yes sometimes only short-term treatment is necessary. I prefer using drugs with longer safety history.

  • sanjay baral

    i have diagnosed that i have only 2 percent sperm motility.. i m 26 yr old.. can this be cure? i m very afraid help me suggest me plzz

  • Greg H

    I have for the past 2 years had very low T 135 to 145. Even losing 110 pounds hasn’t made any difference. I have no energy, ED, etc etc. Diabetic, heart patient. My weight loss has fixed most of that except for the energy and ED. However, my endicrinologist started me on AndroGel for 3-4 months i felt like a rock star with 795 levels. The fear of using hormone replacement therapy is the need for having to do it forever especially if it isn’t necessary. So we tried HRT for a short period and it worked. Then we removed the HRT for the same period to see if my body would have woken up. It didn’t. my levels are 250 to 312 and i am 46. My Doc offered one more suggestion in taking Clomid before heading down the path of permanently needing HRT. I completely and fully trust my DOC but i was leery of another delay. I am tired of feeling exhausted, the ED, memory loss, lack of focus but if this can help I was willing to give it a shot. I will start taking today. I appreciate your article which helps support what my DOC is asking me to trying to do for me.

  • JCarson

    I have had both testicles removed due to cancer and can no longer afford androderm or other creams. My T level is close to nothing and looking for alternative. I am 49.

    Dr. Miller: Clomiphene would not work in this situation. Injectable testosterone may be cheaper than a cream. Or compounded testosterone cream through a compounding pharmacy is much cheaper than brand names.

  • Don

    I have had issues with T crèmes causing an increase/converting to Estrogen. Will Clomid cause an increase in Estrogen?

  • Brian

    I have had low t for a few years now, I’m 36. I’ve tried the shots and didn’t seem to work and gained way to much water weight, 10-15 pounds. Would clomid be something to try?

  • Anees Ahmed

    I have just started CC treatment and my physician has recommended 5 days break after every 25 days.Please suggest me should I take 5 days break or continue for three months. If break is necessary please give me reference of the clinical trial. I would appreciate your early respose.

  • Douglas

    I have lost my Libido after being on a topical test for 3.5 years using 175mg, 1 gram twice daily to switching over to 5MG of clomid 5 days on 2 days off… Is this normal? I have been on the Clomid now for 2 month and I have loss of appetite, loss of libido and afternoon tiredness… Total and Free T are up but it doesn’t seem worth the trade off…

  • Shaik

    I have low sperm count and dr. Advise me to takr clomid for 3months. Will it help

  • m

    I have low t dr but clomid two month lost lot weitht is good to lost weitht please halpy

  • Walt J

    I have noticed blurred vision and could not attribute to anything till I read that it could be the Clomid, right? I have one other concern, however; there seems to be a lump about the size of a normal testical in the area where testicals can rest up in the body, the other 2 testicals are normal. Any idea? Dr. Miller: Yes, in general, clomiphene can cause blurry vision and one would need to see an eye doctor as soon as possible. Also, mass in testicles needs to be evaluated by a urologist. It could be anything from a tumor to a hernia.

  • holyhead

    I have post finasteride syndrome after stopping propecia..I have gained 30lbs in 7 months and haven’t changed anything else..I was told this drug could help..No one wants to listen about this.

  • tom

    I have really bad sleep apnea and am pretty thin. I have heard that lowering T levels can be a cause of apnea but T therapy can make it worse. This makes me hopeful that it might help . Ever heard of anything like that?

  • Jason

    I have secondary hypogonadism due to empty sella syndrome. I have slightly elevated prolactin, low lh and low fsh, and extremely low t. I also have graves disease and underwent RAI. I started clomid 50mg every other day about 3 weeks ago. Is it normal to feel more tired now and depressed? Is it possibly because it is making my testosterone convert to estrogen? Dr. Miller: I don’t think clomiphene would work if one doesn’t have pituitary. HCG would be a better choice.

  • Gregory

    I have stoped testosterone therapy 4 months ago because I was loosing hair including hair transplants. I am have been on Clomin for three weeks. Libido still has not returned. I am getting hair on my chest, my testicles as big again. But it seems that I may still be loosing hair. I have been on Propecial for 12 years. Could Clomin be the cause of my hair loss.

  • Rakul

    I have suffered severe sideeffcts after using finasteride for treating hairloss. My T levels fell down to 169. Can clomid help in this case. Have u seen any patient getting recovered from side effects of finasteride. Please advice. I am totally confused abt how to get back to normal.

  • Hasledalen

    I have taken myself off clomid. I have been having strange brain issues, almost like an electrical shock. Only lasts.a second but scares the heck out of me. Could this be due to the discontinuation of clomiphene citrate?

  • worried

    i have venous leak and low t. will increasing my t will fix the venous leak to some extent? Dr. Miller: Sorry I don’t know the answer to this. However, high estrogen levels (which are common in men with low T) can cause venous insufficiency in general.

  • David

    I just had my T tested, came back as 243. My doc says it isn’t low enough for drugs yet. She suggests I workout more, however I currently workout 4 hours a week. I don’t have the energy to workout more and have to really push myself to maintain this routine. I have difficulties maintaining an erection and am losing interest in having sex. Help! Dr. Miller: WOW, this is such sad advice! Come see me. Email me.

  • jammin

    I just started taking this, and i feel way better. but i my face is crazy oily like i was 13 again. normal? and how does it affect metabolism? Dr. Miller: Yes, an increase in testosterone can increase oil production.

  • Trooper

    I just took the exact meds you are talking about I took the fotuislrlm starting in the beg of Oct and then the trigger shot I took last tue at 2am! I had the IUI last Thursday afternoon and just started the progesterone suppositories last night.They started me on an injection of 100 and then took it down to 50 for 2 days then up to 150 for the last 3 days. They are very careful not to give too much or too little so they took blood and did an ultrasound every 3rd day while I was on the meds. The fotuislrlm injections were real easy and I didnt feel any different while on them. The trigger shot is a bit more involved and my hubby did that since its in the butt and intramuscular. Ovulating felt the same as normal except I felt real, real, real heavy in my tummy for 2 days after the IUI and had a bad case of diarrhea but I don’t know if that is from the IUI or just a fluke.Anyway, im not trying to be a know-it-all but these are just all the questions I had before I went so I figured I would fill you in on my experience. Wish I could tell you it worked but I wont know til the 16th of this month. I am trying to stay hopeful but all that I have read and heard there is suck a small chance that it could happen with the first one .. the 16th seems soooooo far away! Good luck to you, hope it works for you the first time!!!If your hubby has a good sperm count and motility then your chances are better oh, AND also you will have a lot of the pregnancy symptoms after the hCG injection (the trigger shot) because that is the same thing your body produces when you are pregnant. So you may have sore boobs, heavy stomach, a diversion to some foods, etc. Just thought I would let you know cuz I thought I was pregnant 3-4 days after the IUI so I took a test well it was obviously positive cuz thathCG is what the pregnancy tests look for. It was a just left-over from the hCG injection.

  • D

    I read your blog about clomid and i was hoping you could answer a couple of questions. Specifically, i have been diagnosed with metabolic syndrome, i take metformin, my T levels were around 250, and my Endo inidcated that it shouldnt be low as my testicels are actually quite large. Does this sound like a situation in which Clomid might be effective? More to the point, how does clomid interact with diabetes? Dr. Miller: Yes, clomiphene may help. Diabetes can cause secondary hypogonadism, through hypothalamus probably.

  • P

    I read your blog and wanted to ask you a question that has been bothering me… I took a steroid cycle and used Clomid (generic from Cipla) to restart my HPTA. I have noticed a sudden onset of eye “floaters”. Lots of white and some black dots in my vision, big, small, etc.

    would you be concerned if I was your patient? I know floaters in general are not normally a sign of anything serious, but because of my situation I want to make sure it isn’t a sign of a tumor or something serious.

    I plan on continuing Clomid at 50mg for another month or until my blood results show upper normal T.

    Thanks, I appreciate your response. Dr. Miller: Yes, I would go see your eye doctor and doctor who prescribed Clomid about this matter.

  • Caleb

    I recently got my test level checked and all my hormone levels checked. Everything came back normal except my prolactin level which was a 3.5 and my testosterone level which was a 46. I’m an 18 year old male and can’t get an erection. Have low sex drive, depression, constant anxiety, all symptoms what seem to be from low t. I’m honestly sick of dealing with the issue. And 18 year old male should not have these problems at all. I admit to taking 2 cycles of prohormones. I didn’t post cycle like an idiot. But I’m on 20mg of clomid for 4 weeks. Do you think this will help me at all? I need and answer and iM sick of feeling like this

  • Taiwo

    I saw a urologist 2 months ago who recommended a varicocele removal surgery. A scan also stated that my left testicle was not as functional as the other. Can taking clomid reverse the condition and boost my sperm count as i have not had a baby yet with my wife? Dr. Miller: I don’t think Clomid can overcome anatomical problems in the testes, but I am also not sure that a varicocele would interfere with sperm production.

