Clomiphene Citrate (CC or Clomid) – A Testosterone Therapy Alternative for Men with Low Testosterone Levels

Shira Miller, M.D.Men512 Comments

A Testosterone Therapy Alternative for Men with Low Testosterone Levels Whether you are a 30, 50, 80 or even 110 year old man, having low testosterone levels (hypogonadism) is neither fun nor healthy. The symptoms of low testosterone in men range from lack of energy, depressed mood, loss of vitality, muscle atrophy (sarcopenia), muscles aches, low libido, erectile dysfunction, and ... Read More

Abstract: Clomiphene Citrate Safe for Long-Term Management of Hypogonadism

Shira Miller, M.D.Abstracts, Men

BJU Int. 2012 Mar 28. doi: 10.1111/j.1464-410X.2012.10968.x. [Epub ahead of print] Clomiphene citrate is safe and effective for long-term management of hypogonadism. Moskovic DJ, Katz DJ, Akhavan A, Park K, Mulhall JP. Source: Sexual & Reproductive Medicine Program, Urology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Abstract Study Type – Therapy (population cohort) Level of Evidence 2a What’s known on the subject? and What does the study add? Clomiphene citrate(CC) … Read More

Abstract: Sleep Restriction Reduces Testosterone Levels in Young Healthy Men

Shira Miller, M.D.Abstracts, Men

Research Letter Effect of 1 Week of Sleep Restriction on Testosterone Levels in Young Healthy Men JAMA. 2011 Jun 1;305(21):2173-4. Rachel Leproult, PhD; Eve Van Cauter, PhD Source: Department of Medicine, University of Chicago, Chicago, Illinois, USA. To the Editor: Chronic sleep curtailment is endemic in modern societies. The majority of the daily testosterone release in men occurs during sleep. 1 Sleep fragmentation and … Read More

Common Symptoms of Low Testosterone

Shira Miller, M.D.MenLeave a Comment

What are common symptoms of low testosterone? In men, the symptoms of low testosterone range from decreased sexual thoughts, erectile dysfunction, increased body fat, muscle aches and decreased muscle mass to anxiety, depression, lack of motivation, excessive sleepiness, and fatigue (especially in the afternoon.) Many of the above complaints may be caused by other disease processes, but checking a testosterone … Read More

Abstract: Symptoms of Low Testosterone or Hypogonadism

Shira Miller, M.D.Abstracts, Men

Int J Clin Pract. 2010 May;64(6):682-96. A practical guide to male hypogonadism in the primary care setting. Dandona P, Rosenberg MT. Division of Endocrinology, Diabetes and Metabolism, State University of New York at Buffalo and Kaleida Health, Buffalo, NY, USA. Abstract There is a high prevalence of hypogonadism in the older adult male population and the proportion of older men … Read More

Abstract: Low Testosterone Is a Cardiovascular Risk Factor

Shira Miller, M.D.Abstracts, Men

Int J Impot Res. 2009 Jul-Aug;21(4):261-4. Welcoming low testosterone as a cardiovascular risk factor. Maggio M, Basaria S. Department of Internal Medicine, Division of Endocrinology & Metabolism, University of Parma, Parma, Italy. Abstract Male hypogonadism now has a new spectrum of complications. They are mainly cardiometabolic in nature.  Low serum testosterone levels are a risk factor for diabetes, metabolic syndrome, … Read More

Abstract: Low Testosterone and Mild Depression

Shira Miller, M.D.Abstracts, Men

J Clin Psychiatry. 2009 Jul;70(7):1009-16. A randomized, double-blind, placebo-controlled study of testosterone treatment in hypogonadal older men with subthreshold depression (dysthymia or minor depression).  Shores MM, Kivlahan DR, Sadak TI, Li EJ, Matsumoto AM. Geriatric Research, Education, and Clinical Center, Veterans Affairs (VA) Puget Sound Health Care System, Seattle, Wash. 98108, USA. Abstract OBJECTIVE: Hypogonadism and subthreshold depression are common … Read More

Abstract: Low Testosterone Increases Risk of Death

Shira Miller, M.D.Abstracts, Men

J Clin Endocrinol Metab. 2008 Jan;93(1):68-75. Low serum testosterone and mortality in older men. Laughlin GA, Barrett-Connor E, Bergstrom J. Department of Family and Preventive Medicine, School of Medicine, University of California, San Diego, 9500 Gilman Drive, MC 0631C, La Jolla, California 92093, USA. Abstract CONTEXT: Declining testosterone levels in elderly men are thought to underlie many of the symptoms … Read More

Abstract: Endogenous Testosterone and Mortality Due to All Causes, Cardiovascular Disease, and Cancer in Men

Shira Miller, M.D.Abstracts, Men

Circulation. 2007 Dec 4;116(23):2694-701. Epub 2007 Nov 26. Endogenous testosterone and mortality due to all causes, cardiovascular disease, and cancer in men: European prospective investigation into cancer in Norfolk (EPIC-Norfolk) Prospective Population Study. Khaw KT, Dowsett M, Folkerd E, Bingham S, Wareham N, Luben R, Welch A, Day N. Source: Clinical Gerontology Unit Box 251, Addenbrooke’s Hospital, Cambridge CB2 2QQ, UK. kk101@medschl. Abstract BACKGROUND: The relation between … Read More

Abstract: Testosterone Replacement Improves Sexual Function in Men

Shira Miller, M.D.Abstracts, Men

J Sex Med. 2007 Nov;4(6):1757-62. Subjective sexual response to testosterone replacement therapy based on initial serum levels of total testosterone. Reyes-Vallejo L, Lazarou S, Morgentaler A. Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA. Abstract INTRODUCTION: Testosterone replacement therapy (TRT) has been shown to be beneficial for men with hypogonadism. However, it is unknown how well hypogonadal … Read More