  • Peter

    I started clomid at 50mg / day and within 30 days my T level went from 158 – 1348. I feel great in the GYM and really feel like I am gaining muscle. The only notable impact was I initially had strange anxiety feelings. I found that if I worked out harder they would go away. (it could have been just the surge of the added T-Level). I don’t know how long I can stay on at this level but I am not wasting a second and hitting the gym 5-6 days a week.

  • Frank

    I started taking clomid 6 months ago – and I am beside myself with how well it has worked for me. I’ve put on at least 10 pounds of muscle, I feel great, I’m smarter, better mood and temper, and, well… I’m young again. It’s certainly worth a try, given its safety and low cost.

  • Finan khan

    I think it “Clomid” may be used after a dianabol consuption by body builders to restore the T levels to normal values.


    I took clomiphene for only one week. Cause I started feeling head pressure, but I felt strong in the head as well. I stopped the it, and now I sleep better..I still feel strong, and after an orgazim I feel strong right away with out my usual 10 days of depression. Dr. Is it possible that shirt duration on Clomid kicked started my brain into producing Testosterone…and could this effect now be permanent.

  • Jason

    I took finasteride (1mg a day) for almost two years and it completely destroyed my testosterone. My research shows that there is a legitimate medical condition called “post finasteride syndrome” May 24th of this year I started taking TRT injections. On May 24th I was actually at 200 Nanogram/dL and my July 27th levels were 154 Nanogram/dL. Doing TRT actually dropped my testosterone levels. I was on it for two months and tested every month and it went from 200 to 154 to 134 on August 07, 2014. From there I found out about clomid and I started taking 25mg once a day and within a month it raised my fsh and lh levels, which had been very low before. On August 07,2014 my FSH was 0.3 miu/ml, LH was 0.5 miu/ml. September 5th testosterone increased and was 242 Nanogram/dL, FSH was 10.0 miu/ml, LH was 9.9 miu/ml. October 9th Testosterone maintained at 264 Nanogram/dL, FSH 10.0 miu/ml, LH was 9.9 miu/ml. Again for the record I started taking clomid after my September 7th blood test. On November my tests showed testosterone at 260 Nanogram/dL, LH was 7.7 miu/ml, FSH was 10.1 miu/ml.

    From these tests it shows high gonadotropins of FSH and LH that should be sending signals to my testes to produce testosterone but it clearly is not doing this. It is almost like finasteride gummed up my testosterone receptors. I am alway tired “as hell” (forgive the expletive) I play basketball 3 to 5 times a week and lift at least two times a week. I don’t eat sugar or wheat and it helps a lot but nothing is a good substitute for not having testosterone.

    Since November I started taking 50mg of clomid every day spaced out (1 25mg tablet twice a day). I just went in this morning to get a blood test and have not received the results yet. One thing that is unique to me is that I have been sleeping really well for the first time in more than 2 years but just since I took 25mg of clomid. I am not sure what to do or if there is something else that I should or should not be doing. I do not want to be on TRT the rest of my life and would deeply appreciate knowing what you think I should do. Thank you.

  • Paul

    I took propecia (finasteride) for hair loss, 5 months ago and since this time I have been unable to achieve an erection, my low T level was last checked at 6.9 nmol and LH was 1.4 iu/l and 2.7 iu/l

    Do you think clomid could help restart my hormone system again and get my T levels functioning normally?

    How long do you normally recommend going on clomid for and how much?

    Thank you in advance. Dr. Miller: Yes, propecia can do that. Clomid may work. I’m sorry but I can’t give personal medicine advice here.

  • Dan

    I tried test. gel for 9 months and it did not work. However, I tried Clomid 50mg ED and it worked well for 4 months but is not working suddenly. I’m looking for options when Clomid stops working. I can’t find any studies in journals that detail what to do when Clomid stops working. Thanks. Dr. Miller: If it isn’t working then you may have primary hypogonadism and you would need to try testosterone again, maybe injectable T would work for you. Good luck.

  • Kevin

    I understand that Clomid works in men with secondary hypogonadism by essentially lowering estrogen production. My estrogen is already in the low normal range. Dr. Miller: It doesn’t lower estrogen, more like blocks the estrogen receptor.

  • Lee

    I want to thank you so much for the information here! I am 26 and have been suffering from extreme fatigue, foggy memory, no drive, mood swings… the list goes on. I went to my family Dr. here in WV and he had blood work done on me and found out that my T was 234ng/dL in March 2013 and has slowly gone down since then. He sent me to an endocrinologist that wanted to put me on antidepressants… then to another that said nothing was wrong with me. He was very frustrated and took it on himself to find out what was wrong with me so he issued a MRI on my pituitary gland, ultrasounds on my testicles, sleep tests, and more blood work. Everything came back normal except on the thorough blood work he noticed my LH and FSH being low at 1.8MiU/mL for LH and 1.6mIU/mL for FSH. He wanted to put me on AndroGel, but not only does my insurance not cover it, I eventually would like to have a kid so $200 every month for the rest of my life is out of the question. I tried bringing up Clomid to him and he was very adamant about it saying that it was not for me. So now… after all this time I continue to get worse and worry about losing my job and life to something I cannot control because I can barely function as a person. I have looked into a few doctors here in the state, but this state is not known for good healthcare and it makes it very difficult to find a doctor that will prescribe Clomid because they are so behind in the times. Do you have any suggestions on what I should do? Thank you for any feedback! It is extremely appreciated. Dr. Miller: I believe Dr. Warren Levin prescribes Clomiphene and his location is closer to you. Otherwise, I would be happy to see you.

  • Brian

    I was diagnosed with low T & on testosterone for two years. I came across this article & told my urologist I wanted to try clomid. Took clomid 50 mg daily for two months & got my levels checked & everything was great & I felt great. Dr. Advised to stay on for another three months. Recently I started to lose my libido. I will soon have a dr appointment & get blood work done. My question, if my estrogen levels are high & I backed down to 25mg daily, would that reduce my estrogen levels?

  • Bobby V

    I was given Clomiphene for low T. It seemed to help with my symptoms. However, after 3 weeks of 25 mg ED, I experienced strange visual symptoms – not just blurring, but it’s like streaks were imprinted across my vision when I would look at lights, and the impression of streaks would remain for a long time afterwards.

    I discontinued Clomiphine, and these symptoms have resolved. However, low T seems to have now returned.

    I read that Nolvadex performs much of the same functions that Clomid does, but without these visual side effects. Rather than getting HCG, do you recommend trying this first? Thanks.

  • Juan M

    I weight 200lbs and currently dieting. Will clomid be ok to take and not convert lots of estrogen? Dr. Miller: You have to discuss with your doctor. And yes, it can convert to estrogen if one is overweight.

  • David

    I wish more endocrinologist knew this, I am 28 and was put on Androgel for Low T about the years ago. I am a type 1 Diabetic with serve chronic nerve pain (been to the best clinics around the states and tried everything in wholistic medicine most people have heard of. I understand that using pain medication contributes to the Low T along with diabetes. My wife and I were starting to plan on having a family when my family doc informed me three was a new endocrinologist in town so I could stop driving to Denver to have my diabetes managed. When I was put on the Androgel I was told I would become sterile if I didn’t start the testosterone replacement therapy. Turns out it actually makes that problem so much worse?! I started on the clomiphene today thanks to my new, more knowledgeable doctor. I found this site researching side effects. Changes in appearance have been mentioned but not in any detail that I can find. Can you explain this in more detail? Chance of enlarged breast, voice pitch, muscle mass, etc? Dr. Miller: Chances of increasing testosterone too high with clomiphene is rare. However, testosterone does convert to estrogen, so if one has high body fat he would need to lose weight to avoid this. Or take an aromatase inhibitor.

  • Casey

    I`m very interested in your product. I was a pro bodybuilder for many years and now suffer from low T. Any help will be welcomed. Dr. Miller: Hi Casey, If you are interested in becoming a patient, please email me.

  • Tijo

    I’am 35 yo my free T 55.6 total T 285 I start Ob clomiphen 50 mg daily, do I have to take clomifen for life or only for 6 months

  • jas

    iam 35y age and have a problem of dalay puberty I have very low testorone level now stated pregnyle1500 but during this treatment I feel premature errection just after putting. I want to ask what is its side effect and how it can be prevented. Your response will be very helpful in this tense condition. THANKS

  • Richard

    If I overdose on clomid what are the side effects??

  • Barbara

    If low test is coming from a 4mm pituitary tumor, is surgery recommended? Patient has just started clomid. Dr. Miller: Decision to go to surgery depends on benign vs. malignant status and response to medical management.

  • Jay V

    If the clomid does work your test levels will rise but wouldn’t your estrogen level also rise significantly as well? Could this lead to all the side effects associated with high estrogen in men? Are other drugs like nolvadex used together with clomid to conteract the estrogen? Dr. Miller: High estrogen doesn’t always occur, really only when man is overweight or using too much. Optimal weight should always be obtained, or use aromatase inhibitor in the least.

  • Shafique Ahmed

    if work good but need more clical trial on man. I am one of the candidate…thank you so much..

  • Peter Kramer, Ph. D.

    If you were to mention that 25 mg/da is the typical starting dose, that would be informational, not prescriptive. Incidentally, one of my best friends is a world famous HCG expert, Larry Cole.

  • david

    im 28 and have little facial hair

    all family men have very full beards. ihave foliculs too

    i used finasteride for 11 yeaas

    my testosterone is 4.1(3-9ref)

    dht 650 (250-990 ref)

    e2 55( men under 55 ref)

    tsh lh fsh t3 t4 d3 prolactin dhea and all hormones are fine but lh fsh are low normal range

    i have 17 vial hcg 5000iu

    and alot of clomid and letrozol

    with one is better?

    hcg+ letrozol or clomiphen?

    if hcg 250 iu 2-3x /week is enough?and can i use compounding hcg(powder with inject water) in refrigerator to use it for 1 month?and if clomid is better 12.5 mg 3x aweek is good and how long is it safe? Dr. Miller: I’m sorry but I cannot give personal medical advice here.

  • Eddie

    I’m 29 years old, I got puberty naturally but after one year I didn’t have any semen ,blood test said that I have a low T ,LH and FSH .MIR scan

    for pituitary gland clarify that it’s smaller than normal and , I used Testosterone injections for 9 years ,currently I’m using HCG 5000 iu once a week and the T level is normal and sooner I’ll add HMG 75iu thrik a week to HCG…do you think that I can use Clomiphene instead of them as it raises the T level and sperms count?

    thanks a lot for your help

  • M Shalakany

    I’m 40 old in the past I wasn’t have primary problem the T level was just normal but FSH is low and normal LH these condition affect the sperm production I tried many treatment and many testier biobecy leat to a problems in my testis and became small

    Last year T was under 1 ( Norma 2.42) i injected with HCG it increased to 2.2

    After that I make an MSA for ICSI

    T become very low (0.2) I start HCG and andractim but it is still .65

    Can Colima 50 help to increas the T

  • JZeb

    I’m 49. I’ve had several traumatic brain injury incidents and there is damage to the pituitary gland. The first finding was my Testosterone was very low and I was prescribed Clomid. Additionally its been determined I have very low HGH and have been prescribed Somatropin. I can find no medical information with regard to using the two drugs at the same time. I take 50mg tablet of Clomid every other day and a .4 of the Somatropin every day. Any thoughts on this combination?

  • NoLimit

    I’m a 25 year old male and my testosterone levels initially came back at 287 after testing at 9AM in the morning. I was feeling depressed/stressed at work and heavily fatigued as my job required me to work 10-14 hours a day. My doctore recommended clomid as this would not affect my body’s ability to produce testosterone naturally if I discontinued treatment. 8 weeks after starting clomiphene at 25mg per day my testosterone levels increased to 1079! This test was administered at 6PM therefore theoretically my levels would have been higher had I tested in the morning. I have noticed a tremendous enhancement in my mood, productivity at work, and energy levels. My energy/drive at the gym has greatly increased as I have noticed I am less fatigued throughout my workout. I have discontinued taking a pre-workout supplements as that was previously essential to me even making it to the gym. I’m 6’6 and my weight has remained consistent at 225 but I have noticed a considerable reduction in body fat around my waist as well as greater muscle definition and mass. I have more energy now than I did in high school. It’s truly remarkable!

  • Bob E

    I’m am a 23 years old male. My t levels are around 250. I was prescribed Clominophene 50mg 3 times a week. I have had trouble lossing weight since I can remember. Would it be realistic to expect to lose fat while taking this medication (supplemented by a healthy diet, which I have)?

  • kanel

    Im considering to take Clomid 25mg for raising testosterone. Before I start I would very happy if you could answer these questions. Whats the best time to take Clomid (before sleep or in the morning or immediatly after waking up)? and should it be taken on an empty stomach or full stomach (before or after meal)? Information from the doctor is much appreciated.

  • Stan

    I’m just starting on 25mg / day of clomid, but was not told what time of day is best, or if it should be taken with or without food???

  • Greg

    In September 2012, my total T level was 125, and that was while I was on T injections. In October my Dr put me on Clomid (50mg) and as of March 2013, my total T level is 831. That is a 706 point increase in 6 months. What a difference clomid has made in my life…I feel like a new man! Why do you think you see so many low T commercials on TV now days…they know low T is a problem in older men and they want to sell you their product which makes them millions and once you are on the cream or injections, they have got you and you have to keep using it just to feel normal.Find a Dr that thinks outside the box and does not care about making the drug companies richer like I did.

  • Go

    In the article, what do you mean by ‘visual changes may occur’? Thanks

  • Russ

    Is an AI necessary when using Clomid?

  • John

    Is clomid effective for men with low testosterone due to long term use of opiate pain medication for chronic pain?

  • Angela

    Is it possible for Clomid and hcg usage in men to affect women thru bodily fluids. I have POS and my husband takes Clomid and hcg for hypogonads secondary to bodybuilding. My POS has become worse and my prolactin levels have increased. Could this be secondary to intimate activity. My Gyn isn’t sure 110% if Clomid and hcg can’t be found in semen. Appreciate your help. Dr. Miller: Interesting question, I wouldn’t think it would be significant, but sorry don’t know the answer. Consider an endocrinologist, read about diet and PCOS.

  • Zack

    Is it recommended to take Proviron 25mg/Day with Clomid 25mg/Day? Taking Proviron Only for the first 8 Weeks?

  • Mahmod

    Is it right to allow kids to carry intolerable amntuos of weight in their backpacks?In this economy, many schools have begun to cut back costs and programs and that often includes slashing class set textbooks.The result is this you have a 11-year-old (give or take a few years) of small stature who walks 1 mile (or 2) to school, common scenario.The weight he has to carry quite often unthinkable, especially in schools that can’t afford lockers. In perspective, many adults would have trouble lifting even lifting many of the bags young children carry, not to mention maintaining upright with it on for prolonged periods of time AND NOT TO MENTION trudging 1+ mile with it.And the small kid lugs that thing around, sore necks, sore back, it probably takes it all their body’s effort to remain upright, not fall over, ignore the pain, and keep taking the next step Many couldn’t bare a minute holding up one of those bags filled with 7+ pound textbooks, let alone walking 1+ miles with no breaks.So what do you think is it wrong to have young childrens’ books and bags excruciatingly heavy, so much that many would have trouble even moving it 10 feet?

  • Joseph AG

    Is it true that Clomid used by men can cause hair loss? If yes, how common is it? Finally, is it reversible if you stop taking it?


    Is T level of 350 is considered on a lower side for a male of 42 years I am suffering from Low sex drive

  • N

    Is there any possible connection between taking clomiphene and developing insomnia? I started taking clomiphene last July, and the first 2/3 weeks I was on it, I felt amazing: more libido, more energy, gaining muscle, stronger, etc. After a couple weeks I started developing severe insomnia that hasn’t gone away since then. I’ve continued taking 25mg every night, but I’m starting to wonder if taking it in the morning would be better for my sleep. Do you have your patients take it at a certain time of day or does it not really matter? Dr. Miller: I haven’t had insomnia side-effect in my patients taking clomiphene, however it may have to do with your dose, and your testosterone or estradiol level. Or, the cause of your secondary hypogonadism in the first place. Please consult with your physician.

  • Neil s

    I’ve been on and off steroids for years and now suffer from depression and nervous anxiety, could clomid help me? Dr. Miller: Yes, if low T is the cause.

  • Ben David

    I’ve been on Androgel pump for two and one half years. I started out with 200 total testosterone and with 60 mg of product got level to 800 (with 40 mg got to an unsatisfactory 500). One year ago I stopped Androgel and testosterone dropped to 45. I then begin 50 mg Clomid and in 45 days level increased to 245, which was unacceptable. I stopped Clomid and went back to Gel. Did I stop too soon? Any reason to believe another couple of months would have brought total testosterone to acceptable levels? I’m healthy 66 year with good muscle mass and sex drive because of Androgel, but really don’t want to use it the rest of my life, if Clomid can work. Is it reasonable to think Clomid is still a possibility? My initial diagnosis was secondary hypogonadism.

  • Lew

    I’ve been on Clomid for about 6 months now. Wish I had known about this stuff earlier. I was on T injections before. It worked just ok with highs just after I injected and lows as it wore off. After I started to develop man boobs I asked the doctor about other alternatives.

    He talked to me about Clomid and after a little research I tried it. Had to take the injections for another 2 weeks because Clomid takes about a month to kick in. Once it kicked in I really balanced out. My energy level picked up and I got my motivation back.

    I have told my doctor to prescribe this as a first treatment rather than T shots. It works great and its not expensive at all -$15 with insurance, $45 without. If you’re considering Clomid try it for about a month. It works.

  • Ron C.

    I’ve been on some kind of Test replacement therapy for 10 years now. That was before all the hype and commercials ladies. The thing is your body adapts to the dosage and you have to increase it over time. That’s why the gels and patches quit working for me. Dr. Miller: Thanks for your comment. Clomiphene or HCG still may work even though you have been on T for some many years, depends on cause of low T in the first place.

  • lester

    I’ve been suffering from depression for 20 years and it the past 3 to 4 years it’s gotten worse. Been on ever kind of anti depression drug out there. I went in for a physical about a month ago and found my lipid levels were out of whack. My current doctor of 15 years said he could do nothing more for my depression. So, I decided to see another doctor. I went over my medical history with him and was very candid about my struggles with depression. He immediately ordered a thyroid test, PSA, A1c and wanted to check my testosterone levels. Everything was in order except my testosterone. My reading came in at 191. I’m not sure what my free t was or shbg levels are. I was told that my levels were barely low and not to worry about it. I don’t agree with him at all. Is this number low for a 52 year old male? If I can start feeling better by raising my t levels to me that would be priceless. Unless you have suffered from depression you can’t imagine what it’s like. It has such a negative affect on every aspect of your like. I’m not looking to be twenty again I’m looking for help with depression. All I know is I don’t feel very good mentally and what I’ve been doing in the past is not working for me anymore. I’m 52, take pretty good care of myself and won’t just accepted this is the way life is going to be for me. I’m thankful for people sharing there view points on low t. If I can nip this depression I think everything else will fall into place. Your feedback is appreciated. Take care! Dr. Miller: That is definitely low T and low T can cause severe depression, and increasing testosterone levels-using clomiphene, HCG, or testosterone (depending on cause) can definitely help. Sorry you have suffered so much!

  • Friendly Friend

    I’ve been taking 25-75mg of chlomid for three weeks and my testicles have become pretty solid and hard to the touch. Is that just increased sperm production? Is it something I should be concerned about?

  • Frank

    I’ve had low testosterone for over 10 years, and have been on Androderm, Androgel, and now Fortesta. My level without testosterone was about 190, and with the testosterone moves up to about 350-450. My testicles appear to have shrunk and my new urologist commented that they were small and this might be due to taking testosterone supplements. Could a Clomid approach instead of artificial testosterone restore the size of my testicles and increase my testosterone to normal? To restart my testicles to working, would I need any other drug beside Clomid? Dr. Miller: If one has secondary hypogonadism, then yes it’s a good alternative to testosterone, and usually only clomiphene would be needed.

  • ken

    Just got off of androgel, it was impossible in my city to find a doctor to get me onto Clomiphine citrate, I suffered a massive concussion at 13 I never lost my chest fat had delayesd puberty and was smaller than my family and yet doctor after doctor dismiised my concerns stating I would develop until 20 to 21 there was always time of course the time for a blood test would have been minimal to the time spent in morbid depression as a teen and young adult. If you have a child who is active in sports or cycles and gets a concussion please take your child in and have a blood test done to ensure his hypothalamus or pituitary were not affected and his levels are normal for an adolescent. Thank you Dr Miller and Dr. Mark L Gordan Clomid blocks the receptors that convert free test to estrodial as well.

  • Mike

    Just wanted to post my experiences here. I am a 30 year old male, very much in shape, but diagnosed with depression late last year. Decided to get my testosterone levels checked and my T levels were low, in the low 300s. That seemed low for someone who didn’t have any health issues, was not overweight and was very active, workout out religiously, eating very healthy, and playing sports. My primary care doc wanted to put me on a gel, but my sister who is a physician recommended that I see an endo. The endo put me on clomid 25mg daily. My T levels went from the low 300s to nearly 1100 in 1 month! I’ve also lost 10 lbs and gained tremendous muscle definition. My estrogen levels have increased to the 40s, so we are pulling back to 25 mg 3x daily. My mood and energy levels have never been better. This has been a real life saver for me. I just hope the effects will be permanent once I eventually ween off of the drug.

  • Brian Russell

    just went for my annual physical exam last week, when the doctor examined my testicles he said that my left testicle seems to be very very small and very soft and doesnt feel like it is in the best condition, have had aches in both testicles but more so the left and takes a long time to ejaculate. he did some blood tests and found my total testosterone is 237. I am 44 years old. he wants to reexamine my testicles and prostate and start some kind of testosterone replacement. is clomid worth asking about?


    KINDLY LET ME KNOW THE DOSAGE. THANK YOU. Dr. Miller: I’m sorry but I cannot give personal medical advice here.

  • Morgan

    l have been experiencing this pains in my testes over a decade now before I married. I have consulted doctors while they blamed it for wearing tight things. And I have for months now stopped wearing even pants, but to no avail. The pains is still there and I have been unable to reproduce. I was recently diagnosed that I’m having a lower sperm count. Less than seven million. Please doctor what can do. Help please.

    Dr. Miller: Sorry about your situation. I would need to see you in consultation to be able to help you. Please email me to schedule an appointment.

  • Rudy

    Like to know more about this. Thanks. Dr. Miller: Just email me!

  • Gard

    May I ask you how fast is Clomid in alleviating the symptoms of hypogonadism? I am a 30-year old male. For the last 12 years I have been struggling every day with insomnia, heart palpitations, muscle tensions, anxiety and exhaustion. Even though it has been very difficult to function with these symptoms, I have never had low mood and my libido has always been high. Since no somatic problem was found, I was put on many different anti-depressive and anxiolytic drugs, with no results. One year ago I tested for the first time testosterone. My T results from the last months are around 300-350 ng/dl, free T between 38-48 pmol/l, LH 4.1, 1.8, now 1.4 U/l. Additionally recently an osteopenia / starting osteoporosis has been found. No one knows whether my symptoms are related to T or not. I have been on Clomid for the last 3 weeks (25mg every other day). I still haven`t tested my blood, but I can see no improvement, my heart palpitation are even stronger than before. I do not ask for medical advice, I wanted simply to know how fast Clomid is and whether 3 weeks are enough to see improvements. It could also mean that the symptoms are not related to T. Dr. Miller: It can take several weeks to feel the effect of clomiphene, and higher dosing may be necessary in the beginning. Repeat levels need to be checked. HCG is an alternative if clomiphene is not effective. Try to find a doctor who can help you determine the cause of secondary hypogonadism. Osteoporosis and all your symptoms are consistent with low T syndrome, but there may also be additional problem.

  • Rochelle

    Me and my partner have been trying over 3 years now, I have children from a previous relationship, I have had checks and I am fine and very fertile no problems. My partner on the other hand has no previous children, I’m pretty sure he has a low sperm count, doctors won’t help us because I have children from a previous relationship. Please help us, I would be forever grateful. We are willing to try anything.

    Thank you. Dr. Miller: Sorry about your situation, Rochelle. I would be happy to help. Please email me through my website for more information about how to get started.

  • Amber

    My boyfriend had very low testosterone for someone his age, 25, so his dr put him on androgel once his levels came up they put him on clomid for several months. Now he is no longer taking clomid his body hurts and he says his male parts hurt all the time now as well. He says he feels the way he did when they first realized his testosterone was low. My question is can a man take clomid for long term use? Dr. Miller: Yes, see studies on this website.

  • Jim Mass

    My brother’s T levels dropped to the level where his weight increased to 260, pain and weakness made it nearly impossible to get out of bed. His doctor put him on Clomid and in 6 months weight dropped to about 180 and he looks like a weight lifter again and feels great at age 54.

    This prompted me to test T and low and behold, two years ago i was at 180. I went on Androgel for a year and switched to bi-weekly T injections. T dropped to 165. At brother’s recommendation, I forced my doctor to put me on Chlomid. I have not had bloodwork yet, but have lost 6 pounds and trimmed just a bit. I plan to give this 6 months and draw blood again for an update. Am I on a right course and do I need a new endocrynologist?

    Also….I have been on Levothyroxin .137 mcg for 11 years bringing thyroid numbers to normal; Simvastatin 20mg for cholesterol; Lisinpril 10mg for BP… it possible that with T levels normalized and if my present 194# at age 56 drops to an optimal 170# that my body will no longer need these meds?

  • Doug

    My doctor prescribed me 50mg of Clomid for 30 days and then will check levels. Have not started the dose yet. My question is, is anxiety a side effect. I am not overweight. Thanks

  • Panshu

    My fertility siscpaliet has suggested we try injectable fertility drugs and IUI ?The drug is called Follistim and then a HCG shot to trigger ovulation to happen. Also I am taking Metformin for PCOS. Anybody have similar situation or just some success stories? I could use a boost. We’ve had one IUI with Femara and it was unsuccessful. *Also my husband is the main cause of our problems. He is low in everything count, motility, morphology. Also alot of his sperm have DNA breakage which can cause them not to be able to fertilize or can cause miscarriage.

  • Tom

    My free T was outside normal range and total T around 350. GP said “a little low”. I know better. I responded well 10 years ago w/ 25 mg 3x/week under care of a world-class endo in this therapy. Phychotherapy helping now with PTSD from difficult childhood. Just wondering of you could give a ballpark estimate of the % of men around 50yo with secondary that have successfully “kick-started” T to normal after 3-4 months on Clomid.

  • ann

    My friend is 45 yrs old. Has high blood pressure, high cholesterol, sleep apnea, overweight 270 lbs, low T levels. Is taking statins. He tried the shot for low T and also the gel. Nothing worked. At this point he still maintains an erection but nothing like it was 5 yrs ago. Can clomid help him?

  • Sue

    My husband has been on clomid for 2 months. He recently had his levels rechecked. His testosterone increased from 200 to 706, & his estradiol increased from 20s to now 75. Has the Clomid caused this much of an elevation in estradiol? Thanks! Dr. Miller: Yes. If a person has extra body fat and doesn’t lose weight, then any way you increase testosterone it will convert to estradiol.

  • Maren

    My husband has high levels of estrogen and low testosterone. He has one testicle (one was undescended as a baby and they were unsuccessful in saving it) and about 2 years ago had a spermatocele in the remaining testicle that eventually resolved itself. We have been trying for about 15 months to get pregnant unsuccessfully. My husband’s internist put him on spironolactone for about 3 months last year, which now that I read about it, lowers testosterone instead of increasing it as he told us?!? I’d like to get my husband in to an endocrinologist who will not prescribe something that will decrease our fertility. My husband is also very overweight, and has put on about 50 pounds in the past year while we’ve been dealing with the low testosterone – he has no energy and low libido. Do you know of an endocrinologist in Utah that you think could be helpful? After reading this, I’m thinking clomid with an aromatase inhibitor would help. Just don’t want to waste time and money trying to find someone who only will do androgel or something like that. Dr. Miller: Your husband’s sperm needs to be evaluated. He may need a fertility clinic to help with sperm retrieval. Or HCG/clomiphene may help, depends on results of his evaluation. Good luck!

  • maggie m.

    My husband has recently diagnosed with. Oat syndrome and underwent a procedure to tie up a vein that was expanding and. Heating up his sperm, also a biopsy. Was taken from his testis, he is about to go On the T injection, and I’m soooooo glad I’ve found this site, clomid seems to be a better option and I think his doc did mention something about it, my question is will clomid help with oats syndrome?? Dr. Miller: It’s possible. Good luck!

  • Chey

    My husband is 23. Healthy. We went to a urologist, and his count was at 6 mil. He has been using testim gel every Monday Wednesday and Friday, and just this week has started taking clomid 50 MG, how soon do you think it will take to achieve pregnancy? Could this combination be bad? Or make pregnancy easier? Thanks! Dr. Miller: It can take a few months. Good luck!

  • Mrs. D

    My husband is 57 yrs old completed 44 radiation treatments for aggressive prostate cancer exactly one year ago, no surgery. It has also been one year since his last injection of zoladex. His PSA is .01 and his testosterone level is still less than 20, but he says he can’t live like this. Most days he cannot get out of bed. He can’t lift a 20 lb bag of dog food or open a jar. Would Clomid give him any relief? It’s about quality of life now. Dr. Miller: Clomiphene may help, or testosterone of course. Read Dr. Abraham Morgentaler’s work.

  • Amanda

    My husband is a 45 yo colon cancer survivor who now suffers from ED and low T after partial colectomy, chemo and pelvic radiation. He has tried gel and patches, which both worked the first month to bump him up over 400 and then stopped working and dropped him back down to 200’s. Shots worked great, but gave him significant polycythemia which sent his oncologist into orbit. He has off all testosterone and now been on clomid 50mg with an aromatase inhibitor for 2 months and his T level is only 203. His ED has improved in correlation with the times his testosterone has been elevated, so that seems to confirm that while there may be nerve damage he does improve when his testosterone is in range. What general circumstances causes Clomid to not work to increase T levels?

  • Anon

    My husband just started a course of clomid after we found out the testosterone he was on for over 2 years made his sperm count lower to zero. His urologist put him on clomid in the hopes that it would raise his LH and FSH enough so that he will start producing again. Is there a study that shows this is actually possible? I wish we had known about all this before his endocrinologist put him on the testosterone in the first place. I am just questioning whether or not clomid works once a course of testosterone treatment has already been administered. What are the statistics that once men have been on testosterone and their count lowers to zero, that anything can be done to reverse this? He is still young, mid 20s, and he had a tumor on his pituitary removed 3 years ago that dropped all his hormones and they stopped producing naturally. He is also on prednisone, although his is on a course right now and is tapering off slowly, desmopressin, and synthroid.

    Dr. Miller: I’m sorry you guys are having to go through all that at such a young age. There are studies showing clomiphene citrate restarts hypothalamic-pituitary-testicular axis and restarts sperm production. Whether or not it will work on him just depends on what caused his hypogonadism (low T) in the first place, and whether that has been treated. See my article about it in the blog section.

  • Sue

    My husband was diagnosed a month ago with non obstructive azospermia. He was put on clomid and arimidex to treat this and low testosterone. He had another semen analasys (1) month on meds and it is still a zero sperm count. His ultrasound showed a small varicose vein but the Dr said it shouldn’t cause the problem. Any suggestions? How long do sperm take to regenerate? Dr. Miller: Fertility is not my specialty, but I believe the life cycle of a sperm is about 70 days. Good luck.

  • Laurie

    My husband who is 45 has had a red face for several months ago. Had low T and put on clomid. T levels increased but now face is extremely red. Does clomid cause facial redness? Dr. Miller: High testosterone levels can definitely increase red blood cells, thicken the blood, and increase circulation which could cause face to redden. The doctor who is prescribing your husband the Clomid should really be following his CBC, testosterone, other hormone levels, and symptoms. It is concerning to me that you needed to contact me to answer this simple question, so please make sure you are seeing the right doctor.

  • Becky H.

    My husband, age 56, has secondary hypogonadism (primary pseudohypoparathyroidism) and has low T (210 range) and has developed intolerance to Androgel (erythrocytosis) even at one pump every other day. We have tried D-Aspartic acid with approval of his endo and it gives about the same results T-215 range as the every other day Androgel without the stimulation of hematocrit. My hubby has several underlying conditions, but functions very well and feels well on D-Aspartic. It sounds like he may be a candidate for Clomid. What would be the risk factors for trying this off-label?

  • sss

    my serum testosterone level is 349 and am experiencing ed. my doctors says testosterone level is within range and is normal. I am 36yrs old. Can clomiphene citrate help. can you advise me of any doctor in India in Mumbai who prescribes clomid.

  • PAK

    My sperm analysis test was normal sperm count 120 million fast progressive 45% slow progressive 25% non progressive 20% motile 10% morphology 90% normal round cell (puss+germ) 6-8hpf epithelial cell occassional RCB 1-2 hpf my doctor has prescribed clomifene citrate could some one help as to what role it will play in my case we are trying for baby for 2 year not concieved yet

  • Raj

    My sperm count is 15 ml/ mil and motility 10% rapid …doctor prescribed me to take chlomidfor 20 days to boost sperm count…any side effects…

  • swap

    my sperm count was 16 mil/ml and motility was 15%, started clomiphene, one month letter sperm count became 20 mil/ml and motility became 35%, how long it will take to normal sperm count

  • Jared

    My test levels are in range yet i always feel sad,depressed,lazy and testes have really shrunk to small size. My urologist has put me on 200mg of test shots every two weeks, but Ive read online that test shots actually cause them to shrink more. Should I talk to my Dr about clomid? Dr. Miller: Yes!

  • Mark

    My tested level of T was 175. I have been placed on Clomid 25mg per day. What can I expect my levels to top out at and how long till this happens?

  • Chuck L

    My Testosterone levels declined the same year that I started taking statins. This could be a coincidence but wanted to know if there is any evidence of statins causing a decrease in testosterone.

  • Happy Again

    My testosterone levels were dipping down as low as 85. I tried the creams and gels, (Androgel and Axiron) and nothing was raising my t levels until I starting taking 1/2 of a clomid citrate daily. I knew in the first 2 weeks it was working and my first blood test, my testosterone level was 586!!! Everything was better including the ED. My chlorestorol levels even dropped from 250 to 207!!! I’m telling you, this is a magic pill. I feel like I’m 25 again (I’m 46) and I’m so happy. So is my wife!!!

  • John

    My TT levels are 265 ng/dl and I am 34 y.o. male. I was previously put on TRT by another doctor. My family doctor is anti TRT. I had very severe sleep apnea for many years(diagnosed while on TRT). My family doc convinced me to come off TRT and let my body make its own T. What a mistake. During this entire off time from TRT which was 16 months my TT never got over 288 ng/dl. I was on low dose Arimidex as well during this time off. 0.25 mg E3D. My family doc will not prescribe clomid due to it being “off label”. I gained 30 pounds of viseral fat being off TRT for the 16 months. My family doc told me my testosterone levels are fine and I need wellbutrin or an SSRI because there is mo proof my T is low cause technically I am 1 nmol/l above the low end. I have discontinued seeing this this family doctor. He told me to come off hormone replacement then my levels are low and he says my Testosterone is fine?

    My LH is 4 IU/L and FSH is 2 IU/L will clomid work for me given my past snd being on TRT for 2.5 years straight.

    I’m currently on HCG and my TT is 500 ng/dl. My dose for HCG is 500 I.u. 3 times a week with 0.25 mg Arimidex E3D.

    I am looking to see if clomid 50 mg EOD is a suitable dose for me and if it would be enough to help me.

    Thank you for your time Dr. Miller

  • koolx

    my uro prescribed me clomid. for my low T count. i’m hesitant to try it because i’ve read many complaints in online forums from men who said it caused low libido. what are your thoughts on this? should i try it? Dr. Miller: I haven’t heard complaints of low libido.

  • R

    My urologist must have been ahead of the curve on this. I went to him in July 2005 after i found out i had a low sperm count (20,000). He tested my testosterone levels and they were low as well. HE started me on clomid and after 3 years my wife and i had a son. We went back 2 years later and I started up on the clomid again and 7 months later my wife was pregnant with our daughter. I took it daily. I do not want any more children but i want to go back on because i believe this is the safest way to increase my T levels. I’m just curious about side effects after going off. I have noticed a lack of sex drive since going off…Dr. Miller: If cause of secondary hypogonadism is not discovered and/or reversed, then coming off of clomiphene will cause cause low T symptoms and low sperm count to recur.

  • kyle

    No gels. Injections work to raise t levels. After y6 months of treatment my levels are 267 were as low as 70’s. Can Methadone cause low T? Orsstreet feuds that ate snorted? Did some years ago. I’m 42 n have had problems for over 13 yrs now. Will Clomid help me?

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  • Mike

    On average, if I come to you and your tests show I have hyopogonadism and am prescribed Clomid, am I taking this pill for life because once I stop my testosterone plummets again or is it something I can take for a few months/year and my Testosterone levels will stay fairly high? Thanks!

  • Jeff

    P.S. Before Clomid my T was at 342 ng/dL and my free T was at 8.5. I took Clomid on my own since my Dr. was unaware of this off-label use of Clomid. Presently my PSA level is 1.2 and four previous tests were quite varied from 272 to 496 ng/dL and now it is 1100 with no discernable affect. Thank you.

  • brian c.

    prescribing clomid or other steroids is nothing more than treating the symptoms and not the cause. low test. and high blood fats are commonly caused from low thyroid. depression and anxiety are many times caused by a low fat diet, your brain is almost all fat so take cod liver oil twice a day and keep it cold. fix your thyroid and your test. level will double and your blood fats will drop like a rock, not to mention your hdl will go up. treat the cause not the symptoms!! Dr. Miller: Thank you for your comment. It’s true, increasing fat in diet and treating low thyroid can help increase testosterone. Clomiphene citrate should only be prescribed after comprehensive evaluation and treatment of reversible causes.

  • Chris P.

    Radical prostatectomy done, now on Lupron. Doc said testosterone replacement would bring cancer back (PSA near zero for 2 years). Would I be a Clomid candidate? Dr. Miller: Chris, testosterone replacement is not absolutely contraindicated after prostate cancer. Whether or not clomiphene would work largely depends on blood work results.

  • J

    Say one has shut down their natural HPTA axis with testosterone enanthate….and after not touching it for a long time their natural test is low. My urologist said my gonads were a good size and he said more than likely secondary. I asked about clomid and he wasn’t sure and said he would do research…haven’t heard back in 4 weeks and decided to start…100mg clomid 7 days then down to 50mg…strength in the gym is up but lack of energy and sex drive still…would tamoxifen (nolvadex) be unsafe to add? In order to help LH and reduce estrogen? Dr. Michael Scally had recommended on his website…but nice to get other doctors opinions. Dr. Miller: I’m sorry but I cannot give personal medical advice here. You need to have blood testing and consultation, otherwise you are just guessing. In general, I only recommed aromatase inhibitors for short period until weight loss is achieved.

  • skilly

    Second, should TRT be discontinued if clomid is used to increase T levels? Dr. Miller: Generally, if it works, then yes.

  • mike B.

    Shat about men who have had vasectomies? Will Clomid help them also? Dr. Miller: Vasectomies are not a contraindication to trying clomiphene for secondary hypogonadism in men. Yes, it should still work.

  • Ritesh / Male / 32

    Should I start taking clomid for raising testosterone without getting testosterone test? I am experiencing week erection low libido and loss of strenght while workout.

  • Aaron

    Should women taking clomid also combine it with AI or weight loss? Dr. Miller: I am not an expert in the use of clomiphene in women, however I do know that prescribing an aromatase inhibitor to women can cause serious harm.

  • Mark Unomuzo

    Sincerely speaking I have been really educated by this medium. However Can a man having slightly high prolactin,low sperm count continue with clomid after taking it for about 4 weeks?

  • alwerfaly

    Some kidney transplant patients have a problem with erectile dysfunction and poor sperm movement, what about the usefulness of Clomid for them and What about interactions the Clomid with kidney transplant drugs

  • MIKE

    SOME time ago I was on a steroid cycle – testosterone 400 and deca durabolin 300 every week. Now I started taking clomid to bring back my natural testosterone production- my question is: how much should I take it and what doses. Thank You a lot in advance. BTW I`m 33 now. Dr. Miller: Sorry I can’t give personal medical advice here.

  • John Galloway

    Thank you for posting this wonderful article and answering so many questions. I just began taking clomiphene (25mg/qd) primarily to counteract testicular shrinkage from TRT (100mg injectable/week). Is it ill-advised or safe to be on TRT while taking clomiphene? I realize it may depend on one’s T levels (my last test 688 ng/dl serum, 17.2 pg/mL) and that you can’t recommend any specific change in therapy. Mainly wondering if it’s harmful to be taking both regimens. Thank you!!

  • Foo

    Thank you for this article. My T gradually reduced from 3.99ng/ml in 2011 to 3.29 in 2012 and 2.93 in 2013. My LH is also in the low end while prolactin and FSH are normal. MRI in pituitary and ultrasound on testicles turned out normal. Did a SFA and I have 50 mil sperms per ML with 20% sluggish and 10% dead which is also good. I went to 3 specialists and they keep sugarcoating the issue as my T levels still fall under the normal range. I can get Clomefene Citrate without prescription in my country. Could you please tell me whether it will affect my fertility in a negative way? Dr. Miller: Clomiphene improves sperm count.

  • David

    Thank you for your excellent article and for taking the time to answer these comments.

    Do you prescribe any aromatase inhibitors to your patients to help manage risks associated with hypercoagulation from Clomid? I wonder if asprin would help reduce these risks as well. Dr Jeffry Dach has an interesting article that mentions this.

  • liberty

    Thanks Dr. Miller for making this known. I had a T level of 70. Clomid (50mg 2x daily) has moved me back to 450+, with free T at 16. I found a good urologist after my GP prescribed Androgel, which did nothing in 3 months. He put me on Clomid, and it worked.

  • Jason

    Thanks for the article. I’m a 37 year old male with low T. I’ve been doing injections for just over a year now. I’ve recently been diagnosed with polycythemia, and am now doing phlebotomy to address it. My Hemotologist is currently testing me to see if it’s being caused by something else but there’s no doubt in my mind that the injections are causing it. I would really like to try clomid. I’m done with injections.

  • Steve

    Thanks for the explaination in detail how clomid can help with low test levels. Low testosterone can also be treated by having natural foods like celery for testosterone which i just went through based on solid sciantific studies.

  • S.

    Thanks you for sharing your insight on this incredible blog. very useful information. I have been diagnosed with secondary hypognadism and my Dr. has put me on 50mg Clomid every-day for 3 months. I started taking the medication only 10 days ago and have started feeling a little better in terms of mood, energy etc. however My sexual function has had a severe impact. I am no longer able to achieve or maintain erections. this is happening only after starting clomid. prior to that I did have low libido and very mild ED. Are these side effected of clomid? Dr. Miller: Thank you for your kind words. If testosterone converts to estrogen then that could cause low libido. I hope this helps. Please talk with your doctor.

  • T

    Thanks you for the very helpful blog. I’m 24 yr old and I’m suffering DE problem. My result test show me that I have low LH and FSH and my doctor recommended me using Clomid, so should I use Clomid to solve my problem? I still don’t have wife or any plan to have children yet. Dr. Miller: If Testosterone is low, then you need to make decision with your doctor.

  • Anghelo

    the clomid sttumlaies maturity of the folicles in my last ultrasound the doctor said i had one egg ready to be released from my left overy but that i have several VERY small ones in my right overy prepairing for next month. he asked if i wanted to skip this cycle (going through artificial insemination) and wait for the right overy’s egg supply next month. i am going in tomorrow to see if it is time to use the injectable drug PREGNYL 10,000 units in one dose. the pregnyl is a hormone that sttumlaies my overy forcing it to drop eggs. the doctor tells me there is ONLY one egg that is mature enough to possibly be fertilized so, i don’t THINK it’s the HCG drug that causes maultiples HCG prepares the body for pregnancy and actually tricks the body into thinking it is. i was told that when i get pregnant i will need to continue with hormone shots until i am at 12 weeks to HELP me from miscarriage (although i’ve never had a miscarriage before). the HCG does cause eggs to spill out, but the doctor knows by ultrasound how many are actually viable

  • Jeff

    The first time I took Clomid I felt the positive effects within days. Since then I’ve never been able to duplicate the success with Clomid. Is HCG a viable alternative for people who don’t respond to Clomid? Dr. Miller: Yes.

  • Dan in Denver

    This website has changed my life. Early last year when I was just turning 48, for the first time in my life I started to have ED issues. I mentioned it to my family doc and after my T came back at 249, he started me on testosterone shots. But instead of weekly or even every two weeks, he wanted me to have shots on three week intervals. Geez what a rollercoaster ride that was. After I learned more about T injections, I should have been on weekly shots due to short half-life of testosterone cypionate. I explained this to him and then he suggested to try Aveed. Its supposed to be an injection only 4x year so it sounded good. But the first 3 weeks my pecker completely shut down. And I mean zero movement (and my wife is hot). My T came back over 2000! Then I came across this website and asked him for Chlomid. He said he wasn’t familiar with it and would not prescribe it (just like Dr Miller said). I found another doc who was reluctant but gave in and said he would try it only for six months. Now my T is in the 600’s, my pecker is performing when called upon and I’m doing great in the gym. But I’m REALLY worried because now that feeling back to normal, he said that 6 months is it for the Chlomid, then we wants to put me on the T pellets. So I will have to go in search of another Chlomid friendly doc. Wish me luck because I’m thinking I will soon be on another T roller coaster only because I cant find anyone out here in Denver like Dr Miller.

  • Tom

    Two questions Dr Miller. can clomid reduce testosterone in the right circumstances. And does raising testosterone levels with clomid increase the risk for heart disease and prostate cancers the way we are taught that testosterone replacement can.

    Dr Miller, I am a primary care provider. I often field concerns from overweight men in their 40s with high stress jobs, poor diets, no exercise, who raise testosterone concerns as a reason for their fatigue, low libido, and weight problems. Imagine my skepticism. I recently ran into a, fit, active 27 year old gentleman new to my practice, who was placed on clomid for several months by another provider, primarily for the symptom of impotence. Ts in the 300s, and no evidence for secondary reason for ‘low’ T. After the clomid ,his testosterone level dropped (to lower 300s) although I suspect this was just a variance in the lab timing or using different lab facilities, but it prompted this alternate provider to start a rather large dose of topical testosterone. Any thoughts on clomid reducing T levels?

    I shy away from using testosterone replacement in most of these men for the reason that they are looking for an alternative to a healthy lifestyle to fix their problems, and I worry primarily about the cardiovascular risk increase. Do you think these worries are unfounded and given that clomid promotes the bodies own testosterone to increase, should clomid be safer?

    Thanks for your time.

  • Jay C

    Went to my primary care physician after feeling cruddy for a while. For about a year she had me on Cypionate every two weeks at about 250mg. T was still very low so went to urologist. Realized I needed to stop taking it because my wife wants more children. I am 31 years old and Urologist says Clomid and hcG are not warranted at this time even though my blood work showed all levels in the bottom of the range. FSH Gonadotropin 3.4 Total test 309 Albumin 4.3g/dl Prolactin 7.2 ng/ml Why does my urologist not want me to take Clomid or hcG in Illinois? I think it would be very beneficial.

  • Jennis

    What a joy to find someone else who tihnks this way.

  • Dr PJS

    What are some of the typical aromatase inhibitors used to keep estrogen levels from becoming too high when taking Clomid? I realize that on your site you advise losing weight to help with estrogen levels but I wonder if Clomid + an AI might help with the weight loss. Dr. Miller: Yes, aromatase inhibitors may be used until weight loss is achieved but I haven’t seen them help with weight loss. Anastrozole is a type of aromatase inhibitor.

  • Stef

    What are the side effects of clomid? Dr. Miller: Main side-effect is possible visual changes, but that is rare.

  • Derrick

    What are your thoughts on using both hcg and clomid together to combat hypogonadism? Any informative articles on this?

  • Jake C

    What do you think about pairing clomid 50mg a day and 3mg a day daa to raise test test levels? I’m too young and don’t want TRT as I’m 22

  • AW

    What do you think of D Aspartic Acid? This study showed a one third increase in testosterone.; Since it’s a naturally occurring amino acid, do you think it might be safer than Clomid?

    Dr. Miller: thank you and yes

  • Edgar L.

    What is a normal range of testosterone for a 30 year old male?, i had my right testicle removed due to cancer when i was 25, i’ve never had my T. Level tested before surgery, so I cannot tell which was my level before with two testicles. but i can tell I felt differently after, i gained a little weight even tough i had an active life gym 3-4 times a week and have a decent diet,

    I noticed that my erections are a little more difficult to achieve, not impossible but i do feel i require more stimulation than before. and I do feel sometimes I am not as hard as I used to be, I also feel that I depress easily, before the surgery I was a very optimistic and positive person. My normal T. Level tests have come from 250-320 without any treatment. Some doctors had told me that this level might be OK and normal for my body and stopped pursuing a Testosterone solution, however i decided to investigate more because I read a normal range to my age would be over 600 T level. I went to an endocrinologist and he ordered some more tests, My LH came in range at 5.19 mUI/mL and my FSH is higher than range 12.78 mUI/mL. I would like to suggest a combinated treatment to my endo. Could I combine testosterone gel and clomiphene? I would like to prevent my left testicle from producing the few testosterone that it produces now and avoid low sperm count. In the past one of the doctors recommended just clomiphene, it rose my T. up to 415 only, i’m not sure if i took it long enough to give up on it, after that I tried just gel one dose a day recommended by my urologist, but it rose me over the range after three months and my urologist blamed me of abusing it, he said I should stop taking any treatment and I did. before this I also tried alternating one day of gel and one day of 50mg clomiphene and I went up to 538 after a month, and then I checked it again after 2 months and was up to 800, which according to my urologist it was high as well so I stopped treatment, but I would like to restart it and now with a different doctor. Let me know any comment. Thanks. Dr. Miller: Sorry about your cancer, that must have been rough. Yes, you want to be on higher side of testosterone range, 800 is not too high. 300s is definitely too low. Different clomiphene dosing may help, or HCG, or likely testosterone with clomiphene may be necessary in cases like yours where there is some primary hypogonadism. You need to find another doctor who is comfortable with higher testosterone levels.

  • Brian

    what is the best time of day to take clomiphene?

    • I generally recommend a time of day when it can be taken consistently, whether morning or night.

  • G

    When is the best time of day to sample blood for Testosterone levels? Dr. Miller: If you want to check peak level, then 8am.

  • Jeff

    Whenever I take even a very low dose of clomid (12.5mg) I feel very anxious and have headaches for a few days later. I feel that the clomid is making a difference even after the first dose but I can’t seem to stay with it because of anxiety. Is that normal and if you stay with the low dose eod does anxiety and headaches usually go away.

  • Chria

    Will the use of clomiphene after raising testosterone make my erections come back, if the cause of the ED was due to low T.

  • Shields

    Would like to know if Clomiphene would help my E/D from prostate cancer radiation therapy two yrs ago- still have low libido and Cialis/Viagra not much help.

  • FM61

    Would low T itself cause azoospermia even though LH & FSH levels were in normal ranges? Would clomid be beneficial to a person in this situation?

  • Joshua

    Would there be a concern of to much estrogen build up if taking clomid? I understand that it blocks the estrogen from telling the hypothalamus and pituitary that there’s enough, my concern is that it continues to build up and create estrogen symptoms. If this is not the case is there any way to explain why there isn’t such a build up?

  • BART

    Wow. I can’t believe how many questions your have loyally answered. I had taken steroids for many years; however ,I would always finish my cycle with hcg, nolvadex, clomid and proviron I worked out in three years. I gained a lot of we ight since (220 kg.) If my obesity is causing low t levels would it be ok to take clomid and an antiaromatizor until my weight is normal and then stop the neds. Obviously I would exercise. Being fat with low t levels makes losing weight very hard; viscous circle. Or should i wait to lose weight and then check levels.My reading was 5.5 nmol/lm thanks

  • Paul

    Yes I took propecia and had a quit 3 months ago.. I went to see a urologist about a month ago.. My total test scores were 383 and lh was 2.5 and fsh was 2.5.. Uro put me on test cream for 6 weeks I have noticed small improvements.. I go back in 2 weeks and he mentioned he might put me on Clomid.. I experienced ed while on the drug… Do u think the Clomid will help me??? I have been off propecia for 3 months.. I get really good responses from ed meds like Viagra and Cialis at the moment.. Uro mentioned Clomid in our last visit?? Dr. Miller: Yes, clomiphene may help.

  • HR

    Your article is good.i have count of 35% active .How clomid does work for improvement?How long course of clomid i should take??

  • Peter Ross

    Thank you for this excellent review of Clomid. I am 62 and was prescribed testosterone [ both creams and IM injections] because of low free T. While both my free and total T increased, so did my estradiol and red blood cell count. The increased estradiol was unmanageable and basically negated any of the effects of T treatment. And worse, when I discontinued the T therapy, I developed ED; something that I never had before. My current free T is 3.0 [out of range low] and total is 520. Wondering why the MD never considered Clomid? Seems like you would recommend it for someone like me, but I do not want to experience any of the horrible rebound I had when stopping T treatment. Thanks, Pete

    • Any testosterone therapy, whether actual testosterone or CC, can increase estrogen levels due to testosterone conversion to estradiol. Blood levels need to be carefully monitored. Yes, most doctors are not aware about the CC option for secondary hypogonadism.

  • Jerome Desilets

    I am really interested in treatment options and new advances for hypogonadism, I am especially interested in the use of clomid or clomiphene citrate for curing, or treating the cause and root of hypogonadism, have been dealing with hypogonadism and I am having no luck in finding a doctor that will prescribe clomid, I did have a doctor that prescribed hcg, but my medical coverage blue cross cut me off after 3 years and my doctor moved away and I am left with a poor excuse for a doctor, who gave me a hard time about dealing with my hypogonadism even telling me that just because a dogs nuts get cut off doesn’t mean it is going to die, how would like to have a doctor like that, I’m in Powell River BC Canada, isolated community and we don’t get any real choice in who are doctor is?! Any recommendations appreciated.

    • It’s very sad when a physician downplays and/or mocks a patient’s complaints. I hear about it every day. I would look for a doctor at a fertility clinic, as they as more knowledgeable and experienced in using CC.

  • Doug

    Great article! Is Clomid easy to come off of? Will test levels plummet?


    • It depends on the cause of one’s secondary hypogonadism and whether that has been treated. In comparison though to coming off of actual testosterone, the drop in testosterone occurs much more slowly.

  • Tom

    Based on your information, I filled the prescription. After reading the list of possible side effects provided by CVS, I will not be taking CC! Apparently some vision problems are not reversible. Serious abdominal issues, cardiac events, breathing issues, cognition issues are just a few listed side effects. Far too many drugs with serious and lasting side effects are being used for non-life saving events. It’s time for patience and doctors to be responsible about prescription drug abuse!

    • The information on this website is not personal medical advice. Treatment with CC or any drug, should be based on a physician’s recommendation, in addition to weighing the benefits of treatment vs. the risks of side-effects.

  • john r

    I find it odd that someone would balk at the list of *possible* side-effects, when men with a low-T condition have a 33% higher mortality rate!!!!!! I’d rather take my chances with CC, which I have. My T total was 223 and after 4 weeks of CC it is now 520, so very much improving. I think I feel a little better, and certainly have noticed positive physical changes with the reproductive parts. We’re going to continue treatment and re-assess in 6 months. I’m also combining CC with Anastrazole which is an estrogen blocker I believe.

    I’m 49. Have had the low-T diagnosis for 4 years before I started this treatment. My main problems were a highly noticeable loss of cognitive function (focus and memory) as well as complete loss of labido…. could not continue dealing with these problems any more. I just wish that my Cigna insurance would cover the costs of the medicine… they say this is not “preventative” so they won’t cover.

    • Thank you for your comment! I see such responses all the time, and they warm my heart. Good thing clomiphene citrate is relatively inexpensive. It’s worth it to check around, as sometimes places like Costco have great pricing on generic prescription medications.

    • Joel Reinert

      John you are on the right track. HAVE BEEN ON BOTH FOR 3 YRS AND FEEL GREAT. Not to step on anyone here, you need to watch your estrogen levels. High levels in men are tragic with time. The life extension foundation has guidelines for estrogen in men.

  • JCard

    I found your article, and agree with it. I am a 41 yr old male and I am currently on it. The difference for me is night and day and I am on a weak dose. 25MG every other day. I used it once before for 6 months with no problems.

    My concern is that since it is off lable my docotor won’t keep me on it for long. Is this something that can be cylced if the effects don’t last?

    • Yes, clomiphene citrate can be cycled for the treatment of secondary hypogonadism, based on one’s individual response to it.

  • Kelly Fraser

    My son is now 18 years old and he finished chemotherapy for leukemia in Sept of 2014. He has a low testosterone level. Initially we gave him one shot of testosterone each month for 3 months and that ended up starting his puberty process like we were hoping (the help cancelled it and it never started on its own). However now….2 1/2 years later…..his levels are low again. Our Dr. put him on CC at a dose of 25mg a day for 6 months. Is it likely that this will have major side effects for him due to his age? If so…what might they be? Mood swings, breast enlargement, a voice going higher again…etc? Also do you think this will be a long term thing for him or done in the six months? Thanks for your help. Kelly (concerned Mom)

    • Sorry so late to reply and sorry to hear about your son. That must have been a difficult time for all in the family. Side-effects can happen with any medication but with close supervision a doctor would prevent them from lasting for too long. You have to compare the risk of side-effects and to the benefits.

  • Ugly Bear

    I am 46 years old. I am pretty healthy and in great shape yet I started having ED problems also other issues like lack of energy, forgetfulness etc. My urologist prescribed me Clomiphene Citrate 25 mg daily. My T level went from 422 to 803 in two months. This is great but I still feel the same way. I don’t feel any different than I did when it was in 400s. My doctor said most guys don’t feel any different. I don’t get it, what’s the point using it then. Is it normal not to feel more energized and better erection?

    • You should definitely be feeling better. Your estrogen may be too high or you may have another hormone deficiency or other problem that is causing your symptoms. A comprehensive evaluation is needed.

  • Michelle Ray

    My BF (53 and otherwise healthy) had his prostate removed 2 yrs ago and now has zero sex drive, and bladder inflammation. He is tired ALL THE TIME! The oncologist insists Test. therapy is not safe for him to take. He wont budge. This is a top Beverly Hills md. He is cancer free for 2 years. Is this an option? Thanks for any help!

    • Has his testosterone level been checked? Other hormones checked? Try a urologist who is comfortable with prescribing hormones in patients with a history of prostate cancer. Check out the book, Testosterone for Life, by Morgantaler. Depending on the exact circumstances, I may also be able to help as well.

  • Marc Gonzalez

    I’m 27y/o I’ve been on trt for almost a year I was improving very well I got off all my phsychatric meds but recently been having all those symptoms associated with low t come back and my t levels went down bact to where I first started that is 197dl total t and hasn’t improved for 16 weeks now and my free testosterone seems to be at a normal rate slowly improving. I’m on 200mg injections every 2 weeks and now my doctor is putting me on 25mg clomid every other day. My question is that are there any bad side affects I should worry about and will it help improve my over all well being my sleep hasn’t been well with night terrors and sleep paralysis and anxiety comes and goes like a rollercoaster no depression yet but I fear for it to come back since it was so bad I tried to commit suicide so I don’t ever want to feel that low in life ever again. My libido is okay I guess but I have noticed my testicles slightly shrunk but I didn’t have big testicles to begin with I also had little manly features like body or facial hair and now slowly starting to get that too more so facial hair not chest so will this new med make me a hairy guy and will I get back my sense of well being like I felt with my first 4 months of trt. I feel like I hit a plateau on my treatment I just don’t want to go back to the way I felt when I was going through depression, low libido, anxiety, night terrors, and mood swings so feed back would be greatly appreciated cause I’m a little confused on how this will help me since I seem to forget all my questions when I’m at the Dr office.